| Dataset | data_collapsed_to_symbols.class.cls #4hr_versus_0hr.class.cls #4hr_versus_0hr_repos |
| Phenotype | class.cls#4hr_versus_0hr_repos |
| Upregulated in class | 4hr |
| GeneSet | SIG_CD40PATHWAYMAP |
| Enrichment Score (ES) | 0.52692133 |
| Normalized Enrichment Score (NES) | 1.8155397 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.2545783 |
| FWER p-Value | 0.296 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NFKBIB | NFKBIB Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 302 | 2.991 | 0.0767 | Yes |
| 2 | NFKBIE | NFKBIE Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 434 | 2.713 | 0.1565 | Yes |
| 3 | IKBKG | IKBKG Entrez,  Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 449 | 2.686 | 0.2439 | Yes |
| 4 | PIK3CD | PIK3CD Entrez,  Source | phosphoinositide-3-kinase, catalytic, delta polypeptide | 795 | 2.181 | 0.2908 | Yes |
| 5 | MAP2K4 | MAP2K4 Entrez,  Source | mitogen-activated protein kinase kinase 4 | 1016 | 1.957 | 0.3394 | Yes |
| 6 | TRAF3 | TRAF3 Entrez,  Source | TNF receptor-associated factor 3 | 1089 | 1.893 | 0.3965 | Yes |
| 7 | DUSP1 | DUSP1 Entrez,  Source | dual specificity phosphatase 1 | 1329 | 1.670 | 0.4342 | Yes |
| 8 | MAPKAPK5 | MAPKAPK5 Entrez,  Source | mitogen-activated protein kinase-activated protein kinase 5 | 1557 | 1.476 | 0.4664 | Yes |
| 9 | NFKBIL1 | NFKBIL1 Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | 1861 | 1.302 | 0.4874 | Yes |
| 10 | MAPK12 | MAPK12 Entrez,  Source | mitogen-activated protein kinase 12 | 2186 | 1.135 | 0.5014 | Yes |
| 11 | TRAF6 | TRAF6 Entrez,  Source | TNF receptor-associated factor 6 | 2319 | 1.066 | 0.5269 | Yes |
| 12 | NFKB2 | NFKB2 Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 2857 | 0.863 | 0.5166 | No |
| 13 | CD40 | CD40 Entrez,  Source | CD40 molecule, TNF receptor superfamily member 5 | 3844 | 0.609 | 0.4654 | No |
| 14 | MAPK11 | MAPK11 Entrez,  Source | mitogen-activated protein kinase 11 | 4726 | 0.414 | 0.4155 | No |
| 15 | MAPK8 | MAPK8 Entrez,  Source | mitogen-activated protein kinase 8 | 5109 | 0.346 | 0.3993 | No |
| 16 | MAPK8IP3 | MAPK8IP3 Entrez,  Source | mitogen-activated protein kinase 8 interacting protein 3 | 5154 | 0.339 | 0.4073 | No |
| 17 | MAPK8IP1 | MAPK8IP1 Entrez,  Source | mitogen-activated protein kinase 8 interacting protein 1 | 5370 | 0.298 | 0.4016 | No |
| 18 | MAPK8IP2 | MAPK8IP2 Entrez,  Source | mitogen-activated protein kinase 8 interacting protein 2 | 6425 | 0.130 | 0.3298 | No |
| 19 | MAPK13 | MAPK13 Entrez,  Source | mitogen-activated protein kinase 13 | 6551 | 0.111 | 0.3244 | No |
| 20 | MAPK1 | MAPK1 Entrez,  Source | mitogen-activated protein kinase 1 | 7460 | -0.029 | 0.2598 | No |
| 21 | MAP2K7 | MAP2K7 Entrez,  Source | mitogen-activated protein kinase kinase 7 | 8590 | -0.212 | 0.1853 | No |
| 22 | PIK3CA | PIK3CA Entrez,  Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 8916 | -0.266 | 0.1706 | No |
| 23 | MAPK14 | MAPK14 Entrez,  Source | mitogen-activated protein kinase 14 | 9049 | -0.288 | 0.1705 | No |
| 24 | NFKB1 | NFKB1 Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 9174 | -0.308 | 0.1717 | No |
| 25 | GORASP1 | GORASP1 Entrez,  Source | golgi reassembly stacking protein 1, 65kDa | 9505 | -0.361 | 0.1598 | No |
| 26 | TRAF5 | TRAF5 Entrez,  Source | TNF receptor-associated factor 5 | 9730 | -0.397 | 0.1567 | No |
| 27 | MAPK9 | MAPK9 Entrez,  Source | mitogen-activated protein kinase 9 | 9767 | -0.405 | 0.1674 | No |
| 28 | NFKBIA | NFKBIA Entrez,  Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 10625 | -0.558 | 0.1239 | No |
| 29 | SYT1 | SYT1 Entrez,  Source | synaptotagmin I | 11798 | -0.867 | 0.0679 | No |
| 30 | PIK3R1 | PIK3R1 Entrez,  Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 12494 | -1.132 | 0.0550 | No |
| 31 | MAPK3 | MAPK3 Entrez,  Source | mitogen-activated protein kinase 3 | 12941 | -1.374 | 0.0680 | No |

