Details for gene set REACTOME_COLLAGEN_FORMATION[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___ClusterKO_vs_WT.RPKM_matrix___ClusterKO_vs_WT.cls #ClusterKO_versus_WT
Phenotype	RPKM_matrix___ClusterKO_vs_WT.cls#ClusterKO_versus_WT
Upregulated in class	ClusterKO
GeneSet	REACTOME_COLLAGEN_FORMATION
Enrichment Score (ES)	0.77160037
Normalized Enrichment Score (NES)	1.4858402
Nominal p-value	0.0
FDR q-value	0.4755355
FWER p-Value	0.347

Fig 1: Enrichment plot: REACTOME_COLLAGEN_FORMATION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Loxl2	na	35	2.443	0.0407	Yes
2	Col5a2	na	39	2.372	0.0808	Yes
3	Col6a3	na	60	2.264	0.1188	Yes
4	Col1a2	na	157	1.971	0.1504	Yes
5	Col3a1	na	165	1.951	0.1833	Yes
6	Lox	na	208	1.883	0.2144	Yes
7	Ctss	na	304	1.761	0.2426	Yes
8	Col4a1	na	348	1.711	0.2708	Yes
9	Col1a1	na	355	1.707	0.2995	Yes
10	Adamts2	na	362	1.701	0.3282	Yes
11	Loxl1	na	423	1.647	0.3550	Yes
12	Plod2	na	434	1.637	0.3826	Yes
13	Mmp13	na	530	1.567	0.4074	Yes
14	Col5a1	na	566	1.533	0.4327	Yes
15	Col14a1	na	620	1.495	0.4571	Yes
16	P3h3	na	649	1.477	0.4816	Yes
17	Col16a1	na	787	1.409	0.5030	Yes
18	Col4a2	na	788	1.409	0.5269	Yes
19	Serpinh1	na	1023	1.296	0.5446	Yes
20	Pcolce	na	1039	1.290	0.5662	Yes
21	Col4a6	na	1043	1.288	0.5880	Yes
22	Col28a1	na	1056	1.284	0.6095	Yes
23	Col6a2	na	1152	1.245	0.6289	Yes
24	Loxl3	na	1209	1.226	0.6486	Yes
25	Crtap	na	1231	1.216	0.6688	Yes
26	Col4a5	na	1291	1.193	0.6880	Yes
27	Col6a1	na	1299	1.190	0.7080	Yes
28	P3h2	na	1682	1.073	0.7194	Yes
29	Pxdn	na	2327	0.946	0.7239	Yes
30	Ctsb	na	2678	0.889	0.7328	Yes
31	Pcolce2	na	3173	0.822	0.7379	Yes
32	Adamts14	na	3308	0.806	0.7492	Yes
33	Mmp9	na	3473	0.787	0.7596	Yes
34	Colgalt1	na	3540	0.779	0.7716	Yes
35	Col6a5	na	4528	0.681	0.7656	No
36	Ctsl	na	5276	0.622	0.7629	No
37	Col23a1	na	5388	0.613	0.7713	No
38	Col6a6	na	7650	0.463	0.7389	No
39	P3h1	na	8162	0.434	0.7372	No
40	Col12a1	na	8950	0.389	0.7298	No
41	Col25a1	na	9895	0.339	0.7188	No
42	Col8a1	na	10662	0.299	0.7102	No
43	Loxl4	na	10922	0.285	0.7105	No
44	Col15a1	na	11005	0.282	0.7138	No
45	P4ha1	na	11736	0.245	0.7050	No
46	Col17a1	na	11854	0.239	0.7069	No
47	Col5a3	na	12373	0.217	0.7014	No
48	Plod3	na	12796	0.197	0.6972	No
49	Adamts3	na	12824	0.196	0.7001	No
50	Col18a1	na	13609	0.163	0.6889	No
51	Col9a3	na	13719	0.158	0.6897	No
52	Colgalt2	na	14662	0.120	0.6750	No
53	Col13a1	na	14775	0.115	0.6749	No
54	Col4a4	na	16618	0.052	0.6431	No
55	Col11a1	na	19523	0.011	0.5917	No
56	Mmp20	na	21100	0.003	0.5637	No
57	Col24a1	na	21683	0.001	0.5534	No
58	Col26a1	na	28988	0.000	0.4237	No
59	Col19a1	na	30003	0.000	0.4057	No
60	Col10a1	na	30180	0.000	0.4025	No
61	Col2a1	na	37874	0.000	0.2659	No
62	Col11a2	na	49106	-0.000	0.0664	No
63	Col22a1	na	49123	-0.001	0.0662	No
64	Tll2	na	49263	-0.005	0.0638	No
65	Tll1	na	50333	-0.042	0.0455	No
66	Col9a1	na	50378	-0.044	0.0455	No
67	P4ha3	na	51702	-0.107	0.0238	No
68	Plod1	na	52633	-0.161	0.0100	No
69	P4hb	na	52968	-0.182	0.0071	No
70	Bmp1	na	54240	-0.279	-0.0107	No
71	Col9a2	na	54252	-0.280	-0.0062	No
72	Col7a1	na	54469	-0.299	-0.0050	No
73	Col20a1	na	54885	-0.340	-0.0066	No
74	Ppib	na	55075	-0.364	-0.0038	No
75	Col27a1	na	55130	-0.374	0.0016	No
76	P4ha2	na	55870	-0.535	-0.0025	No
77	Col8a2	na	56112	-0.677	0.0047	No

Fig 2: REACTOME_COLLAGEN_FORMATION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_COLLAGEN_FORMATION: Random ES distribution   
Gene set null distribution of ES for REACTOME_COLLAGEN_FORMATION