| Dataset | RPKM_matrix___ClusterKO_vs_Cyp2c44KO.RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls #ClusterKO_versus_Cyp2c44KO |
| Phenotype | RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls#ClusterKO_versus_Cyp2c44KO |
| Upregulated in class | ClusterKO |
| GeneSet | REACTOME_KERATINIZATION |
| Enrichment Score (ES) | 0.72661245 |
| Normalized Enrichment Score (NES) | 1.5293063 |
| Nominal p-value | 0.0019230769 |
| FDR q-value | 0.10277351 |
| FWER p-Value | 0.189 |

| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | Ppl | na | 86 | 2.028 | 0.1089 | Yes |
| 2 | Krt19 | na | 261 | 1.670 | 0.1967 | Yes |
| 3 | Krt7 | na | 263 | 1.666 | 0.2874 | Yes |
| 4 | Krt8 | na | 486 | 1.456 | 0.3628 | Yes |
| 5 | Krt18 | na | 1019 | 1.162 | 0.4166 | Yes |
| 6 | Kazn | na | 2299 | 0.823 | 0.4386 | Yes |
| 7 | Dsg2 | na | 2803 | 0.738 | 0.4699 | Yes |
| 8 | Jup | na | 3249 | 0.683 | 0.4992 | Yes |
| 9 | Dsc2 | na | 3254 | 0.683 | 0.5363 | Yes |
| 10 | Tgm1 | na | 3382 | 0.667 | 0.5703 | Yes |
| 11 | Pkp1 | na | 3696 | 0.638 | 0.5995 | Yes |
| 12 | Evpl | na | 3969 | 0.614 | 0.6281 | Yes |
| 13 | Dsp | na | 3989 | 0.612 | 0.6610 | Yes |
| 14 | Pkp4 | na | 5380 | 0.502 | 0.6637 | Yes |
| 15 | Krt83 | na | 5475 | 0.496 | 0.6890 | Yes |
| 16 | Perp | na | 6084 | 0.460 | 0.7032 | Yes |
| 17 | Krt80 | na | 7184 | 0.402 | 0.7055 | Yes |
| 18 | Dsc3 | na | 7825 | 0.373 | 0.7145 | Yes |
| 19 | Cela2a | na | 8337 | 0.348 | 0.7243 | Yes |
| 20 | Spink5 | na | 9177 | 0.309 | 0.7262 | Yes |
| 21 | Pkp3 | na | 9993 | 0.274 | 0.7266 | Yes |
| 22 | Krt20 | na | 12412 | 0.179 | 0.6933 | No |
| 23 | Krt10 | na | 13033 | 0.153 | 0.6907 | No |
| 24 | Krt4 | na | 13988 | 0.117 | 0.6801 | No |
| 25 | Krt17 | na | 13992 | 0.117 | 0.6864 | No |
| 26 | Pkp2 | na | 14288 | 0.106 | 0.6869 | No |
| 27 | Krt23 | na | 15856 | 0.052 | 0.6618 | No |
| 28 | Krt16 | na | 16476 | 0.033 | 0.6526 | No |
| 29 | Dsg1a | na | 16567 | 0.031 | 0.6527 | No |
| 30 | Lipn | na | 16601 | 0.030 | 0.6538 | No |
| 31 | Cdsn | na | 17404 | 0.016 | 0.6404 | No |
| 32 | Krt5 | na | 17748 | 0.011 | 0.6349 | No |
| 33 | Dsc1 | na | 18238 | 0.007 | 0.6266 | No |
| 34 | Krt86 | na | 18422 | 0.005 | 0.6236 | No |
| 35 | Rptn | na | 18484 | 0.005 | 0.6228 | No |
| 36 | Krt6b | na | 18854 | 0.003 | 0.6163 | No |
| 37 | Klk14 | na | 18915 | 0.002 | 0.6154 | No |
