Details for gene set WP_FOCAL_ADHESION[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls #ClusterKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls#ClusterKO_versus_Cyp2c44KO
Upregulated in class	ClusterKO
GeneSet	WP_FOCAL_ADHESION
Enrichment Score (ES)	0.7360021
Normalized Enrichment Score (NES)	1.4165789
Nominal p-value	0.001996008
FDR q-value	0.06926594
FWER p-Value	0.355

Fig 1: Enrichment plot: WP_FOCAL_ADHESION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Itgax	na	27	2.329	0.0172	Yes
2	Col5a2	na	51	2.188	0.0335	Yes
3	Col3a1	na	89	2.027	0.0482	Yes
4	Col1a2	na	94	2.011	0.0634	Yes
5	Pdgfrb	na	120	1.934	0.0777	Yes
6	Pdgfb	na	130	1.893	0.0919	Yes
7	Col1a1	na	138	1.868	0.1060	Yes
8	Cav2	na	155	1.831	0.1196	Yes
9	Col4a1	na	215	1.736	0.1318	Yes
10	Fgr	na	219	1.726	0.1449	Yes
11	Itgb4	na	236	1.711	0.1576	Yes
12	Src	na	286	1.640	0.1692	Yes
13	Col6a2	na	305	1.618	0.1812	Yes
14	Spp1	na	306	1.617	0.1935	Yes
15	Lama2	na	320	1.602	0.2054	Yes
16	Lama5	na	330	1.597	0.2174	Yes
17	Itgb2	na	397	1.529	0.2278	Yes
18	Col4a6	na	450	1.481	0.2382	Yes
19	Pdgfra	na	466	1.466	0.2491	Yes
20	Pik3r5	na	485	1.456	0.2598	Yes
21	Flna	na	516	1.438	0.2702	Yes
22	Col4a2	na	673	1.340	0.2776	Yes
23	Vav1	na	679	1.334	0.2877	Yes
24	Itgav	na	717	1.312	0.2970	Yes
25	Itgam	na	718	1.311	0.3070	Yes
26	Cav1	na	734	1.304	0.3166	Yes
27	Actn1	na	744	1.298	0.3263	Yes
28	Itga8	na	781	1.281	0.3354	Yes
29	Col5a1	na	807	1.264	0.3446	Yes
30	Akt3	na	817	1.258	0.3540	Yes
31	Pik3cg	na	855	1.239	0.3628	Yes
32	Vasp	na	893	1.222	0.3714	Yes
33	Actb	na	930	1.201	0.3799	Yes
34	Thbs2	na	932	1.200	0.3890	Yes
35	Pdgfa	na	933	1.198	0.3981	Yes
36	Pdgfd	na	946	1.194	0.4070	Yes
37	Lamc1	na	947	1.194	0.4161	Yes
38	Lamc2	na	973	1.183	0.4246	Yes
39	Mapk7	na	1010	1.164	0.4328	Yes
40	Hck	na	1130	1.123	0.4392	Yes
41	Itga4	na	1166	1.105	0.4470	Yes
42	Pak6	na	1168	1.105	0.4554	Yes
43	Pak1	na	1172	1.102	0.4637	Yes
44	Vcl	na	1185	1.098	0.4719	Yes
45	Thbs4	na	1228	1.088	0.4794	Yes
46	Itga9	na	1242	1.083	0.4874	Yes
47	Itgb8	na	1259	1.077	0.4953	Yes
48	Bcl2	na	1285	1.071	0.5030	Yes
49	Itga2	na	1286	1.071	0.5111	Yes
50	Tnc	na	1292	1.067	0.5191	Yes
51	Pak3	na	1368	1.041	0.5257	Yes
52	Thbs1	na	1376	1.040	0.5335	Yes
53	Itga6	na	1415	1.028	0.5407	Yes
54	Pdgfc	na	1461	1.013	0.5476	Yes
55	Rac2	na	1555	0.991	0.5534	Yes
56	Rap1b	na	1662	0.958	0.5588	Yes
