Details for gene set REACTOME_MEMBRANE_TRAFFICKING[GSEA]

Table: GSEA Results Summary

Dataset	normalized_counts_per_kilobase_for_GSEA.class.cls #AHRR-overexpressed_versus_Control
Phenotype	class.cls#AHRR-overexpressed_versus_Control
Upregulated in class	AHRR-overexpressed
GeneSet	REACTOME_MEMBRANE_TRAFFICKING
Enrichment Score (ES)	0.43513438
Normalized Enrichment Score (NES)	1.7452687
Nominal p-value	0.0
FDR q-value	0.32199946
FWER p-Value	0.352

Fig 1: Enrichment plot: REACTOME_MEMBRANE_TRAFFICKING   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CTSZ	na			277	1.675	0.0319	Yes
2	DAB2	na			445	1.383	0.0617	Yes
3	CPD	na			601	1.221	0.0876	Yes
4	TPD52	na			770	1.077	0.1086	Yes
5	GJC2	na			840	1.018	0.1336	Yes
6	FTH1	na			991	0.915	0.1511	Yes
7	DNAJC6	na			1009	0.907	0.1759	Yes
8	TJP1	na			1103	0.863	0.1951	Yes
9	TPD52L1	na			1142	0.841	0.2168	Yes
10	SEC31A	na			1427	0.723	0.2213	Yes
11	SEC24D	na			1460	0.712	0.2396	Yes
12	SEC23A	na			1517	0.691	0.2561	Yes
13	MYO6	na			1806	0.606	0.2570	Yes
14	DNASE2	na			1892	0.583	0.2687	Yes
15	AP1B1	na			2011	0.556	0.2778	Yes
16	ARRB1	na			2014	0.556	0.2935	Yes
17	COPA	na			2058	0.547	0.3066	Yes
18	SORT1	na			2070	0.545	0.3214	Yes
19	AP3S1	na			2457	0.469	0.3129	Yes
20	CHMP2B	na			2493	0.462	0.3241	Yes
21	COPB2	na			2842	0.408	0.3160	Yes
22	FTL	na			2853	0.406	0.3270	Yes
23	VPS37A	na			2992	0.385	0.3301	Yes
24	VPS4A	na			3121	0.371	0.3334	Yes
25	SNX9	na			3241	0.354	0.3368	Yes
26	RAB5C	na			3258	0.352	0.3458	Yes
27	VPS37C	na			3274	0.350	0.3549	Yes
28	SEC13	na			3293	0.347	0.3637	Yes
29	SAR1B	na			3333	0.341	0.3712	Yes
30	IGF2R	na			3391	0.335	0.3775	Yes
31	AP4E1	na			3402	0.334	0.3864	Yes
32	COPZ1	na			3437	0.330	0.3938	Yes
33	CHMP7	na			3520	0.322	0.3983	Yes
34	ARCN1	na			3545	0.319	0.4060	Yes
35	AP3B1	na			3737	0.299	0.4037	Yes
36	AP2M1	na			3896	0.281	0.4027	Yes
37	GAK	na			3913	0.279	0.4097	Yes
38	SEC24B	na			4025	0.268	0.4111	Yes
39	NAPA	na			4046	0.266	0.4175	Yes
40	VPS37B	na			4157	0.254	0.4185	Yes
41	GJB2	na			4270	0.244	0.4191	Yes
42	CLTC	na			4328	0.240	0.4227	Yes
43	AP1G1	na			4409	0.234	0.4248	Yes
44	CHMP4C	na			4463	0.229	0.4283	Yes
45	COPB1	na			4559	0.223	0.4293	Yes
46	AP1S2	na			4619	0.217	0.4321	Yes
47	M6PR	na			4673	0.212	0.4351	Yes
48	HSPA8	na			4922	0.194	0.4266	No
49	CHMP4B	na			5341	0.165	0.4078	No
50	ARF1	na			5492	0.156	0.4037	No
51	BLOC1S3	na			5513	0.154	0.4070	No
52	CLTA	na			5711	0.140	0.3998	No
53	ARFGAP1	na			5743	0.138	0.4020	No
54	SNAPIN	na			5849	0.132	0.3998	No
55	GNS	na			5903	0.128	0.4004	No
56	GBF1	na			6014	0.121	0.3977	No
57	CHMP5	na			6030	0.120	0.4002	No
58	SEC24C	na			6112	0.116	0.3989	No
59	DTNBP1	na			6262	0.106	0.3936	No
60	VPS37D	na			6264	0.106	0.3965	No
61	AP1S1	na			6277	0.105	0.3988	No
62	HIP1R	na			6403	0.098	0.3945	No
63	NECAP1	na			6474	0.094	0.3933	No
64	YIPF6	na			6496	0.093	0.3947	No
65	VAMP8	na			6546	0.090	0.3945	No
66	STAM2	na			6718	0.081	0.3871	No
67	PICALM	na			6719	0.081	0.3894	No
68	TFRC	na			6841	0.074	0.3847	No
69	GJC1	na			6863	0.073	0.3856	No
70	SNX5	na			6996	0.065	0.3800	No
71	DNM2	na			7395	0.044	0.3588	No
72	SNF8	na			7800	0.023	0.3367	No
73	STX4	na			8013	0.011	0.3250	No
74	VPS4B	na			8534	-0.014	0.2961	No
75	PIK3C2A	na			8732	-0.023	0.2856	No
76	PUM1	na			8745	-0.024	0.2856	No
77	COPE	na			8785	-0.025	0.2841	No
78	SNX2	na			8905	-0.031	0.2783	No
79	TGOLN2	na			9298	-0.051	0.2577	No
80	VPS36	na			9536	-0.061	0.2460	No
81	OCRL	na			9600	-0.064	0.2443	No
82	CHMP4A	na			9919	-0.080	0.2286	No
83	SH3D19	na			10185	-0.094	0.2163	No
84	TXNDC5	na			10255	-0.097	0.2152	No
85	VTA1	na			10355	-0.102	0.2125	No
86	CHMP2A	na			10640	-0.117	0.1998	No
87	UBA52	na			10722	-0.121	0.1986	No
88	AP4B1	na			11035	-0.137	0.1849	No
89	CHMP3	na			11110	-0.141	0.1848	No
90	VPS28	na			11148	-0.143	0.1867	No
91	GJB5	na			11389	-0.159	0.1777	No
92	TBC1D8B	na			11485	-0.164	0.1770	No
93	VPS25	na			11596	-0.170	0.1756	No
94	VAMP2	na			11720	-0.177	0.1737	No
95	HGS	na			11761	-0.179	0.1765	No
96	TSG101	na			12541	-0.222	0.1389	No
97	AP1M1	na			12696	-0.233	0.1368	No
98	SNAP23	na			12879	-0.245	0.1335	No
99	PREB	na			12924	-0.248	0.1380	No
100	RPS27A	na			12944	-0.249	0.1440	No
101	CHMP6	na			13939	-0.328	0.0973	No
102	BLOC1S1	na			14169	-0.349	0.0943	No
103	STAM	na			14618	-0.392	0.0801	No
104	CLTB	na			14720	-0.404	0.0859	No
105	SRC	na			15836	-0.548	0.0385	No
106	DNM1	na			16401	-0.659	0.0254	No
107	CLTCL1	na			16828	-0.794	0.0239	No
108	GJA3	na			17442	-1.169	0.0225	No

Fig 2: REACTOME_MEMBRANE_TRAFFICKING   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_MEMBRANE_TRAFFICKING: Random ES distribution   
Gene set null distribution of ES for REACTOME_MEMBRANE_TRAFFICKING