Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 0hr |
| GeneSet | REACTOME_DARPP_32_EVENTS |
| Enrichment Score (ES) | -0.65744215 |
| Normalized Enrichment Score (NES) | -1.6267698 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.735 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PDE4C | PDE4C Entrez, Source | phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila) | 2844 | 0.866 | -0.1525 | No |
| 2 | PRKAR2A | PRKAR2A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, alpha | 5223 | 0.324 | -0.3043 | No |
| 3 | PPP2CB | PPP2CB Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform | 5274 | 0.316 | -0.2888 | No |
| 4 | PRKACB | PRKACB Entrez, Source | protein kinase, cAMP-dependent, catalytic, beta | 5634 | 0.253 | -0.2992 | No |
| 5 | PPP3R1 | PPP3R1 Entrez, Source | protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I) | 5746 | 0.234 | -0.2931 | No |
| 6 | PPP3CB | PPP3CB Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) | 6493 | 0.120 | -0.3396 | No |
| 7 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 6977 | 0.042 | -0.3719 | No |
| 8 | PPP2R5D | PPP2R5D Entrez, Source | protein phosphatase 2, regulatory subunit B (B56), delta isoform | 8449 | -0.189 | -0.4665 | No |
| 9 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 8481 | -0.194 | -0.4570 | No |
| 10 | PPP2R1B | PPP2R1B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform | 8897 | -0.264 | -0.4709 | No |
| 11 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 9125 | -0.299 | -0.4691 | No |
| 12 | CALM3 | CALM3 Entrez, Source | calmodulin 3 (phosphorylase kinase, delta) | 10427 | -0.522 | -0.5312 | No |
| 13 | PRKACA | PRKACA Entrez, Source | protein kinase, cAMP-dependent, catalytic, alpha | 10715 | -0.578 | -0.5168 | No |
| 14 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 12666 | -1.216 | -0.5835 | Yes |
| 15 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 12778 | -1.270 | -0.5144 | Yes |
| 16 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 12996 | -1.414 | -0.4441 | Yes |
| 17 | PPP2R1A | PPP2R1A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 13015 | -1.428 | -0.3586 | Yes |
| 18 | PRKAR1B | PRKAR1B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, beta | 13052 | -1.467 | -0.2720 | Yes |
| 19 | CALM1 | CALM1 Entrez, Source | calmodulin 1 (phosphorylase kinase, delta) | 13125 | -1.532 | -0.1840 | Yes |
| 20 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 13385 | -1.839 | -0.0909 | Yes |
| 21 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 13543 | -2.086 | 0.0245 | Yes |
