Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | KEGG_PEROXISOME |
| Enrichment Score (ES) | -0.37946147 |
| Normalized Enrichment Score (NES) | -1.3991628 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 643 | 2.387 | 0.0047 | No |
| 2 | PRDX1 | PRDX1 Entrez, Source | peroxiredoxin 1 | 730 | 2.256 | 0.0468 | No |
| 3 | PEX19 | PEX19 Entrez, Source | peroxisomal biogenesis factor 19 | 1592 | 1.456 | 0.0158 | No |
| 4 | PEX3 | PEX3 Entrez, Source | peroxisomal biogenesis factor 3 | 1788 | 1.336 | 0.0304 | No |
| 5 | ABCD4 | ABCD4 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 4 | 2073 | 1.178 | 0.0351 | No |
| 6 | PEX14 | PEX14 Entrez, Source | peroxisomal biogenesis factor 14 | 2969 | 0.829 | -0.0119 | No |
| 7 | SLC27A2 | SLC27A2 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 2 | 3001 | 0.821 | 0.0035 | No |
| 8 | PEX6 | PEX6 Entrez, Source | peroxisomal biogenesis factor 6 | 3039 | 0.813 | 0.0183 | No |
| 9 | SLC25A17 | SLC25A17 Entrez, Source | solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 | 3537 | 0.679 | -0.0031 | No |
| 10 | ABCD1 | ABCD1 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 1 | 4005 | 0.568 | -0.0247 | No |
| 11 | PEX10 | PEX10 Entrez, Source | peroxisome biogenesis factor 10 | 4335 | 0.499 | -0.0378 | No |
| 12 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 4560 | 0.451 | -0.0443 | No |
| 13 | PEX16 | PEX16 Entrez, Source | peroxisomal biogenesis factor 16 | 4856 | 0.391 | -0.0573 | No |
| 14 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 4927 | 0.378 | -0.0542 | No |
| 15 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 4983 | 0.368 | -0.0503 | No |
| 16 | MVK | MVK Entrez, Source | mevalonate kinase (mevalonic aciduria) | 5231 | 0.323 | -0.0613 | No |
| 17 | CROT | CROT Entrez, Source | carnitine O-octanoyltransferase | 5316 | 0.307 | -0.0608 | No |
| 18 | NUDT12 | NUDT12 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 12 | 5487 | 0.277 | -0.0671 | No |
| 19 | CRAT | CRAT Entrez, Source | carnitine acetyltransferase | 6615 | 0.097 | -0.1465 | No |
| 20 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 6817 | 0.068 | -0.1596 | No |
| 21 | HSD17B4 | HSD17B4 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 4 | 7149 | 0.017 | -0.1832 | No |
| 22 | PIPOX | PIPOX Entrez, Source | pipecolic acid oxidase | 7524 | -0.039 | -0.2094 | No |
| 23 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 7552 | -0.043 | -0.2104 | No |
| 24 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 8071 | -0.126 | -0.2452 | No |
| 25 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 8112 | -0.132 | -0.2452 | No |
| 26 | HAO1 | HAO1 Entrez, Source | hydroxyacid oxidase (glycolate oxidase) 1 | 8177 | -0.141 | -0.2468 | No |
| 27 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 8276 | -0.161 | -0.2505 | No |
| 28 | PAOX | PAOX Entrez, Source | polyamine oxidase (exo-N4-amino) | 8371 | -0.176 | -0.2535 | No |
| 29 | ACOX3 | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 8373 | -0.176 | -0.2498 | No |
| 30 | PEX5 | PEX5 Entrez, Source | peroxisomal biogenesis factor 5 | 8985 | -0.278 | -0.2880 | No |
| 31 | PEX11A | PEX11A Entrez, Source | peroxisomal biogenesis factor 11A | 9165 | -0.307 | -0.2944 | No |
| 32 | PEX26 | PEX26 Entrez, Source | peroxisome biogenesis factor 26 | 9520 | -0.365 | -0.3121 | No |
| 33 | PEX1 | PEX1 Entrez, Source | peroxisome biogenesis factor 1 | 9778 | -0.408 | -0.3220 | No |
| 34 | HMGCL | HMGCL Entrez, Source | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) | 9785 | -0.409 | -0.3137 | No |
| 35 | GSTK1 | GSTK1 Entrez, Source | glutathione S-transferase kappa 1 | 10505 | -0.539 | -0.3541 | No |
| 36 | CAT | CAT Entrez, Source | catalase | 10737 | -0.582 | -0.3583 | No |
| 37 | DECR2 | DECR2 Entrez, Source | 2,4-dienoyl CoA reductase 2, peroxisomal | 10738 | -0.582 | -0.3458 | No |
| 38 | PEX13 | PEX13 Entrez, Source | peroxisome biogenesis factor 13 | 10965 | -0.635 | -0.3485 | No |
| 39 | PEX11G | PEX11G Entrez, Source | peroxisomal biogenesis factor 11 gamma | 10988 | -0.642 | -0.3364 | No |
| 40 | PEX12 | PEX12 Entrez, Source | peroxisomal biogenesis factor 12 | 11585 | -0.803 | -0.3622 | Yes |
| 41 | ABCD3 | ABCD3 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 3 | 11597 | -0.807 | -0.3457 | Yes |
| 42 | PXMP4 | PXMP4 Entrez, Source | peroxisomal membrane protein 4, 24kDa | 11863 | -0.888 | -0.3458 | Yes |
| 43 | IDH2 | IDH2 Entrez, Source | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 12074 | -0.958 | -0.3405 | Yes |
| 44 | ACAA1 | ACAA1 Entrez, Source | acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase) | 12088 | -0.964 | -0.3207 | Yes |
| 45 | PRDX5 | PRDX5 Entrez, Source | peroxiredoxin 5 | 12276 | -1.038 | -0.3120 | Yes |
| 46 | PMVK | PMVK Entrez, Source | phosphomevalonate kinase | 12607 | -1.190 | -0.3103 | Yes |
| 47 | AMACR | AMACR Entrez, Source | alpha-methylacyl-CoA racemase | 12782 | -1.272 | -0.2956 | Yes |
| 48 | PEX7 | PEX7 Entrez, Source | peroxisomal biogenesis factor 7 | 12863 | -1.325 | -0.2730 | Yes |
| 49 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 13030 | -1.446 | -0.2540 | Yes |
| 50 | PECR | PECR Entrez, Source | peroxisomal trans-2-enoyl-CoA reductase | 13043 | -1.460 | -0.2236 | Yes |
| 51 | DHRS4 | DHRS4 Entrez, Source | dehydrogenase/reductase (SDR family) member 4 | 13161 | -1.569 | -0.1984 | Yes |
| 52 | PEX11B | PEX11B Entrez, Source | peroxisomal biogenesis factor 11B | 13372 | -1.827 | -0.1744 | Yes |
| 53 | MPV17 | MPV17 Entrez, Source | MpV17 mitochondrial inner membrane protein | 13472 | -1.961 | -0.1395 | Yes |
| 54 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 13613 | -2.255 | -0.1012 | Yes |
| 55 | EPHX2 | EPHX2 Entrez, Source | epoxide hydrolase 2, cytoplasmic | 13690 | -2.460 | -0.0540 | Yes |
| 56 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 13821 | -3.164 | 0.0045 | Yes |
