Details for gene set PID_P53_DOWNSTREAM_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	normalized_counts_per_kilobase_for_GSEA.class.cls #AHRR-overexpressed_versus_Control
Phenotype	class.cls#AHRR-overexpressed_versus_Control
Upregulated in class	AHRR-overexpressed
GeneSet	PID_P53_DOWNSTREAM_PATHWAY
Enrichment Score (ES)	0.45015523
Normalized Enrichment Score (NES)	1.6960099
Nominal p-value	0.0
FDR q-value	0.21744376
FWER p-Value	0.454

Fig 1: Enrichment plot: PID_P53_DOWNSTREAM_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PRDM1	na			35	2.825	0.0430	Yes
2	NLRC4	na			144	2.079	0.0700	Yes
3	MMP2	na			193	1.904	0.0976	Yes
4	BCL6	na			231	1.829	0.1247	Yes
5	VCAN	na			239	1.778	0.1526	Yes
6	JUN	na			334	1.569	0.1723	Yes
7	TGFA	na			380	1.491	0.1935	Yes
8	SESN1	na			396	1.460	0.2159	Yes
9	CASP1	na			486	1.332	0.2321	Yes
10	EPHA2	na			517	1.294	0.2510	Yes
11	DUSP1	na			626	1.188	0.2638	Yes
12	TNFRSF10D	na			782	1.063	0.2720	Yes
13	CTSD	na			786	1.061	0.2887	Yes
14	S100A2	na			855	1.010	0.3010	Yes
15	IGFBP3	na			864	1.001	0.3165	Yes
16	TNFRSF10A	na			967	0.934	0.3256	Yes
17	SPP1	na			1028	0.892	0.3364	Yes
18	PPP1R13B	na			1044	0.887	0.3497	Yes
19	TNFRSF10B	na			1062	0.880	0.3627	Yes
20	GDF15	na			1110	0.859	0.3737	Yes
21	PTEN	na			1170	0.825	0.3835	Yes
22	SNAI2	na			1171	0.823	0.3967	Yes
23	MET	na			1294	0.778	0.4022	Yes
24	DDIT4	na			1359	0.751	0.4105	Yes
25	CCNG1	na			1594	0.664	0.4079	Yes
26	TP53INP1	na			1673	0.639	0.4136	Yes
27	BID	na			1705	0.631	0.4220	Yes
28	SERPINE1	na			1710	0.630	0.4318	Yes
29	BTG2	na			1743	0.622	0.4399	Yes
30	FAS	na			1824	0.600	0.4449	Yes
31	VDR	na			1896	0.582	0.4502	Yes
32	CASP6	na			2115	0.537	0.4464	No
33	RNF144B	na			2476	0.466	0.4335	No
34	HTT	na			2486	0.465	0.4404	No
35	IRF5	na			2911	0.398	0.4228	No
36	CREBBP	na			3142	0.368	0.4157	No
37	TADA2B	na			3751	0.297	0.3861	No
38	BAK1	na			3897	0.281	0.3824	No
39	BNIP3L	na			4194	0.250	0.3697	No
40	MCL1	na			4251	0.246	0.3704	No
41	GPX1	na			4265	0.245	0.3736	No
42	APC	na			4307	0.241	0.3751	No
43	POU4F1	na			4450	0.230	0.3708	No
44	EP300	na			4523	0.225	0.3703	No
45	CCNK	na			4643	0.215	0.3670	No
46	PML	na			5033	0.186	0.3480	No
47	FOXA1	na			5052	0.184	0.3499	No
48	CARM1	na			5232	0.173	0.3426	No
49	CASP10	na			5242	0.173	0.3448	No
50	APAF1	na			5363	0.164	0.3406	No
51	TP53I3	na			5587	0.149	0.3304	No
52	BCL2A1	na			5708	0.140	0.3259	No
53	TP63	na			5786	0.136	0.3237	No
54	TP53BP2	na			6451	0.095	0.2878	No
55	E2F2	na			6489	0.093	0.2872	No
56	SCN3B	na			6705	0.082	0.2763	No
57	CCNB1	na			6949	0.068	0.2637	No
58	STEAP3	na			6968	0.067	0.2637	No
59	TRRAP	na			6973	0.066	0.2646	No
