Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 4hr |
| GeneSet | BIOCARTA_P53HYPOXIA_PATHWAY |
| Enrichment Score (ES) | 0.6534971 |
| Normalized Enrichment Score (NES) | 1.9530824 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.22913495 |
| FWER p-Value | 0.212 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MDM2 | MDM2 Entrez, Source | Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) | 87 | 3.712 | 0.1281 | Yes |
| 2 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 251 | 3.115 | 0.2290 | Yes |
| 3 | NFKBIB | NFKBIB Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 302 | 2.991 | 0.3337 | Yes |
| 4 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 698 | 2.302 | 0.3885 | Yes |
| 5 | CSNK1A1 | CSNK1A1 Entrez, Source | casein kinase 1, alpha 1 | 925 | 2.048 | 0.4463 | Yes |
| 6 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 960 | 2.009 | 0.5166 | Yes |
| 7 | HSPA1A | HSPA1A Entrez, Source | heat shock 70kDa protein 1A | 1071 | 1.903 | 0.5775 | Yes |
| 8 | BAX | BAX Entrez, Source | BCL2-associated X protein | 1267 | 1.728 | 0.6260 | Yes |
| 9 | CSNK1D | CSNK1D Entrez, Source | casein kinase 1, delta | 1612 | 1.446 | 0.6535 | Yes |
| 10 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 2505 | 0.985 | 0.6248 | No |
| 11 | TAF1 | TAF1 Entrez, Source | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 4651 | 0.431 | 0.4857 | No |
| 12 | MAPK8 | MAPK8 Entrez, Source | mitogen-activated protein kinase 8 | 5109 | 0.346 | 0.4652 | No |
| 13 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 6230 | 0.162 | 0.3903 | No |
| 14 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 8467 | -0.191 | 0.2360 | No |
| 15 | ATM | ATM Entrez, Source | ataxia telangiectasia mutated (includes complementation groups A, C and D) | 8574 | -0.209 | 0.2359 | No |
| 16 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 10974 | -0.639 | 0.0860 | No |
| 17 | RPA1 | RPA1 Entrez, Source | replication protein A1, 70kDa | 11864 | -0.888 | 0.0540 | No |
| 18 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 12519 | -1.145 | 0.0483 | No |
| 19 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 12950 | -1.382 | 0.0673 | No |
