Details for gene set REACTOME_CELL_CYCLE_CHECKPOINTS[GSEA]

Table: GSEA Results Summary

Dataset	normalized_counts_per_kilobase_for_GSEA_2.class_2.cls #AHRR-overexpressed_versus_Control
Phenotype	class_2.cls#AHRR-overexpressed_versus_Control
Upregulated in class	Control
GeneSet	REACTOME_CELL_CYCLE_CHECKPOINTS
Enrichment Score (ES)	-0.28904969
Normalized Enrichment Score (NES)	-1.433504
Nominal p-value	0.0
FDR q-value	1.0
FWER p-Value	1.0

Fig 1: Enrichment plot: REACTOME_CELL_CYCLE_CHECKPOINTS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	UBE2D1	na			2479	0.452	-0.1077	No
2	PSMC4	na			3303	0.317	-0.1316	No
3	CDKN1A	na			3668	0.274	-0.1327	No
4	PSMD3	na			4285	0.218	-0.1520	No
5	PSMD5	na			4354	0.213	-0.1407	No
6	PSMA6	na			5023	0.164	-0.1667	No
7	ANAPC1	na			5378	0.144	-0.1765	No
8	UBE2E1	na			5697	0.129	-0.1853	No
9	PSMD11	na			5771	0.125	-0.1805	No
10	PSMF1	na			5807	0.123	-0.1738	No
11	CDC27	na			5924	0.117	-0.1721	No
12	ATM	na			6065	0.109	-0.1722	No
13	PSME4	na			6203	0.103	-0.1726	No
14	PSMA1	na			6253	0.101	-0.1682	No
15	PSMD2	na			6562	0.087	-0.1794	No
16	ANAPC4	na			6666	0.083	-0.1793	No
17	PSMB5	na			6774	0.078	-0.1798	No
18	PSMA4	na			6778	0.078	-0.1745	No
19	HUS1	na			6830	0.075	-0.1720	No
20	RFC2	na			6913	0.071	-0.1716	No
21	PSMC2	na			7024	0.067	-0.1731	No
22	ATR	na			7102	0.064	-0.1729	No
23	PSMD14	na			7127	0.063	-0.1697	No
24	MCM8	na			7144	0.062	-0.1662	No
25	ORC2	na			7216	0.059	-0.1660	No
26	PSMC1	na			7256	0.058	-0.1641	No
27	PSMD6	na			7286	0.057	-0.1617	No
28	PSMD1	na			7413	0.052	-0.1651	No
29	CDC16	na			7493	0.049	-0.1661	No
30	CDC26	na			7581	0.045	-0.1678	No
31	ANAPC7	na			7770	0.038	-0.1757	No
32	RFC3	na			7865	0.034	-0.1786	No
33	PSMD13	na			7900	0.033	-0.1782	No
34	PSMD10	na			7967	0.031	-0.1797	No
35	CDC25A	na			8116	0.025	-0.1863	No
36	PSMA5	na			8336	0.017	-0.1975	No
37	ORC5	na			8364	0.015	-0.1979	No
38	DBF4	na			8392	0.014	-0.1984	No
39	RPA2	na			8398	0.014	-0.1977	No
40	PSMD7	na			8515	0.009	-0.2036	No
41	CDKN1B	na			8605	0.006	-0.2082	No
42	PSMD8	na			8705	0.002	-0.2136	No
43	PSMC6	na			8715	0.002	-0.2140	No
44	PSMD4	na			8737	0.001	-0.2151	No
45	ORC3	na			8813	-0.002	-0.2192	No
46	ANAPC5	na			8844	-0.003	-0.2207	No
47	ANAPC10	na			8927	-0.007	-0.2248	No
48	CCNB1	na			9059	-0.011	-0.2314	No
49	ATRIP	na			9146	-0.014	-0.2353	No
50	PSME1	na			9304	-0.020	-0.2427	No
51	RFWD2	na			9330	-0.022	-0.2425	No
52	PSMB6	na			9385	-0.024	-0.2439	No
