Details for gene set WP_TRYPTOPHAN_METABOLISM[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls #ClusterKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___ClusterKO_vs_Cyp2c44KO.cls#ClusterKO_versus_Cyp2c44KO
Upregulated in class	Cyp2c44KO
GeneSet	WP_TRYPTOPHAN_METABOLISM
Enrichment Score (ES)	-0.40175968
Normalized Enrichment Score (NES)	-0.95509547
Nominal p-value	0.5433884
FDR q-value	0.51775444
FWER p-Value	0.98

Fig 1: Enrichment plot: WP_TRYPTOPHAN_METABOLISM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Aldh1a2	na	1196	1.096	0.0473	No
2	Prmt1	na	2012	0.878	0.0878	No
3	Aoc1	na	3660	0.641	0.0986	No
4	Wars1	na	4453	0.573	0.1204	No
5	Cyp1b1	na	4809	0.547	0.1483	No
6	Cyp2j6	na	5114	0.524	0.1756	No
7	Cyp1a2	na	5764	0.479	0.1941	No
8	Acmsd	na	5775	0.478	0.2238	No
9	Cyp2f2	na	6312	0.447	0.2422	No
10	Ube3a	na	7597	0.384	0.2434	No
11	Dhcr24	na	9287	0.304	0.2325	No
12	Ubr5	na	10371	0.257	0.2293	No
13	Echs1	na	11102	0.228	0.2306	No
14	Mdm2	na	11704	0.205	0.2328	No
15	Ido1	na	12805	0.162	0.2234	No
16	Cyp4f14	na	13799	0.126	0.2137	No
17	Kynu	na	13902	0.121	0.2195	No
18	Ogdh	na	14907	0.084	0.2069	No
19	Ddc	na	15991	0.047	0.1906	No
20	Asmt	na	18916	0.002	0.1388	No
21	Aanat	na	18939	0.002	0.1386	No
22	Tph1	na	21947	0.000	0.0852	No
23	Cyp19a1	na	35368	0.000	-0.1530	No
24	Cyp7b1	na	46598	-0.011	-0.3516	No
25	Aadat	na	47572	-0.031	-0.3670	No
26	Tdo2	na	48271	-0.052	-0.3761	No
27	Cat	na	48618	-0.065	-0.3782	No
28	Rnf25	na	48671	-0.067	-0.3749	No
29	Maob	na	50025	-0.126	-0.3910	No
30	Inmt	na	50630	-0.154	-0.3922	Yes
31	Cyp1a1	na	51107	-0.178	-0.3895	Yes
32	Aldh2	na	51435	-0.197	-0.3829	Yes
33	Aldh1a1	na	51860	-0.221	-0.3767	Yes
34	Hsd17b10	na	52057	-0.229	-0.3658	Yes
35	Gcdh	na	52972	-0.288	-0.3640	Yes
36	Hadh	na	53083	-0.296	-0.3474	Yes
37	Aox1	na	53106	-0.298	-0.3292	Yes
38	Afmid	na	53488	-0.328	-0.3154	Yes
39	Cyp2e1	na	53717	-0.346	-0.2979	Yes
40	Aldh9a1	na	53902	-0.362	-0.2785	Yes
41	Haao	na	54559	-0.428	-0.2634	Yes
42	Acat1	na	55844	-0.700	-0.2425	Yes
43	Aldh3a2	na	56207	-0.940	-0.1901	Yes
44	Cyp2c55	na	56372	-3.088	0.0001	Yes

Fig 2: WP_TRYPTOPHAN_METABOLISM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_TRYPTOPHAN_METABOLISM: Random ES distribution   
Gene set null distribution of ES for WP_TRYPTOPHAN_METABOLISM