Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 4hr |
| GeneSet | REACTOME_REGULATION_OF_APOPTOSIS |
| Enrichment Score (ES) | 0.6735405 |
| Normalized Enrichment Score (NES) | 1.7264287 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.20369905 |
| FWER p-Value | 0.445 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PSMD12 | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 2 | 4.607 | 0.0528 | Yes |
| 2 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 61 | 3.865 | 0.0930 | Yes |
| 3 | PSMC6 | PSMC6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 75 | 3.789 | 0.1356 | Yes |
| 4 | PSMC1 | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 150 | 3.390 | 0.1692 | Yes |
| 5 | PSMD13 | PSMD13 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 157 | 3.371 | 0.2075 | Yes |
| 6 | PSMA1 | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 179 | 3.312 | 0.2440 | Yes |
| 7 | UNC5B | UNC5B Entrez, Source | unc-5 homolog B (C. elegans) | 206 | 3.218 | 0.2791 | Yes |
| 8 | PSMA3 | PSMA3 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 3 | 310 | 2.978 | 0.3059 | Yes |
| 9 | PSMA6 | PSMA6 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 6 | 370 | 2.828 | 0.3341 | Yes |
| 10 | PSMD3 | PSMD3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 408 | 2.761 | 0.3631 | Yes |
| 11 | PSMC2 | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 426 | 2.730 | 0.3933 | Yes |
| 12 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 460 | 2.661 | 0.4215 | Yes |
| 13 | PSMD14 | PSMD14 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 523 | 2.561 | 0.4464 | Yes |
| 14 | PSMD1 | PSMD1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 531 | 2.546 | 0.4752 | Yes |
| 15 | PSMB1 | PSMB1 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 1 | 586 | 2.470 | 0.4996 | Yes |
| 16 | PSMA2 | PSMA2 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 2 | 728 | 2.260 | 0.5154 | Yes |
| 17 | PSMB7 | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 735 | 2.250 | 0.5408 | Yes |
| 18 | PSME4 | PSME4 Entrez, Source | proteasome (prosome, macropain) activator subunit 4 | 785 | 2.201 | 0.5626 | Yes |
| 19 | PSMB5 | PSMB5 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 5 | 1053 | 1.919 | 0.5653 | Yes |
| 20 | PSMB4 | PSMB4 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 4 | 1111 | 1.870 | 0.5827 | Yes |
| 21 | PSMD6 | PSMD6 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 1139 | 1.840 | 0.6019 | Yes |
| 22 | PSMA4 | PSMA4 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 4 | 1165 | 1.813 | 0.6209 | Yes |
| 23 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 1352 | 1.644 | 0.6263 | Yes |
| 24 | DAPK2 | DAPK2 Entrez, Source | death-associated protein kinase 2 | 1373 | 1.630 | 0.6436 | Yes |
| 25 | PSMB2 | PSMB2 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 2 | 1548 | 1.484 | 0.6481 | Yes |
| 26 | PSMD11 | PSMD11 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 1587 | 1.458 | 0.6621 | Yes |
| 27 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 1654 | 1.411 | 0.6735 | Yes |
| 28 | PSMD7 | PSMD7 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) | 2099 | 1.169 | 0.6549 | No |
| 29 | PSMA5 | PSMA5 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 5 | 2330 | 1.059 | 0.6504 | No |
| 30 | PSMD9 | PSMD9 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | 2504 | 0.985 | 0.6492 | No |
| 31 | PSMF1 | PSMF1 Entrez, Source | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 3116 | 0.792 | 0.6142 | No |
| 32 | PSMB3 | PSMB3 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 3 | 3378 | 0.721 | 0.6036 | No |
| 33 | PSMA7 | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 3394 | 0.717 | 0.6107 | No |
| 34 | DAPK3 | DAPK3 Entrez, Source | death-associated protein kinase 3 | 3412 | 0.712 | 0.6177 | No |
| 35 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 3476 | 0.695 | 0.6211 | No |
| 36 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 4051 | 0.561 | 0.5861 | No |
| 37 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 4177 | 0.533 | 0.5832 | No |
| 38 | PSMB6 | PSMB6 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 6 | 4405 | 0.483 | 0.5723 | No |
| 39 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 4571 | 0.449 | 0.5655 | No |
| 40 | PSMD4 | PSMD4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 4807 | 0.400 | 0.5531 | No |
| 41 | PAK2 | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 4882 | 0.386 | 0.5522 | No |
| 42 | PSMC5 | PSMC5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 5322 | 0.306 | 0.5240 | No |
| 43 | PSMD10 | PSMD10 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 8833 | -0.253 | 0.2732 | No |
| 44 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 8883 | -0.262 | 0.2727 | No |
| 45 | PSMD5 | PSMD5 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | 8933 | -0.269 | 0.2722 | No |
| 46 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 10352 | -0.508 | 0.1755 | No |
| 47 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 12500 | -1.134 | 0.0334 | No |
| 48 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 12569 | -1.172 | 0.0419 | No |
| 49 | MAGED1 | MAGED1 Entrez, Source | melanoma antigen family D, 1 | 13457 | -1.938 | 0.0001 | No |
| 50 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 13732 | -2.668 | 0.0109 | No |