| 38 | Klk13 | na | 19035 | 0.002 | 0.6134 | No |
| 39 | Krt24 | na | 19044 | 0.002 | 0.6133 | No |
| 40 | Dsg3 | na | 19096 | 0.001 | 0.6125 | No |
| 41 | 2310061N02Rik | na | 19318 | 0.000 | 0.6085 | No |
| 42 | Krt34 | na | 19658 | 0.000 | 0.6025 | No |
| 43 | Krtap29-1 | na | 20085 | 0.000 | 0.5949 | No |
| 44 | Gm7138 | na | 20132 | 0.000 | 0.5941 | No |
| 45 | Gm3238 | na | 20557 | 0.000 | 0.5866 | No |
| 46 | Krtap16-1 | na | 20583 | 0.000 | 0.5861 | No |
| 47 | Krtap19-4 | na | 20949 | 0.000 | 0.5796 | No |
| 48 | Krtap4-9 | na | 21342 | 0.000 | 0.5727 | No |
| 49 | Krt1 | na | 21431 | 0.000 | 0.5711 | No |
| 50 | Krtap5-4 | na | 21638 | 0.000 | 0.5674 | No |
| 51 | Lipk | na | 21906 | 0.000 | 0.5627 | No |
| 52 | Krt74 | na | 21915 | 0.000 | 0.5625 | No |
| 53 | Gm9789 | na | 21995 | 0.000 | 0.5611 | No |
| 54 | Gm40460 | na | 22437 | 0.000 | 0.5533 | No |
| 55 | Krtap31-2 | na | 22680 | 0.000 | 0.5490 | No |
| 56 | Krt2 | na | 22754 | 0.000 | 0.5477 | No |
| 57 | Krt14 | na | 22863 | 0.000 | 0.5458 | No |
| 58 | Krtap4-13 | na | 23112 | 0.000 | 0.5413 | No |
| 59 | Krtap10-10 | na | 23200 | 0.000 | 0.5398 | No |
| 60 | Gm7579 | na | 23258 | 0.000 | 0.5388 | No |
| 61 | Krt33a | na | 23266 | 0.000 | 0.5387 | No |
| 62 | Krtap2-4 | na | 23719 | 0.000 | 0.5306 | No |
| 63 | Krt76 | na | 24052 | 0.000 | 0.5247 | No |
| 64 | Gm10100 | na | 24313 | 0.000 | 0.5201 | No |
| 65 | 1110025L11Rik | na | 24427 | 0.000 | 0.5181 | No |
| 66 | Gm19402 | na | 25061 | 0.000 | 0.5068 | No |
| 67 | Gm7735 | na | 25476 | 0.000 | 0.4994 | No |
| 68 | Gm45337 | na | 25594 | 0.000 | 0.4974 | No |
| 69 | Krtap6-5 | na | 25685 | 0.000 | 0.4958 | No |
| 70 | Krt73 | na | 25987 | 0.000 | 0.4904 | No |
| 71 | Krt36 | na | 26471 | 0.000 | 0.4818 | No |
| 72 | Gm4553 | na | 27049 | 0.000 | 0.4715 | No |
| 73 | Krtap11-1 | na | 27299 | 0.000 | 0.4671 | No |
| 74 | Gm11559 | na | 27382 | 0.000 | 0.4657 | No |
| 75 | Krtap6-1 | na | 27472 | 0.000 | 0.4641 | No |
| 76 | Gm4559 | na | 27530 | 0.000 | 0.4631 | No |
| 77 | Gm9736 | na | 27535 | 0.000 | 0.4630 | No |
| 78 | Krt26 | na | 27862 | 0.000 | 0.4572 | No |
| 79 | Gm11565 | na | 28267 | 0.000 | 0.4500 | No |
| 80 | Gm11937 | na | 28722 | 0.000 | 0.4419 | No |
| 81 | Krtap19-3 | na | 28865 | 0.000 | 0.4394 | No |
| 82 | Krtap4-8 | na | 28896 | 0.000 | 0.4389 | No |
| 83 | Krt9 | na | 29851 | 0.000 | 0.4219 | No |
