Details for gene set REACTOME_MEMBRANE_TRAFFICKING[GSEA]

Table: GSEA Results Summary

Dataset	normalized_counts_per_kilobase_for_GSEA_1.class_1.cls #AHRR-overexpressed_versus_Control
Phenotype	class_1.cls#AHRR-overexpressed_versus_Control
Upregulated in class	AHRR-overexpressed
GeneSet	REACTOME_MEMBRANE_TRAFFICKING
Enrichment Score (ES)	0.35536936
Normalized Enrichment Score (NES)	1.4502429
Nominal p-value	0.0
FDR q-value	0.6017875
FWER p-Value	1.0

Fig 1: Enrichment plot: REACTOME_MEMBRANE_TRAFFICKING   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	DNASE2	na			705	1.662	0.0127	Yes
2	TPD52L1	na			744	1.609	0.0613	Yes
3	GJC2	na			867	1.412	0.0990	Yes
4	TJP1	na			961	1.294	0.1346	Yes
5	GJB5	na			1199	1.072	0.1550	Yes
6	CTSZ	na			1243	1.041	0.1854	Yes
7	GJB2	na			1642	0.796	0.1881	Yes
8	DAB2	na			1643	0.796	0.2133	Yes
9	TPD52	na			1708	0.769	0.2339	Yes
10	CPD	na			2236	0.575	0.2223	Yes
11	SEC13	na			2393	0.536	0.2304	Yes
12	FTH1	na			2406	0.532	0.2465	Yes
13	DNAJC6	na			2413	0.531	0.2630	Yes
14	SEC31A	na			2633	0.476	0.2657	Yes
15	FTL	na			2749	0.451	0.2734	Yes
16	VAMP8	na			2898	0.421	0.2783	Yes
17	AP1B1	na			3117	0.379	0.2780	Yes
18	CHMP7	na			3326	0.344	0.2771	Yes
19	SEC24D	na			3339	0.343	0.2873	Yes
20	SNF8	na			3411	0.333	0.2938	Yes
21	HIP1R	na			3508	0.321	0.2985	Yes
22	COPZ1	na			3584	0.311	0.3041	Yes
23	RAB5C	na			3591	0.311	0.3136	Yes
24	NAPA	na			3604	0.309	0.3227	Yes
25	SAR1B	na			3640	0.305	0.3303	Yes
26	AP1S1	na			3842	0.282	0.3279	Yes
27	COPE	na			3988	0.267	0.3281	Yes
28	ARFGAP1	na			3996	0.267	0.3361	Yes
29	MYO6	na			4127	0.253	0.3368	Yes
30	CLTA	na			4260	0.241	0.3369	Yes
31	COPA	na			4295	0.238	0.3425	Yes
32	SEC23A	na			4410	0.228	0.3433	Yes
33	GAK	na			4635	0.210	0.3373	Yes
34	COPB2	na			4696	0.206	0.3404	Yes
35	ARRB1	na			4778	0.201	0.3422	Yes
36	AP3S1	na			4794	0.199	0.3476	Yes
37	ARF1	na			4837	0.197	0.3514	Yes
38	SORT1	na			4877	0.194	0.3554	Yes
39	GBF1	na			5213	0.171	0.3419	No
40	CHMP4B	na			5286	0.167	0.3431	No
41	PREB	na			5329	0.165	0.3459	No
42	VPS37C	na			5498	0.155	0.3413	No
43	BLOC1S3	na			5722	0.140	0.3332	No
44	VPS28	na			5728	0.140	0.3373	No
45	AP3B1	na			5790	0.136	0.3381	No
46	AP2M1	na			5877	0.130	0.3374	No
47	CHMP4A	na			6019	0.121	0.3333	No
48	VPS4A	na			6128	0.116	0.3308	No
49	CHMP2A	na			6191	0.112	0.3309	No
50	IGF2R	na			6208	0.112	0.3335	No
51	SEC24C	na			6213	0.112	0.3368	No
52	SNAPIN	na			6273	0.108	0.3369	No
53	CHMP2B	na			6282	0.108	0.3398	No
54	SNX9	na			6303	0.106	0.3421	No
55	DTNBP1	na			6305	0.106	0.3454	No
56	UBA52	na			6492	0.095	0.3379	No
57	SH3D19	na			6871	0.077	0.3190	No
58	BLOC1S1	na			6907	0.075	0.3194	No
59	ARCN1	na			6940	0.073	0.3199	No
60	HSPA8	na			6989	0.071	0.3194	No
61	AP1G1	na			7123	0.063	0.3139	No
62	VAMP2	na			7332	0.054	0.3039	No
63	VPS37B	na			7672	0.039	0.2860	No
64	DNM2	na			7737	0.036	0.2835	No
65	CLTC	na			7787	0.034	0.2818	No
66	STX4	na			7931	0.027	0.2746	No
67	VPS37A	na			8013	0.023	0.2708	No
68	AP4B1	na			8031	0.023	0.2705	No
69	M6PR	na			8129	0.019	0.2657	No
70	COPB1	na			8318	0.010	0.2554	No
71	OCRL	na			8353	0.008	0.2537	No
72	VPS25	na			8415	0.005	0.2504	No
73	AP4E1	na			8746	-0.009	0.2321	No
74	CHMP5	na			8889	-0.016	0.2246	No
75	SNX5	na			8898	-0.016	0.2246	No
76	CLTB	na			9159	-0.026	0.2108	No
77	HGS	na			9176	-0.027	0.2108	No
78	YIPF6	na			9396	-0.037	0.1996	No
79	SEC24B	na			9460	-0.041	0.1973	No
80	CHMP6	na			9640	-0.049	0.1888	No
81	VTA1	na			10066	-0.069	0.1670	No
82	SNX2	na			10185	-0.075	0.1627	No
83	SNAP23	na			10189	-0.075	0.1649	No
84	AP1M1	na			10236	-0.077	0.1647	No
85	GNS	na			10327	-0.081	0.1622	No
86	VPS36	na			10521	-0.091	0.1542	No
87	NECAP1	na			10765	-0.102	0.1437	No
88	STAM2	na			10953	-0.112	0.1367	No
89	PICALM	na			11421	-0.134	0.1146	No
90	AP1S2	na			12030	-0.168	0.0856	No
91	DNM1	na			12260	-0.181	0.0784	No
92	TSG101	na			12436	-0.193	0.0746	No
93	RPS27A	na			12562	-0.200	0.0739	No
94	TGOLN2	na			12752	-0.214	0.0700	No
95	TBC1D8B	na			12830	-0.219	0.0726	No
96	PUM1	na			12852	-0.220	0.0783	No
97	STAM	na			13113	-0.236	0.0711	No
98	VPS4B	na			13203	-0.242	0.0737	No
99	TFRC	na			13569	-0.266	0.0615	No
100	CHMP3	na			13625	-0.272	0.0670	No
101	PIK3C2A	na			14092	-0.317	0.0507	No
102	CLTCL1	na			14689	-0.381	0.0292	No
103	GJC1	na			15178	-0.451	0.0159	No
104	TXNDC5	na			15347	-0.483	0.0216	No
105	VPS37D	na			16087	-0.644	0.0003	No
106	SRC	na			16527	-0.788	0.0004	No
107	CHMP4C	na			16730	-0.885	0.0169	No
108	GJA3	na			17364	-1.447	0.0269	No

Fig 2: REACTOME_MEMBRANE_TRAFFICKING   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_MEMBRANE_TRAFFICKING: Random ES distribution   
Gene set null distribution of ES for REACTOME_MEMBRANE_TRAFFICKING