Details for gene set BIOCARTA_CERAMIDE_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___Cyp2c44KO_vs_WT.RPKM_matrix___Cyp2c44KO_vs_WT.cls #Cyp2c44KO_versus_WT
Phenotype	RPKM_matrix___Cyp2c44KO_vs_WT.cls#Cyp2c44KO_versus_WT
Upregulated in class	WT
GeneSet	BIOCARTA_CERAMIDE_PATHWAY
Enrichment Score (ES)	-0.3850107
Normalized Enrichment Score (NES)	-0.7867415
Nominal p-value	0.802
FDR q-value	1.0
FWER p-Value	0.994

Fig 1: Enrichment plot: BIOCARTA_CERAMIDE_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Nsmaf	na	4943	0.343	-0.0102	No
2	Bcl2	na	5726	0.307	0.0452	No
3	Nfkb1	na	6802	0.262	0.0853	No
4	Mapk8	na	6919	0.258	0.1415	No
5	Map2k1	na	9289	0.172	0.1383	No
6	Mapk1	na	9328	0.171	0.1762	No
7	Mapk3	na	9505	0.165	0.2103	No
8	Map2k4	na	9927	0.151	0.2369	No
9	Ripk1	na	10109	0.144	0.2663	No
10	Bax	na	10594	0.130	0.2870	No
11	Raf1	na	13568	0.049	0.2453	No
12	Rela	na	13587	0.049	0.2560	No
13	Map3k1	na	15852	0.016	0.2194	No
14	Traf2	na	47959	-0.036	-0.3422	No
15	Casp8	na	49952	-0.103	-0.3543	Yes
16	Aifm1	na	51682	-0.172	-0.3461	Yes
17	Tnfrsf1a	na	51804	-0.177	-0.3084	Yes
18	Fadd	na	52518	-0.209	-0.2739	Yes
19	Smpd1	na	53715	-0.270	-0.2342	Yes
20	Tradd	na	54336	-0.307	-0.1759	Yes
21	Bad	na	54437	-0.313	-0.1069	Yes
22	Cycs	na	56222	-0.625	0.0028	Yes

Fig 2: BIOCARTA_CERAMIDE_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_CERAMIDE_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_CERAMIDE_PATHWAY