Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | BIOCARTA_G1_PATHWAY |
| Enrichment Score (ES) | -0.5260505 |
| Normalized Enrichment Score (NES) | -1.4174606 |
| Nominal p-value | 0.18816067 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 251 | 3.115 | 0.0892 | No |
| 2 | ABL1 | ABL1 Entrez, Source | v-abl Abelson murine leukemia viral oncogene homolog 1 | 2475 | 0.996 | -0.0369 | No |
| 3 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 2643 | 0.931 | -0.0169 | No |
| 4 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 3903 | 0.594 | -0.0872 | No |
| 5 | ATR | ATR Entrez, Source | ataxia telangiectasia and Rad3 related | 6089 | 0.183 | -0.2386 | No |
| 6 | SMAD4 | SMAD4 Entrez, Source | SMAD, mothers against DPP homolog 4 (Drosophila) | 7753 | -0.076 | -0.3560 | No |
| 7 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 8526 | -0.203 | -0.4047 | No |
| 8 | ATM | ATM Entrez, Source | ataxia telangiectasia mutated (includes complementation groups A, C and D) | 8574 | -0.209 | -0.4009 | No |
| 9 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 9191 | -0.310 | -0.4347 | No |
| 10 | TFDP1 | TFDP1 Entrez, Source | transcription factor Dp-1 | 9876 | -0.426 | -0.4693 | No |
| 11 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 10663 | -0.567 | -0.5065 | Yes |
| 12 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 10853 | -0.609 | -0.4992 | Yes |
| 13 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 11080 | -0.664 | -0.4926 | Yes |
| 14 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 11216 | -0.699 | -0.4783 | Yes |
| 15 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 11614 | -0.812 | -0.4789 | Yes |
| 16 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 11808 | -0.868 | -0.4629 | Yes |
| 17 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 12296 | -1.048 | -0.4620 | Yes |
| 18 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 12519 | -1.145 | -0.4385 | Yes |
| 19 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 12531 | -1.154 | -0.3995 | Yes |
| 20 | HDAC1 | HDAC1 Entrez, Source | histone deacetylase 1 | 13128 | -1.536 | -0.3896 | Yes |
| 21 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 13219 | -1.632 | -0.3399 | Yes |
| 22 | SKP2 | SKP2 Entrez, Source | S-phase kinase-associated protein 2 (p45) | 13366 | -1.817 | -0.2878 | Yes |
| 23 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 13368 | -1.819 | -0.2252 | Yes |
| 24 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 13611 | -2.253 | -0.1650 | Yes |
| 25 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 13734 | -2.674 | -0.0817 | Yes |
| 26 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13737 | -2.681 | 0.0105 | Yes |