53	CDC20	na			9489	-0.028	-0.2477	No
54	CHEK1	na			9518	-0.029	-0.2472	No
55	CDC6	na			9800	-0.040	-0.2602	No
56	RAD1	na			9831	-0.041	-0.2590	No
57	PSMD12	na			9918	-0.044	-0.2607	No
58	CDC23	na			9974	-0.047	-0.2604	No
59	TP53	na			10180	-0.055	-0.2681	No
60	PSMB4	na			10214	-0.056	-0.2659	No
61	RAD17	na			10302	-0.059	-0.2666	No
62	PSMB2	na			10326	-0.060	-0.2636	No
63	PSME2	na			10524	-0.068	-0.2699	No
64	PSMA7	na			10589	-0.071	-0.2685	No
65	PSMB1	na			10605	-0.071	-0.2643	No
66	PSMC5	na			10658	-0.074	-0.2619	No
67	RPS27A	na			10937	-0.086	-0.2715	No
68	PSMA3	na			10972	-0.087	-0.2673	No
69	RFC4	na			11359	-0.104	-0.2817	Yes
70	ORC4	na			11403	-0.106	-0.2766	Yes
71	PSMD9	na			11564	-0.113	-0.2776	Yes
72	ANAPC2	na			11568	-0.113	-0.2697	Yes
73	PSMA2	na			11684	-0.119	-0.2678	Yes
74	MCM5	na			11718	-0.120	-0.2611	Yes
75	PSMB8	na			11730	-0.121	-0.2532	Yes
76	ORC6	na			11735	-0.121	-0.2448	Yes
77	ORC1	na			11761	-0.122	-0.2375	Yes
78	MCM3	na			11801	-0.124	-0.2309	Yes
79	CCNE1	na			11903	-0.129	-0.2275	Yes
80	PSMC3	na			12055	-0.136	-0.2264	Yes
81	MCM10	na			12056	-0.136	-0.2167	Yes
82	PSMB7	na			12106	-0.138	-0.2097	Yes
83	RPA1	na			12156	-0.142	-0.2024	Yes
84	BUB1B	na			12177	-0.142	-0.1934	Yes
85	PSMB3	na			12273	-0.148	-0.1883	Yes
86	RFC5	na			12490	-0.160	-0.1891	Yes
87	CDC45	na			12880	-0.182	-0.1981	Yes
88	UBA52	na			13082	-0.195	-0.1956	Yes
89	CDK1	na			13099	-0.196	-0.1825	Yes
90	MCM7	na			13111	-0.197	-0.1692	Yes
91	WEE1	na			13293	-0.209	-0.1646	Yes
92	MCM4	na			13591	-0.230	-0.1650	Yes
93	CCNE2	na			13664	-0.236	-0.1523	Yes
94	MCM6	na			13731	-0.241	-0.1389	Yes
95	MAD1L1	na			13816	-0.249	-0.1260	Yes
96	BUB3	na			13970	-0.260	-0.1161	Yes
97	CDC25C	na			14021	-0.265	-0.1001	Yes
98	CDC7	na			14050	-0.269	-0.0826	Yes
99	CCNB2	na			14159	-0.278	-0.0690	Yes
100	CDK2	na			14296	-0.292	-0.0559	Yes
101	RAD9A	na			14331	-0.297	-0.0368	Yes
102	MAD2L1	na			14492	-0.313	-0.0236	Yes
103	RPA3	na			14591	-0.326	-0.0060	Yes
104	CHEK2	na			14642	-0.332	0.0147	Yes
105	MDM2	na			14841	-0.354	0.0287	Yes
106	ANAPC11	na			14917	-0.366	0.0505	Yes
107	UBE2C	na			14965	-0.373	0.0743	Yes
108	MCM2	na			15059	-0.385	0.0964	Yes
109	PSMB10	na			15077	-0.388	0.1230	Yes
110	PSMB9	na			15528	-0.462	0.1304	Yes

Fig 2: REACTOME_CELL_CYCLE_CHECKPOINTS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_CELL_CYCLE_CHECKPOINTS: Random ES distribution   
Gene set null distribution of ES for REACTOME_CELL_CYCLE_CHECKPOINTS