Details for gene set REACTOME_SIGNALLING_TO_RAS[GSEA]

Table: GSEA Results Summary

Dataset	normalized_counts_per_kilobase_for_GSEA_2.class_2.cls #AHRR-overexpressed_versus_Control
Phenotype	class_2.cls#AHRR-overexpressed_versus_Control
Upregulated in class	AHRR-overexpressed
GeneSet	REACTOME_SIGNALLING_TO_RAS
Enrichment Score (ES)	0.503277
Normalized Enrichment Score (NES)	1.7332851
Nominal p-value	0.0
FDR q-value	0.2771402
FWER p-Value	0.383

Fig 1: Enrichment plot: REACTOME_SIGNALLING_TO_RAS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NTRK1	na			131	2.985	0.2898	Yes
2	SHC3	na			246	2.209	0.5033	Yes
3	MAP2K1	na			1559	0.713	0.5006	No
4	RALA	na			4176	0.227	0.3764	No
5	MAPK1	na			4266	0.219	0.3932	No
6	RALB	na			4929	0.170	0.3729	No
7	GRB2	na			4985	0.166	0.3864	No
8	SOS1	na			5811	0.122	0.3523	No
9	YWHAB	na			6221	0.102	0.3395	No
10	MAPK14	na			6344	0.097	0.3423	No
11	MAP2K2	na			6878	0.073	0.3197	No
12	SHC1	na			7644	0.042	0.2809	No
13	RALGDS	na			7841	0.035	0.2734	No
14	RAF1	na			8761	0.000	0.2218	No
15	KRAS	na			9191	-0.016	0.1993	No
16	MAPK3	na			9820	-0.041	0.1681	No
17	NRAS	na			9998	-0.048	0.1630	No
18	HRAS	na			11793	-0.124	0.0746	No
19	MAPKAPK2	na			12125	-0.140	0.0699	No
20	MAPK11	na			12162	-0.142	0.0820	No
21	CDK1	na			13099	-0.196	0.0490	No
22	MAPK13	na			15066	-0.387	-0.0228	No
23	SHC2	na			15132	-0.397	0.0130	No
24	MAPK12	na			15148	-0.400	0.0520	No
25	SRC	na			15318	-0.427	0.0850	No
26	MAPKAPK3	na			16017	-0.568	0.1024	No

Fig 2: REACTOME_SIGNALLING_TO_RAS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_SIGNALLING_TO_RAS: Random ES distribution   
Gene set null distribution of ES for REACTOME_SIGNALLING_TO_RAS