Details for gene set WP_CHOLESTEROL_BIOSYNTHESIS[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___ClusterKO_vs_WT.RPKM_matrix___ClusterKO_vs_WT.cls #ClusterKO_versus_WT
Phenotype	RPKM_matrix___ClusterKO_vs_WT.cls#ClusterKO_versus_WT
Upregulated in class	WT
GeneSet	WP_CHOLESTEROL_BIOSYNTHESIS
Enrichment Score (ES)	-0.99169666
Normalized Enrichment Score (NES)	-1.2974671
Nominal p-value	0.002057613
FDR q-value	0.3022095
FWER p-Value	0.775

Fig 1: Enrichment plot: WP_CHOLESTEROL_BIOSYNTHESIS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Hmgcr	na	55895	-0.547	-0.9630	Yes
2	Sc5d	na	56117	-0.682	-0.9312	Yes
3	Idi1	na	56164	-0.723	-0.8941	Yes
4	Mvk	na	56287	-0.947	-0.8467	Yes
5	Sqle	na	56298	-0.989	-0.7951	Yes
6	Hmgcs1	na	56306	-1.018	-0.7419	Yes
7	Cyp51	na	56334	-1.221	-0.6784	Yes
8	Msmo1	na	56341	-1.284	-0.6112	Yes
9	Dhcr7	na	56348	-1.365	-0.5398	Yes
10	Mvd	na	56353	-1.438	-0.4646	Yes
11	Fdft1	na	56358	-1.524	-0.3848	Yes
12	Pmvk	na	56362	-1.649	-0.2985	Yes
13	Lss	na	56367	-1.723	-0.2083	Yes
14	Nsdhl	na	56370	-1.910	-0.1083	Yes
15	Fdps	na	56372	-2.069	0.0001	Yes

Fig 2: WP_CHOLESTEROL_BIOSYNTHESIS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_CHOLESTEROL_BIOSYNTHESIS: Random ES distribution   
Gene set null distribution of ES for WP_CHOLESTEROL_BIOSYNTHESIS