Details for gene set REACTOME_DNA_REPAIR[GSEA]

Table: GSEA Results Summary

Dataset	normalized_counts_per_kilobase_for_GSEA_2.class_2.cls #AHRR-overexpressed_versus_Control
Phenotype	class_2.cls#AHRR-overexpressed_versus_Control
Upregulated in class	Control
GeneSet	REACTOME_DNA_REPAIR
Enrichment Score (ES)	-0.33330128
Normalized Enrichment Score (NES)	-1.3619545
Nominal p-value	0.18197279
FDR q-value	1.0
FWER p-Value	1.0

Fig 1: Enrichment plot: REACTOME_DNA_REPAIR   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	LIG4	na			2724	0.408	-0.1283	No
2	DDB1	na			3316	0.314	-0.1422	No
3	CCNH	na			3991	0.243	-0.1652	No
4	MBD4	na			4244	0.221	-0.1658	No
5	REV3L	na			4312	0.216	-0.1562	No
6	ERCC4	na			4386	0.210	-0.1474	No
7	XPC	na			4538	0.198	-0.1437	No
8	POLR2B	na			4728	0.185	-0.1429	No
9	ERCC8	na			4772	0.182	-0.1341	No
10	RAD23B	na			5477	0.139	-0.1652	No
11	CDK7	na			5509	0.138	-0.1584	No
12	GTF2H2	na			5784	0.124	-0.1662	No
13	XRCC6	na			6046	0.110	-0.1741	No
14	ATM	na			6065	0.109	-0.1684	No
15	XPA	na			6085	0.108	-0.1627	No
16	NBN	na			6087	0.108	-0.1561	No
17	TDG	na			6198	0.103	-0.1559	No
18	TP53BP1	na			6554	0.088	-0.1705	No
19	XRCC5	na			6678	0.082	-0.1724	No
20	ERCC3	na			6797	0.076	-0.1743	No
21	RFC2	na			6913	0.071	-0.1764	No
22	ATR	na			7102	0.064	-0.1830	No
23	POLR2A	na			7130	0.063	-0.1806	No
24	ALKBH3	na			7163	0.062	-0.1786	No
25	PRKDC	na			7220	0.059	-0.1781	No
26	ERCC5	na			7756	0.038	-0.2059	No
27	RFC3	na			7865	0.034	-0.2099	No
28	FANCM	na			8057	0.027	-0.2190	No
29	USP1	na			8099	0.026	-0.2197	No
30	POLH	na			8184	0.023	-0.2230	No
31	PALB2	na			8303	0.018	-0.2286	No
32	POLR2E	na			8326	0.017	-0.2288	No
33	RPA2	na			8398	0.014	-0.2319	No
34	FANCF	na			8839	-0.003	-0.2565	No
35	XAB2	na			9089	-0.012	-0.2698	No
36	TCEA1	na			9227	-0.017	-0.2765	No
37	TDP1	na			9333	-0.022	-0.2811	No
38	RAD52	na			9400	-0.025	-0.2833	No
39	GTF2H2B	na			9452	-0.027	-0.2845	No
40	LIG3	na			9635	-0.034	-0.2927	No
41	GTF2H1	na			9692	-0.036	-0.2936	No
42	POLD4	na			9774	-0.039	-0.2958	No
43	GTF2H3	na			9849	-0.042	-0.2974	No
44	POLD3	na			9942	-0.046	-0.2997	No
45	POLR2D	na			10089	-0.052	-0.3048	No
46	BRCA2	na			10139	-0.054	-0.3042	No
47	RAD50	na			10480	-0.066	-0.3193	No
48	SMUG1	na			10607	-0.072	-0.3220	No
49	FANCE	na			10809	-0.080	-0.3284	Yes
50	MDC1	na			10822	-0.081	-0.3240	Yes
51	ERCC1	na			10904	-0.084	-0.3234	Yes
52	XRCC4	na			10931	-0.085	-0.3196	Yes
53	RPS27A	na			10937	-0.086	-0.3146	Yes
54	POLR2G	na			11033	-0.089	-0.3145	Yes
55	REV1	na			11037	-0.089	-0.3091	Yes
56	PCNA	na			11127	-0.093	-0.3084	Yes
57	BRCA1	na			11195	-0.096	-0.3062	Yes
58	POLR2L	na			11209	-0.097	-0.3010	Yes
59	RAD51	na			11291	-0.100	-0.2994	Yes
60	RFC4	na			11359	-0.104	-0.2968	Yes
61	FANCA	na			11436	-0.107	-0.2944	Yes
62	FANCB	na			11477	-0.109	-0.2899	Yes
63	MNAT1	na			11604	-0.115	-0.2899	Yes
64	ERCC2	na			11729	-0.121	-0.2895	Yes
65	DDB2	na			11783	-0.123	-0.2848	Yes
66	POLR2C	na			11975	-0.132	-0.2875	Yes
67	RPA1	na			12156	-0.142	-0.2889	Yes
68	FANCL	na			12306	-0.149	-0.2881	Yes
69	MRE11A	na			12309	-0.149	-0.2789	Yes
70	MPG	na			12421	-0.155	-0.2756	Yes
71	RFC5	na			12490	-0.160	-0.2696	Yes
72	GTF2H4	na			12801	-0.177	-0.2761	Yes
73	POLE	na			12946	-0.186	-0.2727	Yes
74	POLR2F	na			12959	-0.187	-0.2619	Yes
75	POLR2H	na			13002	-0.190	-0.2525	Yes
76	POLR2K	na			13081	-0.195	-0.2448	Yes
77	UBA52	na			13082	-0.195	-0.2328	Yes
78	ERCC6	na			13129	-0.198	-0.2231	Yes
79	FANCD2	na			13141	-0.199	-0.2115	Yes
80	POLB	na			13394	-0.215	-0.2124	Yes
81	XRCC1	na			13455	-0.219	-0.2022	Yes
82	FEN1	na			13484	-0.222	-0.1901	Yes
83	UBE2T	na			13660	-0.236	-0.1854	Yes
84	POLE2	na			13778	-0.246	-0.1768	Yes
85	APEX1	na			13879	-0.254	-0.1668	Yes
86	POLR2J	na			13891	-0.254	-0.1517	Yes
87	OGG1	na			13904	-0.255	-0.1366	Yes
88	POLD2	na			14064	-0.270	-0.1289	Yes
89	FANCG	na			14077	-0.271	-0.1128	Yes
90	MAD2L2	na			14235	-0.284	-0.1041	Yes
91	ZBTB32	na			14362	-0.300	-0.0926	Yes
92	LIG1	na			14442	-0.308	-0.0780	Yes
93	BRIP1	na			14483	-0.312	-0.0610	Yes
94	FANCC	na			14491	-0.313	-0.0421	Yes
95	MUTYH	na			14539	-0.319	-0.0250	Yes
96	RPA3	na			14591	-0.326	-0.0078	Yes
97	POLD1	na			14892	-0.363	-0.0023	Yes
98	ALKBH2	na			15006	-0.378	0.0147	Yes
99	NTHL1	na			15259	-0.417	0.0263	Yes
100	POLR2I	na			15287	-0.421	0.0508	Yes
101	H2AFX	na			15352	-0.433	0.0739	Yes
102	CCNO	na			15882	-0.536	0.0772	Yes
103	MGMT	na			15883	-0.536	0.1104	Yes

Fig 2: REACTOME_DNA_REPAIR   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_DNA_REPAIR: Random ES distribution   
Gene set null distribution of ES for REACTOME_DNA_REPAIR