Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 4hr |
| GeneSet | KEGG_MTOR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.45029625 |
| Normalized Enrichment Score (NES) | 1.7349988 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.20992547 |
| FWER p-Value | 0.445 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RPS6KA3 | RPS6KA3 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 108 | 3.622 | 0.0628 | Yes |
| 2 | RHEB | RHEB Entrez, Source | Ras homolog enriched in brain | 244 | 3.130 | 0.1140 | Yes |
| 3 | BRAF | BRAF Entrez, Source | v-raf murine sarcoma viral oncogene homolog B1 | 281 | 3.037 | 0.1705 | Yes |
| 4 | FIGF | FIGF Entrez, Source | c-fos induced growth factor (vascular endothelial growth factor D) | 457 | 2.670 | 0.2099 | Yes |
| 5 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 698 | 2.302 | 0.2374 | Yes |
| 6 | RPS6KA1 | RPS6KA1 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 711 | 2.277 | 0.2809 | Yes |
| 7 | PIK3CD | PIK3CD Entrez, Source | phosphoinositide-3-kinase, catalytic, delta polypeptide | 795 | 2.181 | 0.3174 | Yes |
| 8 | PRKAA1 | PRKAA1 Entrez, Source | protein kinase, AMP-activated, alpha 1 catalytic subunit | 854 | 2.116 | 0.3544 | Yes |
| 9 | ULK1 | ULK1 Entrez, Source | unc-51-like kinase 1 (C. elegans) | 1012 | 1.961 | 0.3813 | Yes |
| 10 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 1095 | 1.884 | 0.4121 | Yes |
| 11 | RPS6KB1 | RPS6KB1 Entrez, Source | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 1409 | 1.605 | 0.4207 | Yes |
| 12 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 1428 | 1.585 | 0.4503 | Yes |
| 13 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 1933 | 1.255 | 0.4383 | No |
| 14 | EIF4EBP1 | EIF4EBP1 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 1 | 2415 | 1.024 | 0.4235 | No |
| 15 | PDPK1 | PDPK1 Entrez, Source | 3-phosphoinositide dependent protein kinase-1 | 2464 | 1.000 | 0.4396 | No |
| 16 | PIK3R5 | PIK3R5 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 5, p101 | 2574 | 0.954 | 0.4503 | No |
| 17 | RPS6KA6 | RPS6KA6 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 3632 | 0.659 | 0.3868 | No |
| 18 | AKT2 | AKT2 Entrez, Source | v-akt murine thymoma viral oncogene homolog 2 | 5009 | 0.364 | 0.2945 | No |
| 19 | PRKAA2 | PRKAA2 Entrez, Source | protein kinase, AMP-activated, alpha 2 catalytic subunit | 5082 | 0.351 | 0.2961 | No |
| 20 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 5247 | 0.320 | 0.2905 | No |
| 21 | RPS6KA2 | RPS6KA2 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 5638 | 0.253 | 0.2672 | No |
| 22 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 6175 | 0.168 | 0.2318 | No |
| 23 | RPS6 | RPS6 Entrez, Source | ribosomal protein S6 | 6245 | 0.159 | 0.2299 | No |
| 24 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 7162 | 0.015 | 0.1640 | No |
| 25 | INS | INS Entrez, Source | insulin | 7243 | 0.004 | 0.1583 | No |
| 26 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 7460 | -0.029 | 0.1433 | No |
| 27 | TSC2 | TSC2 Entrez, Source | tuberous sclerosis 2 | 7488 | -0.033 | 0.1420 | No |
| 28 | RPS6KB2 | RPS6KB2 Entrez, Source | ribosomal protein S6 kinase, 70kDa, polypeptide 2 | 8403 | -0.182 | 0.0795 | No |
| 29 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 8916 | -0.266 | 0.0477 | No |
| 30 | CAB39 | CAB39 Entrez, Source | calcium binding protein 39 | 9768 | -0.406 | -0.0059 | No |
| 31 | ULK2 | ULK2 Entrez, Source | unc-51-like kinase 2 (C. elegans) | 10675 | -0.569 | -0.0603 | No |
| 32 | PIK3CB | PIK3CB Entrez, Source | phosphoinositide-3-kinase, catalytic, beta polypeptide | 10970 | -0.637 | -0.0691 | No |
| 33 | STK11 | STK11 Entrez, Source | serine/threonine kinase 11 | 12314 | -1.056 | -0.1455 | No |
| 34 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 12494 | -1.132 | -0.1364 | No |
| 35 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 12836 | -1.307 | -0.1356 | No |
| 36 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12941 | -1.374 | -0.1163 | No |
| 37 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 12950 | -1.382 | -0.0900 | No |
| 38 | ULK3 | ULK3 Entrez, Source | unc-51-like kinase 3 (C. elegans) | 13071 | -1.487 | -0.0697 | No |
| 39 | CAB39L | CAB39L Entrez, Source | calcium binding protein 39-like | 13093 | -1.504 | -0.0419 | No |
| 40 | EIF4E2 | EIF4E2 Entrez, Source | eukaryotic translation initiation factor 4E member 2 | 13345 | -1.786 | -0.0252 | No |
| 41 | VEGFB | VEGFB Entrez, Source | vascular endothelial growth factor B | 13837 | -3.287 | 0.0033 | No |
