Details for gene set REACTOME_COLLAGEN_DEGRADATION[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls #ClusterKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls#ClusterKO_versus_Cyp2c44KO
Upregulated in class	ClusterKO
GeneSet	REACTOME_COLLAGEN_DEGRADATION
Enrichment Score (ES)	0.8200652
Normalized Enrichment Score (NES)	1.5118973
Nominal p-value	0.0
FDR q-value	0.10240979
FWER p-Value	0.257

Fig 1: Enrichment plot: REACTOME_COLLAGEN_DEGRADATION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Col6a3	na	43	2.215	0.0532	Yes
2	Col5a2	na	51	2.188	0.1063	Yes
3	Col3a1	na	89	2.027	0.1550	Yes
4	Col1a2	na	94	2.011	0.2039	Yes
5	Col1a1	na	138	1.868	0.2486	Yes
6	Mmp15	na	172	1.809	0.2920	Yes
7	Col4a1	na	215	1.736	0.3335	Yes
8	Col6a2	na	305	1.618	0.3713	Yes
9	Mmp12	na	351	1.580	0.4090	Yes
10	Mmp13	na	366	1.563	0.4468	Yes
11	Mmp2	na	390	1.536	0.4838	Yes
12	Col4a6	na	450	1.481	0.5188	Yes
13	Col4a5	na	476	1.461	0.5539	Yes
14	Col6a1	na	551	1.412	0.5870	Yes
15	Col15a1	na	647	1.355	0.6183	Yes
16	Col4a2	na	673	1.340	0.6505	Yes
17	Ctsk	na	801	1.271	0.6792	Yes
18	Col5a1	na	807	1.264	0.7098	Yes
19	Col11a1	na	1918	0.901	0.7121	Yes
20	Mmp14	na	1929	0.899	0.7338	Yes
21	Mmp8	na	2536	0.781	0.7420	Yes
22	Ctsb	na	2805	0.738	0.7552	Yes
23	Ctsd	na	3044	0.709	0.7683	Yes
24	Mmp9	na	3603	0.646	0.7741	Yes
25	Ctsl	na	4192	0.593	0.7781	Yes
26	Col8a1	na	4239	0.589	0.7916	Yes
27	Col6a6	na	4528	0.567	0.8003	Yes
28	Col12a1	na	4732	0.552	0.8101	Yes
29	Col6a5	na	4912	0.539	0.8201	Yes
30	Prss2	na	8226	0.353	0.7698	No
31	Try4	na	8242	0.353	0.7782	No
32	Try5	na	8807	0.326	0.7761	No
33	Tmprss6	na	12469	0.177	0.7154	No
34	Mmp11	na	12828	0.161	0.7129	No
35	Col18a1	na	15330	0.069	0.6702	No
36	Phykpl	na	15631	0.059	0.6663	No
37	Col25a1	na	15687	0.057	0.6668	No
38	Try10	na	16614	0.030	0.6510	No
39	Col8a2	na	17629	0.013	0.6334	No
40	Mmp10	na	18319	0.006	0.6213	No
41	Mmp20	na	18818	0.003	0.6125	No
42	Prss1	na	24326	0.000	0.5147	No
43	Gm5771	na	26525	0.000	0.4757	No
44	Col26a1	na	28290	0.000	0.4444	No
45	Col19a1	na	29274	0.000	0.4269	No
46	Gm10334	na	31161	0.000	0.3934	No
47	Prss3	na	31578	0.000	0.3860	No
48	Mmp1a	na	45075	0.000	0.1464	No
49	Col2a1	na	45817	-0.003	0.1333	No
50	Col10a1	na	45969	-0.004	0.1308	No
51	Furin	na	47622	-0.032	0.1022	No
52	Col5a3	na	49509	-0.103	0.0712	No
53	Col13a1	na	54845	-0.465	-0.0122	No
54	Col11a2	na	55459	-0.579	-0.0090	No
55	Col7a1	na	56269	-1.037	0.0019	No

Fig 2: REACTOME_COLLAGEN_DEGRADATION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_COLLAGEN_DEGRADATION: Random ES distribution   
Gene set null distribution of ES for REACTOME_COLLAGEN_DEGRADATION