57	Itgb5	na	1724	0.944	0.5649	Yes
58	Lamb1	na	1799	0.928	0.5707	Yes
59	Itgal	na	1838	0.918	0.5770	Yes
60	Cdc42	na	1888	0.906	0.5830	Yes
61	Erbb2	na	1909	0.904	0.5895	Yes
62	Col11a1	na	1918	0.901	0.5962	Yes
63	Pik3cd	na	2000	0.883	0.6015	Yes
64	Itgb6	na	2019	0.876	0.6078	Yes
65	Reln	na	2132	0.855	0.6123	Yes
66	Birc3	na	2142	0.852	0.6187	Yes
67	Mapk6	na	2183	0.844	0.6244	Yes
68	Hgf	na	2361	0.811	0.6274	Yes
69	Pak2	na	2368	0.810	0.6334	Yes
70	Styk1	na	2486	0.791	0.6374	Yes
71	Akt1	na	2566	0.775	0.6419	Yes
72	Itga3	na	2631	0.765	0.6465	Yes
73	Rap1a	na	2766	0.744	0.6498	Yes
74	Rock2	na	2876	0.728	0.6534	Yes
75	Tnxb	na	2885	0.727	0.6588	Yes
76	Vegfc	na	3021	0.711	0.6618	Yes
77	Dock1	na	3080	0.704	0.6661	Yes
78	Itga5	na	3338	0.673	0.6666	Yes
79	Rhob	na	3508	0.654	0.6686	Yes
80	Actg1	na	3914	0.619	0.6661	Yes
81	Met	na	3990	0.612	0.6694	Yes
82	Itgb1	na	4038	0.607	0.6732	Yes
83	Pten	na	4212	0.590	0.6746	Yes
84	Crkl	na	4356	0.580	0.6765	Yes
85	Pik3cb	na	4728	0.552	0.6741	Yes
86	Vtn	na	4779	0.549	0.6774	Yes
87	Grb2	na	4783	0.548	0.6815	Yes
88	Parvb	na	4837	0.544	0.6847	Yes
89	Map2k3	na	4915	0.539	0.6874	Yes
90	Crk	na	4924	0.538	0.6914	Yes
91	Itgb7	na	4932	0.537	0.6953	Yes
92	Rhoa	na	4959	0.535	0.6989	Yes
93	Bad	na	4961	0.535	0.7030	Yes
94	Rock1	na	5099	0.525	0.7045	Yes
95	Itga11	na	5109	0.524	0.7084	Yes
96	Gsk3b	na	5233	0.515	0.7101	Yes
97	Ptk2	na	5236	0.515	0.7140	Yes
98	Pak4	na	5244	0.514	0.7177	Yes
99	Pip5k1c	na	5579	0.490	0.7155	Yes
100	Thbs3	na	5601	0.488	0.7189	Yes
101	Mapk1	na	5650	0.485	0.7217	Yes
102	Capn1	na	6019	0.463	0.7187	Yes
103	Rac1	na	6117	0.458	0.7204	Yes
104	Birc2	na	6158	0.456	0.7232	Yes
105	Lama4	na	6308	0.447	0.7239	Yes
106	Lamb2	na	6344	0.445	0.7267	Yes
107	Itgad	na	6602	0.431	0.7254	Yes
108	Map2k6	na	6948	0.413	0.7224	Yes
109	Zyx	na	7023	0.409	0.7242	Yes
110	Map2k1	na	7116	0.405	0.7256	Yes
111	Pik3r1	na	7254	0.399	0.7262	Yes
112	Raf1	na	7290	0.398	0.7286	Yes
113	Lamc3	na	7357	0.395	0.7305	Yes
114	Shc1	na	7378	0.394	0.7331	Yes
115	Selenop	na	7384	0.394	0.7360	Yes
116	Tnk1	na	7589	0.384	0.7353	No
117	Fn1	na	7934	0.367	0.7320	No
118	Ccnd2	na	8235	0.353	0.7293	No
119	Ccnd1	na	8289	0.351	0.7310	No
120	Mapk9	na	8443	0.343	0.7309	No
121	Igf1	na	8454	0.342	0.7333	No
122	Egfr	na	8660	0.333	0.7322	No
123	Rapgef1	na	8867	0.323	0.7310	No
124	Pdpk1	na	9161	0.309	0.7282	No
