Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | SANA_TNF_SIGNALING_DN |
| Enrichment Score (ES) | -0.52354705 |
| Normalized Enrichment Score (NES) | -1.5357823 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 132 | 3.451 | 0.0543 | No |
| 2 | ANTXR1 | ANTXR1 Entrez, Source | anthrax toxin receptor 1 | 1060 | 1.913 | 0.0227 | No |
| 3 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 2109 | 1.166 | -0.0315 | No |
| 4 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 2139 | 1.152 | -0.0123 | No |
| 5 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 2505 | 0.985 | -0.0204 | No |
| 6 | HDAC2 | HDAC2 Entrez, Source | histone deacetylase 2 | 2644 | 0.931 | -0.0132 | No |
| 7 | SNRK | SNRK Entrez, Source | SNF related kinase | 3029 | 0.816 | -0.0259 | No |
| 8 | NOS3 | NOS3 Entrez, Source | nitric oxide synthase 3 (endothelial cell) | 3460 | 0.700 | -0.0440 | No |
| 9 | DNAJB4 | DNAJB4 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 4 | 3979 | 0.573 | -0.0709 | No |
| 10 | KRT18 | KRT18 Entrez, Source | keratin 18 | 4094 | 0.550 | -0.0689 | No |
| 11 | PEA15 | PEA15 Entrez, Source | phosphoprotein enriched in astrocytes 15 | 4298 | 0.505 | -0.0743 | No |
| 12 | BGN | BGN Entrez, Source | biglycan | 4603 | 0.442 | -0.0881 | No |
| 13 | ATP1B3 | ATP1B3 Entrez, Source | ATPase, Na+/K+ transporting, beta 3 polypeptide | 5309 | 0.308 | -0.1333 | No |
| 14 | PRKACB | PRKACB Entrez, Source | protein kinase, cAMP-dependent, catalytic, beta | 5634 | 0.253 | -0.1521 | No |
| 15 | CLU | CLU Entrez, Source | clusterin | 5735 | 0.236 | -0.1549 | No |
| 16 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 6230 | 0.162 | -0.1877 | No |
| 17 | PPP1R16B | PPP1R16B Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 16B | 6358 | 0.140 | -0.1943 | No |
| 18 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 6495 | 0.119 | -0.2019 | No |
| 19 | CTNNAL1 | CTNNAL1 Entrez, Source | catenin (cadherin-associated protein), alpha-like 1 | 6654 | 0.092 | -0.2116 | No |
| 20 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 6970 | 0.043 | -0.2336 | No |
| 21 | KCTD12 | KCTD12 Entrez, Source | potassium channel tetramerisation domain containing 12 | 7612 | -0.053 | -0.2789 | No |
| 22 | EPAS1 | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 7688 | -0.066 | -0.2831 | No |
| 23 | NTN4 | NTN4 Entrez, Source | netrin 4 | 7899 | -0.101 | -0.2965 | No |
| 24 | ACE | ACE Entrez, Source | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 8382 | -0.178 | -0.3280 | No |
| 25 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 8681 | -0.226 | -0.3454 | No |
| 26 | HTR1B | HTR1B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1B | 8730 | -0.234 | -0.3445 | No |
| 27 | SASH1 | SASH1 Entrez, Source | SAM and SH3 domain containing 1 | 8824 | -0.250 | -0.3466 | No |
| 28 | TXNDC5 | TXNDC5 Entrez, Source | thioredoxin domain containing 5 | 9242 | -0.318 | -0.3709 | No |
| 29 | VWF | VWF Entrez, Source | von Willebrand factor | 9658 | -0.385 | -0.3938 | No |
| 30 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 9724 | -0.395 | -0.3912 | No |
| 31 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 10443 | -0.527 | -0.4333 | No |
| 32 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 10853 | -0.609 | -0.4516 | No |
| 33 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 10934 | -0.627 | -0.4458 | No |
| 34 | ATP5A1 | ATP5A1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 12010 | -0.935 | -0.5063 | Yes |
| 35 | CAPNS1 | CAPNS1 Entrez, Source | calpain, small subunit 1 | 12061 | -0.954 | -0.4922 | Yes |
| 36 | DDR1 | DDR1 Entrez, Source | discoidin domain receptor family, member 1 | 12095 | -0.965 | -0.4767 | Yes |
| 37 | SSFA2 | SSFA2 Entrez, Source | sperm specific antigen 2 | 12101 | -0.968 | -0.4592 | Yes |
| 38 | CDK2AP1 | CDK2AP1 Entrez, Source | CDK2-associated protein 1 | 12397 | -1.088 | -0.4604 | Yes |
| 39 | TXNIP | TXNIP Entrez, Source | thioredoxin interacting protein | 12552 | -1.166 | -0.4499 | Yes |
| 40 | APLN | APLN Entrez, Source | apelin, AGTRL1 ligand | 12561 | -1.170 | -0.4288 | Yes |
| 41 | TM4SF1 | TM4SF1 Entrez, Source | transmembrane 4 L six family member 1 | 12632 | -1.201 | -0.4117 | Yes |
| 42 | PCTP | PCTP Entrez, Source | phosphatidylcholine transfer protein | 12639 | -1.205 | -0.3898 | Yes |
| 43 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 12712 | -1.239 | -0.3721 | Yes |
| 44 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 12966 | -1.393 | -0.3646 | Yes |
| 45 | GLCE | GLCE Entrez, Source | UDP-glucuronic acid epimerase | 13427 | -1.904 | -0.3626 | Yes |
| 46 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 13481 | -1.973 | -0.3299 | Yes |
| 47 | SMYD2 | SMYD2 Entrez, Source | SET and MYND domain containing 2 | 13485 | -1.980 | -0.2935 | Yes |
| 48 | CABLES1 | CABLES1 Entrez, Source | Cdk5 and Abl enzyme substrate 1 | 13508 | -2.031 | -0.2575 | Yes |
| 49 | PRKCH | PRKCH Entrez, Source | protein kinase C, eta | 13517 | -2.043 | -0.2203 | Yes |
| 50 | NT5E | NT5E Entrez, Source | 5'-nucleotidase, ecto (CD73) | 13578 | -2.183 | -0.1842 | Yes |
| 51 | MTUS1 | MTUS1 Entrez, Source | mitochondrial tumor suppressor 1 | 13647 | -2.329 | -0.1460 | Yes |
| 52 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 13687 | -2.451 | -0.1035 | Yes |
| 53 | JAG2 | JAG2 Entrez, Source | jagged 2 | 13811 | -3.102 | -0.0550 | Yes |
| 54 | NFIB | NFIB Entrez, Source | nuclear factor I/B | 13832 | -3.247 | 0.0037 | Yes |
