Details for gene set REACTOME_CHOLESTEROL_BIOSYNTHESIS[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___ClusterKO_vs_WT.RPKM_matrix___ClusterKO_vs_WT.cls #ClusterKO_versus_WT
Phenotype	RPKM_matrix___ClusterKO_vs_WT.cls#ClusterKO_versus_WT
Upregulated in class	WT
GeneSet	REACTOME_CHOLESTEROL_BIOSYNTHESIS
Enrichment Score (ES)	-0.8712849
Normalized Enrichment Score (NES)	-1.3656507
Nominal p-value	0.021484375
FDR q-value	0.40939233
FWER p-Value	0.846

Fig 1: Enrichment plot: REACTOME_CHOLESTEROL_BIOSYNTHESIS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Arv1	na	2960	0.847	-0.0197	No
2	Ggps1	na	4605	0.674	-0.0227	No
3	Lbr	na	6934	0.506	-0.0444	No
4	Srebf1	na	8031	0.441	-0.0467	No
5	Plpp6	na	9061	0.383	-0.0501	No
6	Idi2	na	20855	0.004	-0.2593	No
7	Idi2l	na	43134	0.000	-0.6546	No
8	Srebf2	na	51771	-0.111	-0.8036	No
9	Dhcr24	na	52293	-0.140	-0.8074	No
10	Hmgcr	na	55895	-0.547	-0.8501	Yes
11	Sc5d	na	56117	-0.682	-0.8275	Yes
12	Idi1	na	56164	-0.723	-0.8003	Yes
13	Ebp	na	56204	-0.756	-0.7717	Yes
14	Acat2	na	56269	-0.884	-0.7385	Yes
15	Hsd17b7	na	56285	-0.938	-0.7024	Yes
16	Mvk	na	56287	-0.947	-0.6657	Yes
17	Sqle	na	56298	-0.989	-0.6275	Yes
18	Tm7sf2	na	56304	-1.008	-0.5885	Yes
19	Hmgcs1	na	56306	-1.018	-0.5491	Yes
20	Cyp51	na	56334	-1.221	-0.5022	Yes
21	Msmo1	na	56341	-1.284	-0.4525	Yes
22	Dhcr7	na	56348	-1.365	-0.3996	Yes
23	Mvd	na	56353	-1.438	-0.3439	Yes
24	Fdft1	na	56358	-1.524	-0.2849	Yes
25	Pmvk	na	56362	-1.649	-0.2210	Yes
26	Lss	na	56367	-1.723	-0.1542	Yes
27	Nsdhl	na	56370	-1.910	-0.0802	Yes
28	Fdps	na	56372	-2.069	0.0001	Yes

Fig 2: REACTOME_CHOLESTEROL_BIOSYNTHESIS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_CHOLESTEROL_BIOSYNTHESIS: Random ES distribution   
Gene set null distribution of ES for REACTOME_CHOLESTEROL_BIOSYNTHESIS