| Dataset | RPKM_matrix___ClusterKO_vs_WT.RPKM_matrix___ClusterKO_vs_WT.cls #ClusterKO_versus_WT |
| Phenotype | RPKM_matrix___ClusterKO_vs_WT.cls#ClusterKO_versus_WT |
| Upregulated in class | ClusterKO |
| GeneSet | WP_GPCRS_OTHER |
| Enrichment Score (ES) | 0.68286526 |
| Normalized Enrichment Score (NES) | 1.4101765 |
| Nominal p-value | 0.010121457 |
| FDR q-value | 0.083058424 |
| FWER p-Value | 0.423 |

| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | Adgrg1 | na | 806 | 1.401 | 0.0500 | Yes |
| 2 | Adgre5 | na | 906 | 1.350 | 0.1102 | Yes |
| 3 | Ccr7 | na | 1273 | 1.201 | 0.1588 | Yes |
| 4 | S1pr2 | na | 1412 | 1.159 | 0.2095 | Yes |
| 5 | Gpr34 | na | 1821 | 1.040 | 0.2500 | Yes |
| 6 | Ednra | na | 1950 | 1.016 | 0.2944 | Yes |
| 7 | Ackr1 | na | 2027 | 1.003 | 0.3390 | Yes |
| 8 | Gpr132 | na | 2287 | 0.954 | 0.3782 | Yes |
| 9 | Gpr84 | na | 2354 | 0.942 | 0.4203 | Yes |
| 10 | Adrb1 | na | 3152 | 0.824 | 0.4439 | Yes |
| 11 | Cysltr1 | na | 3380 | 0.797 | 0.4765 | Yes |
| 12 | Fzd1 | na | 3829 | 0.745 | 0.5027 | Yes |
| 13 | Gpr162 | na | 3998 | 0.728 | 0.5332 | Yes |
| 14 | Gpr37l1 | na | 4078 | 0.720 | 0.5648 | Yes |
| 15 | Gpr39 | na | 4184 | 0.712 | 0.5956 | Yes |
| 16 | Gabbr1 | na | 4256 | 0.706 | 0.6268 | Yes |
| 17 | Celsr2 | na | 4666 | 0.670 | 0.6502 | Yes |
| 18 | Prokr1 | na | 4741 | 0.664 | 0.6794 | Yes |
| 19 | Xcr1 | na | 7951 | 0.446 | 0.6428 | Yes |
| 20 | Fzd5 | na | 9285 | 0.371 | 0.6361 | Yes |
| 21 | Adrb2 | na | 9387 | 0.366 | 0.6511 | Yes |
| 22 | Fzd9 | na | 9390 | 0.366 | 0.6679 | Yes |
| 23 | Adora1 | na | 9826 | 0.343 | 0.6759 | Yes |
| 24 | S1pr5 | na | 10813 | 0.290 | 0.6717 | Yes |
| 25 | Gpr88 | na | 10959 | 0.283 | 0.6821 | Yes |
| 26 | Adgrf4 | na | 12049 | 0.231 | 0.6733 | Yes |
| 27 | Celsr3 | na | 12679 | 0.202 | 0.6714 | Yes |
| 28 | Gpr146 | na | 12890 | 0.194 | 0.6766 | Yes |
| 29 | Vipr1 | na | 13020 | 0.187 | 0.6829 | Yes |
| 30 | Smo | na | 14004 | 0.147 | 0.6721 | No |
| 31 | S1pr1 | na | 14120 | 0.142 | 0.6766 | No |
| 32 | Adora3 | na | 14298 | 0.136 | 0.6797 | No |
| 33 | Vmn1r53 | na | 15532 | 0.088 | 0.6618 | No |
| 34 | Or7e178 | na | 16931 | 0.044 | 0.6390 | No |
| 35 | Cnr1 | na | 17966 | 0.027 | 0.6218 | No |
| 36 | Ccr10 | na | 18190 | 0.024 | 0.6189 | No |
| 37 | Ltb4r2 | na | 19060 | 0.015 | 0.6041 | No |
| 38 | Or10p22 | na | 19647 | 0.010 | 0.5942 | No |
| 39 | Tmigd3 | na | 19994 | 0.008 | 0.5884 | No |
| 40 | Drd1 | na | 20323 | 0.006 | 0.5828 | No |
| 41 | Htr1d | na | 20386 | 0.006 | 0.5820 | No |
| 42 | Gpr83 | na | 20405 | 0.006 | 0.5819 | No |
| 43 | Or13a27 | na | 20862 | 0.004 | 0.5740 | No |
| 44 | Or6a2 | na | 21590 | 0.001 | 0.5611 | No |
| 45 | Oprl1 | na | 21707 | 0.000 | 0.5590 | No |
