Details for gene set REACTOME_ENDOGENOUS_STEROLS[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls #ClusterKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls#ClusterKO_versus_Cyp2c44KO
Upregulated in class	Cyp2c44KO
GeneSet	REACTOME_ENDOGENOUS_STEROLS
Enrichment Score (ES)	-0.375641
Normalized Enrichment Score (NES)	-0.85564196
Nominal p-value	0.74007934
FDR q-value	0.8940619
FWER p-Value	1.0

Fig 1: Enrichment plot: REACTOME_ENDOGENOUS_STEROLS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Ptgis	na	3526	0.653	0.0039	No
2	Cyp1b1	na	4809	0.547	0.0367	No
3	Ncoa2	na	5638	0.486	0.0715	No
4	Cyp4v3	na	6106	0.459	0.1098	No
5	Arnt2	na	6375	0.443	0.1502	No
6	Ahrr	na	6994	0.411	0.1810	No
7	Cyp11a1	na	7278	0.398	0.2165	No
8	Ncoa1	na	8931	0.321	0.2198	No
9	Rxra	na	9160	0.309	0.2473	No
10	Cyp11b1	na	9940	0.275	0.2615	No
11	Cyp21a1	na	10896	0.235	0.2685	No
12	Ahr	na	11541	0.211	0.2785	No
13	Arnt	na	12936	0.158	0.2698	No
14	Fdx1	na	14921	0.083	0.2430	No
15	Cyp11b2	na	18408	0.005	0.1817	No
16	Cyp19a1	na	35368	0.000	-0.1192	No
17	Cyp7b1	na	46598	-0.011	-0.3174	No
18	Cyp39a1	na	49016	-0.081	-0.3520	No
19	Fdxr	na	50351	-0.140	-0.3614	Yes
20	Pomc	na	50398	-0.141	-0.3479	Yes
21	Nr1h4	na	51483	-0.200	-0.3467	Yes
22	Cyp51	na	51601	-0.207	-0.3277	Yes
23	Cyp7a1	na	53420	-0.324	-0.3271	Yes
24	Fdx2	na	53718	-0.346	-0.2971	Yes
25	Cyp27a1	na	55760	-0.667	-0.2655	Yes
26	Cyp46a1	na	56257	-1.017	-0.1708	Yes
27	Cyp8b1	na	56365	-1.699	0.0002	Yes

Fig 2: REACTOME_ENDOGENOUS_STEROLS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_ENDOGENOUS_STEROLS: Random ES distribution   
Gene set null distribution of ES for REACTOME_ENDOGENOUS_STEROLS