| 84 | 2310034C09Rik | na | 30001 | 0.000 | 0.4192 | No |
| 85 | Krtap5-2 | na | 30263 | 0.000 | 0.4146 | No |
| 86 | Krt27 | na | 30363 | 0.000 | 0.4128 | No |
| 87 | Gm29735 | na | 30491 | 0.000 | 0.4106 | No |
| 88 | Krtap3-2 | na | 30708 | 0.000 | 0.4067 | No |
| 89 | Stfa3 | na | 30862 | 0.000 | 0.4040 | No |
| 90 | Krtap8-1 | na | 31134 | 0.000 | 0.3992 | No |
| 91 | Gm11562 | na | 31420 | 0.000 | 0.3941 | No |
| 92 | Krtap4-16 | na | 31779 | 0.000 | 0.3877 | No |
| 93 | 2310057N15Rik | na | 31965 | 0.000 | 0.3845 | No |
| 94 | Krt13 | na | 32749 | 0.000 | 0.3705 | No |
| 95 | Krt6a | na | 32758 | 0.000 | 0.3704 | No |
| 96 | Gm11938 | na | 33145 | 0.000 | 0.3635 | No |
| 97 | Krtap20-2 | na | 33947 | 0.000 | 0.3493 | No |
| 98 | Krtap3-1 | na | 34100 | 0.000 | 0.3466 | No |
| 99 | Gm19668 | na | 34162 | 0.000 | 0.3455 | No |
| 100 | Gm9508 | na | 34362 | 0.000 | 0.3419 | No |
| 101 | Gm11569 | na | 34393 | 0.000 | 0.3414 | No |
| 102 | Gm11568 | na | 34583 | 0.000 | 0.3380 | No |
| 103 | Krtap5-1 | na | 34757 | 0.000 | 0.3350 | No |
| 104 | Gm11596 | na | 35459 | 0.000 | 0.3225 | No |
| 105 | Gm3250 | na | 35465 | 0.000 | 0.3224 | No |
| 106 | Krtap13 | na | 35668 | 0.000 | 0.3188 | No |
| 107 | Gm10228 | na | 35670 | 0.000 | 0.3188 | No |
| 108 | Gm10229 | na | 35776 | 0.000 | 0.3169 | No |
| 109 | Gm39115 | na | 35914 | 0.000 | 0.3145 | No |
| 110 | Krtap10-4 | na | 36048 | 0.000 | 0.3121 | No |
| 111 | Gm9507 | na | 36100 | 0.000 | 0.3112 | No |
| 112 | Gm10272 | na | 36150 | 0.000 | 0.3103 | No |
| 113 | Krt72 | na | 36308 | 0.000 | 0.3075 | No |
| 114 | Krt75 | na | 36385 | 0.000 | 0.3062 | No |
| 115 | Krt15 | na | 36504 | 0.000 | 0.3041 | No |
| 116 | Krtap31-1 | na | 36601 | 0.000 | 0.3024 | No |
| 117 | Krt12 | na | 36655 | 0.000 | 0.3014 | No |
| 118 | Krtap24-1 | na | 36805 | 0.000 | 0.2988 | No |
| 119 | Krtap16-3 | na | 36878 | 0.000 | 0.2975 | No |
| 120 | Gm11595 | na | 36908 | 0.000 | 0.2970 | No |
| 121 | 1110057P08Rik | na | 37059 | 0.000 | 0.2943 | No |
| 122 | Gm6358 | na | 37473 | 0.000 | 0.2870 | No |
| 123 | Gm11564 | na | 37494 | 0.000 | 0.2866 | No |
| 124 | Krt84 | na | 37810 | 0.000 | 0.2810 | No |
| 125 | Krtap6-3 | na | 38110 | 0.000 | 0.2757 | No |
| 126 | Gm7137 | na | 38306 | 0.000 | 0.2722 | No |
| 127 | Lipm | na | 38407 | 0.000 | 0.2704 | No |
| 128 | Gm5478 | na | 38455 | 0.000 | 0.2696 | No |
| 129 | 2300003K06Rik | na | 38889 | 0.000 | 0.2619 | No |
| 130 | Krt25 | na | 38954 | 0.000 | 0.2608 | No |
| 131 | Krt40 | na | 39196 | 0.000 | 0.2565 | No |
| 132 | Krt82 | na | 39954 | 0.000 | 0.2430 | No |
| 133 | Krt35 | na | 39981 | 0.000 | 0.2425 | No |
| 134 | Krt32 | na | 40062 | 0.000 | 0.2411 | No |
| 135 | Gm10061 | na | 40223 | 0.000 | 0.2383 | No |
| 136 | Gm10318 | na | 40481 | 0.000 | 0.2337 | No |
| 137 | Krt33b | na | 40525 | 0.000 | 0.2329 | No |
| 138 | Krtap4-6 | na | 40622 | 0.000 | 0.2312 | No |
| 139 | Gm20741 | na | 40787 | 0.000 | 0.2283 | No |
| 140 | Gm18596 | na | 40832 | 0.000 | 0.2275 | No |
| 141 | Gm10142 | na | 41196 | 0.000 | 0.2211 | No |
| 142 | Krtap12-1 | na | 41242 | 0.000 | 0.2203 | No |
| 143 | Krtap5-5 | na | 41335 | 0.000 | 0.2186 | No |
| 144 | Klk12 | na | 41551 | 0.000 | 0.2148 | No |
| 145 | Gm10153 | na | 41711 | 0.000 | 0.2120 | No |
| 146 | Krtap19-2 | na | 41807 | 0.000 | 0.2103 | No |
| 147 | Gm10024 | na | 41808 | 0.000 | 0.2103 | No |
| 148 | Gm3233 | na | 41846 | 0.000 | 0.2096 | No |
| 149 | Krt31 | na | 42006 | 0.000 | 0.2068 | No |
| 150 | Gm9639 | na | 42431 | 0.000 | 0.1993 | No |
| 151 | Dsg4 | na | 42533 | 0.000 | 0.1975 | No |
| 152 | Krtap19-5 | na | 43100 | 0.000 | 0.1874 | No |
| 153 | Krtap19-1 | na | 43381 | 0.000 | 0.1824 | No |
| 154 | Klk5 | na | 43789 | 0.000 | 0.1752 | No |
| 155 | Gm5965 | na | 43868 | 0.000 | 0.1738 | No |
| 156 | Gm5414 | na | 43964 | 0.000 | 0.1721 | No |
| 157 | Krtap3-3 | na | 43992 | 0.000 | 0.1716 | No |
| 158 | Gm3285 | na | 44678 | 0.000 | 0.1594 | No |
| 159 | Gm11554 | na | 45206 | 0.000 | 0.1500 | No |
| 160 | Gm45618 | na | 45209 | 0.000 | 0.1500 | No |
| 161 | Krt81 | na | 45234 | 0.000 | 0.1496 | No |
| 162 | Spink6 | na | 45356 | 0.000 | 0.1474 | No |
| 163 | Krt39 | na | 45655 | -0.002 | 0.1422 | No |
| 164 | Krtap9-1 | na | 45733 | -0.003 | 0.1410 | No |
| 165 | Tchh | na | 46554 | -0.010 | 0.1270 | No |
| 166 | Krt77 | na | 46650 | -0.012 | 0.1259 | No |
| 167 | Krt71 | na | 46999 | -0.018 | 0.1207 | No |
| 168 | Krt79 | na | 47744 | -0.035 | 0.1094 | No |
| 169 | Krt78 | na | 48454 | -0.059 | 0.1000 | No |
| 170 | Klk8 | na | 49241 | -0.092 | 0.0910 | No |
| 171 | Gm11567 | na | 50928 | -0.169 | 0.0702 | No |
| 172 | Krt28 | na | 55038 | -0.491 | 0.0238 | No |