| 46 | Casr | na | 21728 | 0.000 | 0.5587 | No |
| 47 | Or13p10 | na | 21756 | 0.000 | 0.5582 | No |
| 48 | Or3a1 | na | 21861 | 0.000 | 0.5564 | No |
| 49 | Vmn1r13 | na | 21999 | 0.000 | 0.5539 | No |
| 50 | Vmn1r11 | na | 22702 | 0.000 | 0.5414 | No |
| 51 | Vmn1r47 | na | 23014 | 0.000 | 0.5359 | No |
| 52 | Or2y1b | na | 23042 | 0.000 | 0.5354 | No |
| 53 | Vmn1r10 | na | 23097 | 0.000 | 0.5345 | No |
| 54 | Or3a1c | na | 23254 | 0.000 | 0.5317 | No |
| 55 | Oprm1 | na | 23826 | 0.000 | 0.5215 | No |
| 56 | Or7e165 | na | 23913 | 0.000 | 0.5200 | No |
| 57 | Or1e16 | na | 24242 | 0.000 | 0.5142 | No |
| 58 | Htr1a | na | 24248 | 0.000 | 0.5141 | No |
| 59 | Vmn1r52 | na | 24626 | 0.000 | 0.5074 | No |
| 60 | Or8u8 | na | 24794 | 0.000 | 0.5044 | No |
| 61 | Vmn1r49 | na | 25061 | 0.000 | 0.4997 | No |
| 62 | Vmn1r48 | na | 25070 | 0.000 | 0.4995 | No |
| 63 | Or1d2 | na | 25320 | 0.000 | 0.4951 | No |
| 64 | Drd5 | na | 25431 | 0.000 | 0.4932 | No |
| 65 | Trhr2 | na | 25736 | 0.000 | 0.4878 | No |
| 66 | Vmn1r65 | na | 26746 | 0.000 | 0.4698 | No |
| 67 | Or1e34 | na | 27183 | 0.000 | 0.4621 | No |
| 68 | Or4c58 | na | 27328 | 0.000 | 0.4595 | No |
| 69 | Or1f19 | na | 27719 | 0.000 | 0.4526 | No |
| 70 | Or2w1 | na | 27895 | 0.000 | 0.4494 | No |
| 71 | Vmn1r29 | na | 28015 | 0.000 | 0.4473 | No |
| 72 | Or1e1f | na | 28217 | 0.000 | 0.4438 | No |
| 73 | Or2b6 | na | 28283 | 0.000 | 0.4426 | No |
| 74 | Vmn1r15 | na | 29380 | 0.000 | 0.4231 | No |
| 75 | Vmn1r58 | na | 29540 | 0.000 | 0.4203 | No |
| 76 | Or1m1 | na | 29822 | 0.000 | 0.4153 | No |
| 77 | Or1a1 | na | 29837 | 0.000 | 0.4150 | No |
| 78 | Vmn1r41 | na | 30167 | 0.000 | 0.4092 | No |
| 79 | Vmn1r62 | na | 30210 | 0.000 | 0.4084 | No |
| 80 | Vmn1r40 | na | 30474 | 0.000 | 0.4038 | No |
| 81 | Grm1 | na | 30812 | 0.000 | 0.3978 | No |
| 82 | Vmn1r43 | na | 31083 | 0.000 | 0.3930 | No |
| 83 | Or1x2 | na | 31136 | 0.000 | 0.3920 | No |
| 84 | Vmn1r44 | na | 32017 | 0.000 | 0.3764 | No |
| 85 | Or7a42 | na | 32159 | 0.000 | 0.3739 | No |
| 86 | Or7a40 | na | 32293 | 0.000 | 0.3715 | No |
| 87 | Or8g19 | na | 33531 | 0.000 | 0.3495 | No |
| 88 | Or7a41 | na | 33831 | 0.000 | 0.3442 | No |
| 89 | Or5g26 | na | 33937 | 0.000 | 0.3423 | No |
| 90 | Mtnr1b | na | 34354 | 0.000 | 0.3349 | No |
| 91 | Or4b1d | na | 34461 | 0.000 | 0.3330 | No |
| 92 | Or1j21 | na | 35381 | 0.000 | 0.3167 | No |
| 93 | Or1j1 | na | 35488 | 0.000 | 0.3148 | No |
| 94 | Or1p1 | na | 35591 | 0.000 | 0.3130 | No |
| 95 | Or2n1e | na | 36254 | 0.000 | 0.3012 | No |
| 96 | Gpr165 | na | 36411 | 0.000 | 0.2984 | No |
| 97 | Or1e17 | na | 36710 | 0.000 | 0.2931 | No |
| 98 | Calcr | na | 36773 | 0.000 | 0.2920 | No |
| 99 | Or6z7 | na | 37300 | 0.000 | 0.2827 | No |