125	Elk1	na	9185	0.308	0.7301	No
126	Arhgap5	na	9380	0.301	0.7289	No
127	Pik3r2	na	9603	0.291	0.7272	No
128	Ilk	na	10134	0.268	0.7198	No
129	Mapk8	na	10431	0.255	0.7165	No
130	Diaph1	na	10746	0.242	0.7127	No
131	Pgf	na	10915	0.234	0.7115	No
132	Pik3ca	na	11645	0.207	0.7001	No
133	Braf	na	11910	0.196	0.6969	No
134	Map2k2	na	12044	0.192	0.6960	No
135	Itgae	na	12120	0.190	0.6961	No
136	Pik3r4	na	12131	0.189	0.6974	No
137	Lama1	na	12309	0.183	0.6956	No
138	Cav3	na	12316	0.183	0.6969	No
139	Pxn	na	12509	0.175	0.6948	No
140	Col4a4	na	13142	0.149	0.6847	No
141	Tln1	na	13576	0.132	0.6780	No
142	Akt2	na	13614	0.132	0.6783	No
143	Vegfb	na	14559	0.096	0.6623	No
144	Ptk6	na	14588	0.096	0.6625	No
145	Sos1	na	15662	0.058	0.6438	No
146	Chad	na	16098	0.044	0.6364	No
147	Fyn	na	16201	0.041	0.6349	No
148	Txk	na	16845	0.025	0.6237	No
149	Pelo	na	17281	0.017	0.6161	No
150	Lama3	na	17972	0.009	0.6039	No
151	Mylk2	na	18034	0.009	0.6028	No
152	Bcar1	na	18139	0.008	0.6010	No
153	Tnn	na	19138	0.001	0.5833	No
154	Ibsp	na	23488	0.000	0.5059	No
155	Shc3	na	45400	-0.001	0.1160	No
156	Myl6	na	45497	-0.001	0.1143	No
157	Col2a1	na	45817	-0.003	0.1086	No
158	Map2k5	na	47914	-0.040	0.0716	No
159	Itgb3	na	48205	-0.050	0.0668	No
160	Araf	na	49401	-0.098	0.0463	No
161	Col5a3	na	49509	-0.103	0.0452	No
162	Rac3	na	50165	-0.132	0.0346	No
163	Blk	na	50294	-0.137	0.0333	No
164	Ppp1r12a	na	50327	-0.138	0.0338	No
165	Itga7	na	50435	-0.143	0.0330	No
166	Tesk2	na	50561	-0.149	0.0319	No
167	Tnr	na	51689	-0.212	0.0134	No
168	Ccnd3	na	51911	-0.223	0.0112	No
169	Mylk	na	52272	-0.242	0.0066	No
170	Pak5	na	52630	-0.265	0.0023	No
171	Mapk12	na	53628	-0.339	-0.0129	No
172	Srms	na	54005	-0.372	-0.0167	No
173	Farp2	na	54567	-0.428	-0.0235	No
174	Flt1	na	54568	-0.428	-0.0202	No
175	Lamb3	na	54941	-0.477	-0.0232	No
176	Itga2b	na	55091	-0.502	-0.0220	No
177	Itga10	na	55312	-0.544	-0.0218	No
178	Vegfd	na	55444	-0.576	-0.0198	No
179	Col11a2	na	55459	-0.579	-0.0156	No
180	Tnk2	na	55486	-0.583	-0.0116	No
181	Jun	na	55488	-0.584	-0.0072	No
182	Vwf	na	55671	-0.633	-0.0056	No
183	Egf	na	55719	-0.651	-0.0015	No
184	Mapk4	na	56045	-0.819	-0.0011	No
185	Vegfa	na	56181	-0.917	0.0035	No

Fig 2: WP_FOCAL_ADHESION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_FOCAL_ADHESION: Random ES distribution   
Gene set null distribution of ES for WP_FOCAL_ADHESION