60	PMS2	na			7695	0.029	0.2243	No
61	SP1	na			7818	0.022	0.2178	No
62	TP53	na			7860	0.019	0.2158	No
63	TRIAP1	na			7938	0.015	0.2117	No
64	RB1	na			8213	0.002	0.1962	No
65	DDX5	na			8260	-0.001	0.1937	No
66	NFYA	na			8285	-0.001	0.1923	No
67	SMARCA4	na			8334	-0.004	0.1897	No
68	TSC2	na			8870	-0.030	0.1600	No
69	NDRG1	na			8871	-0.030	0.1604	No
70	RFWD2	na			9014	-0.037	0.1530	No
71	RRM2B	na			9114	-0.041	0.1481	No
72	NFYB	na			9143	-0.043	0.1472	No
73	ZNF385A	na			9437	-0.057	0.1315	No
74	PRMT1	na			9471	-0.058	0.1306	No
75	E2F3	na			9560	-0.062	0.1266	No
76	CEBPZ	na			9575	-0.063	0.1268	No
77	ARID3A	na			9584	-0.063	0.1274	No
78	BCL2L1	na			9719	-0.069	0.1209	No
79	ATF3	na			9747	-0.071	0.1205	No
80	CDKN1A	na			10829	-0.127	0.0615	No
81	MAP4K4	na			10836	-0.127	0.0632	No
82	TNFRSF10C	na			10921	-0.132	0.0606	No
83	PRKAB1	na			11377	-0.157	0.0374	No
84	DROSHA	na			11519	-0.166	0.0321	No
85	CSE1L	na			12084	-0.197	0.0034	No
86	PYCARD	na			12103	-0.198	0.0055	No
87	BDKRB2	na			12229	-0.205	0.0018	No
88	RPS27L	na			12290	-0.209	0.0017	No
89	PCBP4	na			12297	-0.209	0.0047	No
90	TAF9	na			12597	-0.226	-0.0086	No
91	KAT2A	na			12666	-0.230	-0.0088	No
92	HIC1	na			12829	-0.242	-0.0141	No
93	TAP1	na			12836	-0.242	-0.0105	No
94	BBC3	na			12933	-0.248	-0.0120	No
95	HDAC2	na			12970	-0.251	-0.0100	No
96	NFYC	na			13111	-0.261	-0.0138	No
97	BAX	na			13274	-0.273	-0.0186	No
98	BCL2L2	na			13518	-0.293	-0.0276	No
99	TFDP1	na			14006	-0.335	-0.0498	No
100	TYRP1	na			14072	-0.340	-0.0480	No
101	DDB2	na			14109	-0.344	-0.0446	No
102	PLK3	na			14196	-0.352	-0.0438	No
103	AIFM2	na			14235	-0.355	-0.0403	No
104	DGCR8	na			14402	-0.370	-0.0438	No
105	DUSP5	na			14499	-0.380	-0.0432	No
106	MLH1	na			14623	-0.392	-0.0438	No
107	PPM1J	na			14907	-0.424	-0.0531	No
108	PCNA	na			14965	-0.429	-0.0495	No
109	MSH2	na			15206	-0.455	-0.0558	No
110	RCHY1	na			15233	-0.459	-0.0499	No
111	GADD45A	na			15344	-0.474	-0.0486	No
112	FDXR	na			15695	-0.527	-0.0599	No
113	PERP	na			15852	-0.550	-0.0600	No
114	JMY	na			16127	-0.600	-0.0659	No
115	MDM2	na			16337	-0.647	-0.0674	No
116	HGF	na			16852	-0.804	-0.0836	No
117	E2F1	na			16952	-0.845	-0.0757	No
118	BCL2	na			17015	-0.875	-0.0653	No
119	CD82	na			17114	-0.921	-0.0561	No
120	PMAIP1	na			17141	-0.940	-0.0426	No
121	TP73	na			17450	-1.173	-0.0413	No
122	COL18A1	na			17487	-1.203	-0.0242	No
123	CAV1	na			17617	-1.372	-0.0096	No
124	POU4F2	na			17626	-1.395	0.0121	No

Fig 2: PID_P53_DOWNSTREAM_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: PID_P53_DOWNSTREAM_PATHWAY: Random ES distribution   
Gene set null distribution of ES for PID_P53_DOWNSTREAM_PATHWAY