| 100 | Or1e23 | na | 37966 | 0.000 | 0.2709 | No |
| 101 | Or2a57 | na | 38039 | 0.000 | 0.2696 | No |
| 102 | Vmn1r56 | na | 38211 | 0.000 | 0.2665 | No |
| 103 | Or2t1 | na | 38227 | 0.000 | 0.2663 | No |
| 104 | Or51a10 | na | 38638 | 0.000 | 0.2590 | No |
| 105 | Vmn1r25 | na | 38728 | 0.000 | 0.2574 | No |
| 106 | Or9s13 | na | 38780 | 0.000 | 0.2565 | No |
| 107 | Mrgprh | na | 38919 | 0.000 | 0.2540 | No |
| 108 | Irx6 | na | 38969 | 0.000 | 0.2532 | No |
| 109 | Vmn1r42 | na | 39104 | 0.000 | 0.2508 | No |
| 110 | Vmn2r32 | na | 39192 | 0.000 | 0.2492 | No |
| 111 | Or8g20 | na | 39557 | 0.000 | 0.2428 | No |
| 112 | Mc4r | na | 39599 | 0.000 | 0.2420 | No |
| 113 | Vmn1r63 | na | 39980 | 0.000 | 0.2353 | No |
| 114 | Vmn1r14 | na | 40195 | 0.000 | 0.2315 | No |
| 115 | Or13a18 | na | 40594 | 0.000 | 0.2244 | No |
| 116 | Or13a17 | na | 40706 | 0.000 | 0.2224 | No |
| 117 | Or51a5 | na | 41724 | 0.000 | 0.2043 | No |
| 118 | Or1e35 | na | 42104 | 0.000 | 0.1976 | No |
| 119 | Vmn1r148 | na | 42309 | 0.000 | 0.1940 | No |
| 120 | Or8d1 | na | 42800 | 0.000 | 0.1852 | No |
| 121 | Sstr5 | na | 42856 | 0.000 | 0.1843 | No |
| 122 | Vmn1r54 | na | 43234 | 0.000 | 0.1776 | No |
| 123 | Or51a39 | na | 43821 | 0.000 | 0.1671 | No |
| 124 | Or8c9 | na | 44133 | 0.000 | 0.1616 | No |
| 125 | Or7a37 | na | 44448 | 0.000 | 0.1560 | No |
| 126 | Vmn1r46 | na | 45093 | 0.000 | 0.1446 | No |
| 127 | Or2z2 | na | 45813 | 0.000 | 0.1318 | No |
| 128 | Or2a7 | na | 46120 | 0.000 | 0.1263 | No |
| 129 | Rrh | na | 46531 | 0.000 | 0.1190 | No |
| 130 | Vmn2r104 | na | 46684 | 0.000 | 0.1163 | No |
| 131 | Vmn1r172 | na | 46889 | 0.000 | 0.1127 | No |
| 132 | Vmn1r45 | na | 47008 | 0.000 | 0.1106 | No |
| 133 | Or1ad8 | na | 47337 | 0.000 | 0.1048 | No |
| 134 | Drd2 | na | 47630 | 0.000 | 0.0996 | No |
| 135 | Vmn2r107 | na | 47738 | 0.000 | 0.0977 | No |
| 136 | Or1a1b | na | 47778 | 0.000 | 0.0970 | No |
| 137 | Or6b9 | na | 48072 | 0.000 | 0.0918 | No |
| 138 | Or13a28 | na | 48450 | 0.000 | 0.0851 | No |
| 139 | V1ra8 | na | 48452 | 0.000 | 0.0851 | No |
| 140 | Vmn1r51 | na | 48591 | 0.000 | 0.0826 | No |
| 141 | Ghsr | na | 48782 | 0.000 | 0.0792 | No |
| 142 | Vmn1r50 | na | 48946 | 0.000 | 0.0763 | No |
| 143 | Vmn1r171 | na | 49017 | 0.000 | 0.0751 | No |
| 144 | Fzd7 | na | 49128 | -0.001 | 0.0732 | No |
| 145 | Pth2r | na | 49928 | -0.027 | 0.0602 | No |
| 146 | Fzd2 | na | 50465 | -0.047 | 0.0528 | No |
| 147 | Tacr3 | na | 51778 | -0.111 | 0.0346 | No |
| 148 | Gpr143 | na | 52056 | -0.127 | 0.0355 | No |
| 149 | Tas1r1 | na | 52099 | -0.130 | 0.0407 | No |
| 150 | Oprk1 | na | 52902 | -0.177 | 0.0346 | No |
| 151 | Or2ag2b | na | 53034 | -0.185 | 0.0408 | No |
| 152 | Celsr1 | na | 55333 | -0.406 | 0.0186 | No |

