Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | PID_ECADHERIN_KERATINOCYTE_PATHWAY |
| Enrichment Score (ES) | -0.49638492 |
| Normalized Enrichment Score (NES) | -1.4052495 |
| Nominal p-value | 0.09643606 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 1796 | 1.333 | -0.0561 | No |
| 2 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 1943 | 1.249 | 0.0021 | No |
| 3 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2652 | 0.928 | 0.0022 | No |
| 4 | SRC | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 4410 | 0.482 | -0.0980 | No |
| 5 | AKT2 | AKT2 Entrez, Source | v-akt murine thymoma viral oncogene homolog 2 | 5009 | 0.364 | -0.1211 | No |
| 6 | ZYX | ZYX Entrez, Source | zyxin | 5468 | 0.280 | -0.1386 | No |
| 7 | VASP | VASP Entrez, Source | vasodilator-stimulated phosphoprotein | 7804 | -0.083 | -0.3025 | No |
| 8 | CTNNA1 | CTNNA1 Entrez, Source | catenin (cadherin-associated protein), alpha 1, 102kDa | 8176 | -0.141 | -0.3215 | No |
| 9 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 8916 | -0.266 | -0.3601 | No |
| 10 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 9766 | -0.405 | -0.3991 | No |
| 11 | PIP5K1A | PIP5K1A Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 9780 | -0.408 | -0.3775 | No |
| 12 | FMN1 | FMN1 Entrez, Source | formin 1 | 11084 | -0.665 | -0.4349 | No |
| 13 | CTNND1 | CTNND1 Entrez, Source | catenin (cadherin-associated protein), delta 1 | 11938 | -0.912 | -0.4461 | Yes |
| 14 | JUP | JUP Entrez, Source | junction plakoglobin | 12291 | -1.046 | -0.4139 | Yes |
| 15 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 12333 | -1.061 | -0.3584 | Yes |
| 16 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 12494 | -1.132 | -0.3076 | Yes |
| 17 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 12667 | -1.216 | -0.2530 | Yes |
| 18 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 12950 | -1.382 | -0.1972 | Yes |
| 19 | JUB | JUB Entrez, Source | jub, ajuba homolog (Xenopus laevis) | 13881 | -4.801 | 0.0001 | Yes |
