Details for gene set REACTOME_DIABETES_PATHWAYS[GSEA]

Table: GSEA Results Summary

Dataset	normalized_counts_per_kilobase_for_GSEA.class.cls #AHRR-overexpressed_versus_Control
Phenotype	class.cls#AHRR-overexpressed_versus_Control
Upregulated in class	AHRR-overexpressed
GeneSet	REACTOME_DIABETES_PATHWAYS
Enrichment Score (ES)	0.44242266
Normalized Enrichment Score (NES)	1.680366
Nominal p-value	0.0
FDR q-value	0.23661625
FWER p-Value	0.534

Fig 1: Enrichment plot: REACTOME_DIABETES_PATHWAYS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IGFBP5	na			25	3.002	0.0672	Yes
2	MMP2	na			193	1.904	0.1013	Yes
3	PLA2G7	na			422	1.420	0.1209	Yes
4	WIPI1	na			459	1.371	0.1502	Yes
5	WFS1	na			480	1.347	0.1798	Yes
6	TSPYL2	na			820	1.036	0.1844	Yes
7	IGFBP3	na			864	1.001	0.2048	Yes
8	CCL2	na			922	0.973	0.2238	Yes
9	HERPUD1	na			932	0.961	0.2453	Yes
10	HSPA5	na			1060	0.881	0.2583	Yes
11	FKBP14	na			1151	0.835	0.2723	Yes
12	PDIA6	na			1319	0.768	0.2804	Yes
13	HYOU1	na			1356	0.751	0.2955	Yes
14	DNAJC3	na			1413	0.727	0.3090	Yes
15	SEC31A	na			1427	0.723	0.3248	Yes
16	MMP1	na			1569	0.673	0.3322	Yes
17	PPP2R5B	na			1619	0.658	0.3445	Yes
18	EXTL3	na			1835	0.596	0.3460	Yes
19	DNAJB9	na			1989	0.562	0.3502	Yes
20	SYVN1	na			1992	0.561	0.3629	Yes
21	IGF2BP3	na			2004	0.558	0.3750	Yes
22	DNAJB11	na			2076	0.544	0.3834	Yes
23	EIF2AK3	na			2089	0.541	0.3951	Yes
24	HSP90B1	na			2096	0.541	0.4071	Yes
25	TLN1	na			2329	0.494	0.4053	Yes
26	CPE	na			2509	0.460	0.4058	Yes
27	SSR1	na			2714	0.425	0.4040	Yes
28	SERP1	na			2843	0.408	0.4061	Yes
29	SEC11C	na			3021	0.382	0.4048	Yes
30	IGFALS	na			3074	0.375	0.4105	Yes
31	SPCS3	na			3076	0.375	0.4190	Yes
32	IGFBP6	na			3099	0.373	0.4263	Yes
33	ATP6V0D1	na			3256	0.352	0.4255	Yes
34	MBOAT4	na			3480	0.325	0.4204	Yes
35	MYO5A	na			3535	0.320	0.4246	Yes
36	GOSR2	na			3671	0.304	0.4240	Yes
37	ATF6	na			3701	0.302	0.4292	Yes
38	EXOC2	na			3785	0.293	0.4312	Yes
39	SEC11A	na			3794	0.292	0.4375	Yes
40	DDIT3	na			3999	0.271	0.4321	Yes
41	KDELR3	na			4065	0.264	0.4345	Yes
42	ADD1	na			4090	0.261	0.4391	Yes
43	SHC1	na			4136	0.256	0.4424	Yes
44	TPP1	na			4665	0.213	0.4175	No
45	PARN	na			4791	0.204	0.4151	No
46	KLF4	na			5097	0.182	0.4021	No
47	MBTPS2	na			5225	0.174	0.3989	No
48	CTDSP2	na			5359	0.164	0.3951	No
49	EDEM1	na			5391	0.162	0.3971	No
50	LMNA	na			5550	0.151	0.3916	No
51	PDIA5	na			5561	0.150	0.3945	No
