Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 4hr |
| GeneSet | BIOCARTA_RELA_PATHWAY |
| Enrichment Score (ES) | 0.6491462 |
| Normalized Enrichment Score (NES) | 1.9189339 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.18517037 |
| FWER p-Value | 0.212 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 98 | 3.658 | 0.1786 | Yes |
| 2 | RIPK1 | RIPK1 Entrez, Source | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 119 | 3.562 | 0.3579 | Yes |
| 3 | IKBKG | IKBKG Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 449 | 2.686 | 0.4705 | Yes |
| 4 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 717 | 2.272 | 0.5665 | Yes |
| 5 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 975 | 1.993 | 0.6491 | Yes |
| 6 | TRAF6 | TRAF6 Entrez, Source | TNF receptor-associated factor 6 | 2319 | 1.066 | 0.6064 | No |
| 7 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 2518 | 0.974 | 0.6416 | No |
| 8 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 4259 | 0.513 | 0.5421 | No |
| 9 | IKBKB | IKBKB Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 5155 | 0.338 | 0.4948 | No |
| 10 | CHUK | CHUK Entrez, Source | conserved helix-loop-helix ubiquitous kinase | 7307 | -0.006 | 0.3400 | No |
| 11 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 9174 | -0.308 | 0.2210 | No |
| 12 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 9409 | -0.346 | 0.2217 | No |
| 13 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 10625 | -0.558 | 0.1624 | No |
| 14 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 10974 | -0.639 | 0.1698 | No |
| 15 | HDAC3 | HDAC3 Entrez, Source | histone deacetylase 3 | 11512 | -0.786 | 0.1710 | No |
