Details for gene set REACTOME_CHOLESTEROL_BIOSYNTHESIS[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls #ClusterKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls#ClusterKO_versus_Cyp2c44KO
Upregulated in class	Cyp2c44KO
GeneSet	REACTOME_CHOLESTEROL_BIOSYNTHESIS
Enrichment Score (ES)	-0.57745206
Normalized Enrichment Score (NES)	-0.8935497
Nominal p-value	0.6782787
FDR q-value	0.86186504
FWER p-Value	0.999

Fig 1: Enrichment plot: REACTOME_CHOLESTEROL_BIOSYNTHESIS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Srebf1	na	1890	0.906	0.0811	No
2	Lbr	na	5761	0.479	0.0729	No
3	Plpp6	na	6454	0.439	0.1161	No
4	Dhcr24	na	9287	0.304	0.1044	No
5	Mvk	na	12110	0.190	0.0783	No
6	Srebf2	na	13341	0.142	0.0744	No
7	Arv1	na	16450	0.034	0.0236	No
8	Ggps1	na	16993	0.022	0.0167	No
9	Hmgcr	na	17186	0.018	0.0157	No
10	Idi2	na	18657	0.004	-0.0100	No
11	Idi2l	na	42940	0.000	-0.4409	No
12	Sqle	na	46540	-0.010	-0.5035	No
13	Acat2	na	47787	-0.037	-0.5209	No
14	Idi1	na	49157	-0.088	-0.5341	No
15	Cyp51	na	51601	-0.207	-0.5513	Yes
16	Msmo1	na	52061	-0.229	-0.5304	Yes
17	Hmgcs1	na	52135	-0.233	-0.5022	Yes
18	Fdft1	na	52713	-0.271	-0.4783	Yes
19	Sc5d	na	53324	-0.316	-0.4491	Yes
20	Lss	na	53400	-0.322	-0.4097	Yes
21	Mvd	na	53571	-0.335	-0.3704	Yes
22	Dhcr7	na	53657	-0.341	-0.3287	Yes
23	Hsd17b7	na	53950	-0.366	-0.2876	Yes
24	Ebp	na	54616	-0.434	-0.2445	Yes
25	Tm7sf2	na	54978	-0.483	-0.1898	Yes
26	Fdps	na	55154	-0.512	-0.1281	Yes
27	Nsdhl	na	55220	-0.524	-0.0630	Yes
28	Pmvk	na	55746	-0.660	0.0112	Yes

Fig 2: REACTOME_CHOLESTEROL_BIOSYNTHESIS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_CHOLESTEROL_BIOSYNTHESIS: Random ES distribution   
Gene set null distribution of ES for REACTOME_CHOLESTEROL_BIOSYNTHESIS