52	DCP2	na			5563	0.150	0.3978	No
53	F2	na			5624	0.147	0.3978	No
54	YIF1A	na			5699	0.141	0.3969	No
55	ARFGAP1	na			5743	0.138	0.3976	No
56	HDGF	na			5795	0.135	0.3978	No
57	SLC30A5	na			5843	0.132	0.3982	No
58	STX1A	na			6048	0.119	0.3894	No
59	CUL7	na			6418	0.097	0.3708	No
60	DIS3	na			6509	0.092	0.3678	No
61	SNAP25	na			6857	0.073	0.3499	No
62	EXOC4	na			6864	0.073	0.3512	No
63	EXOC8	na			6882	0.071	0.3519	No
64	TATDN2	na			7292	0.050	0.3300	No
65	CALR	na			7531	0.038	0.3174	No
66	SRPRB	na			7573	0.035	0.3159	No
67	DCTN1	na			7927	0.016	0.2964	No
68	EIF2S1	na			7989	0.013	0.2932	No
69	KHSRP	na			8076	0.008	0.2886	No
70	PAPPA2	na			8195	0.003	0.2820	No
71	NFYA	na			8285	-0.001	0.2770	No
72	EXOC5	na			8576	-0.016	0.2610	No
73	XBP1	na			8800	-0.026	0.2490	No
74	RAB27A	na			9100	-0.041	0.2331	No
75	NFYB	na			9143	-0.043	0.2317	No
76	SLC30A7	na			9146	-0.043	0.2325	No
77	KIF5B	na			9332	-0.052	0.2233	No
78	MBTPS1	na			9449	-0.057	0.2181	No
79	ATF3	na			9747	-0.071	0.2030	No
80	ERN1	na			9953	-0.082	0.1933	No
81	ATF4	na			9968	-0.083	0.1944	No
82	EXOC1	na			10123	-0.091	0.1878	No
83	EXOSC6	na			10327	-0.100	0.1786	No
84	SPCS2	na			10418	-0.106	0.1759	No
85	ACADVL	na			10752	-0.122	0.1600	No
86	GSK3A	na			11157	-0.144	0.1405	No
87	CXXC1	na			11356	-0.156	0.1329	No
88	EXOC6	na			11403	-0.159	0.1339	No
89	EXOSC3	na			11659	-0.174	0.1235	No
90	VAMP2	na			11720	-0.177	0.1242	No
91	EXOSC1	na			12232	-0.205	0.1000	No
92	IGFBP2	na			12497	-0.220	0.0902	No
93	IGF2BP2	na			12559	-0.223	0.0918	No
94	EXOSC4	na			12762	-0.237	0.0859	No
95	PREB	na			12924	-0.248	0.0824	No
96	SPCS1	na			13319	-0.278	0.0666	No
97	EXOSC2	na			13422	-0.286	0.0673	No
98	GHRL	na			13990	-0.333	0.0430	No
99	KLHDC3	na			14213	-0.353	0.0385	No
100	ZBTB17	na			14601	-0.390	0.0256	No
101	EXOSC9	na			14820	-0.414	0.0228	No
102	CTSG	na			15047	-0.438	0.0201	No
103	EXOSC7	na			15161	-0.451	0.0240	No
104	EXOSC5	na			15249	-0.462	0.0296	No
105	EXOSC8	na			16043	-0.587	-0.0017	No
106	DDX12P	na			16142	-0.603	0.0066	No
107	DDX11	na			16189	-0.611	0.0179	No
108	ASNS	na			16364	-0.653	0.0230	No
109	EXOC3	na			16527	-0.697	0.0298	No
110	IGFBP4	na			17768	-1.935	0.0041	No

Fig 2: REACTOME_DIABETES_PATHWAYS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_DIABETES_PATHWAYS: Random ES distribution   
Gene set null distribution of ES for REACTOME_DIABETES_PATHWAYS