Details for gene set REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS[GSEA]

Table: GSEA Results Summary

Dataset	normalized_counts_per_kilobase_for_GSEA.class.cls #AHRR-overexpressed_versus_Control
Phenotype	class.cls#AHRR-overexpressed_versus_Control
Upregulated in class	Control
GeneSet	REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS
Enrichment Score (ES)	-0.49406242
Normalized Enrichment Score (NES)	-1.3940719
Nominal p-value	0.022075055
FDR q-value	1.0
FWER p-Value	0.991

Fig 1: Enrichment plot: REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	BID	na			1705	0.631	0.0109	No
2	BMF	na			3476	0.325	-0.0334	No
3	YWHAB	na			5668	0.144	-0.1320	No
4	TP53	na			7860	0.019	-0.2517	No
5	PPP3R1	na			8858	-0.029	-0.3028	No
6	DYNLL1	na			10217	-0.095	-0.3629	No
7	BAD	na			10799	-0.125	-0.3744	No
8	BBC3	na			12933	-0.248	-0.4522	Yes
9	AKT1	na			13100	-0.260	-0.4177	Yes
10	TFDP1	na			14006	-0.335	-0.4119	Yes
11	BCL2L11	na			14091	-0.341	-0.3590	Yes
12	MAPK8	na			14101	-0.343	-0.3016	Yes
13	DYNLL2	na			14385	-0.368	-0.2553	Yes
14	E2F1	na			16952	-0.845	-0.2566	Yes
15	BCL2	na			17015	-0.875	-0.1124	Yes
16	PMAIP1	na			17141	-0.940	0.0393	Yes

Fig 2: REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS: Random ES distribution   
Gene set null distribution of ES for REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS