Details for gene set REACTOME_PYRUVATE_METABOLISM[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls #ClusterKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls#ClusterKO_versus_Cyp2c44KO
Upregulated in class	Cyp2c44KO
GeneSet	REACTOME_PYRUVATE_METABOLISM
Enrichment Score (ES)	-0.43161583
Normalized Enrichment Score (NES)	-0.9941342
Nominal p-value	0.41619587
FDR q-value	1.0
FWER p-Value	0.995

Fig 1: Enrichment plot: REACTOME_PYRUVATE_METABOLISM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Pdk3	na	345	1.585	0.1628	No
2	Pdp1	na	1332	1.052	0.2574	No
3	Vdac1	na	8295	0.350	0.1712	No
4	Rxra	na	9160	0.309	0.1889	No
5	Ldha	na	11054	0.229	0.1797	No
6	Dld	na	11571	0.209	0.1928	No
7	Pdpr	na	12632	0.169	0.1921	No
8	Pdha1	na	12951	0.157	0.2032	No
9	Pdhb	na	13196	0.147	0.2146	No
10	Pdhx	na	13717	0.129	0.2191	No
11	Ldhc	na	19012	0.002	0.1253	No
12	Pdha2	na	29434	0.000	-0.0596	No
13	Hagh	na	47830	-0.038	-0.3820	No
14	Pdk2	na	50629	-0.154	-0.4152	Yes
15	Gstz1	na	51267	-0.188	-0.4065	Yes
16	Ppard	na	51345	-0.192	-0.3874	Yes
17	Dlat	na	51875	-0.222	-0.3732	Yes
18	Glo1	na	53211	-0.306	-0.3643	Yes
19	Ldhb	na	54163	-0.385	-0.3401	Yes
20	Pdk4	na	55043	-0.492	-0.3033	Yes
21	Pdk1	na	55454	-0.578	-0.2490	Yes
22	Pdp2	na	55864	-0.706	-0.1810	Yes
23	Ldhal6b	na	55969	-0.760	-0.1019	Yes
24	Me1	na	56262	-1.024	0.0020	Yes

Fig 2: REACTOME_PYRUVATE_METABOLISM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_PYRUVATE_METABOLISM: Random ES distribution   
Gene set null distribution of ES for REACTOME_PYRUVATE_METABOLISM