Details for gene set BIOCARTA_IGF1R_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___Cyp2c44KO_vs_WT.RPKM_matrix___Cyp2c44KO_vs_WT.cls #Cyp2c44KO_versus_WT
Phenotype	RPKM_matrix___Cyp2c44KO_vs_WT.cls#Cyp2c44KO_versus_WT
Upregulated in class	WT
GeneSet	BIOCARTA_IGF1R_PATHWAY
Enrichment Score (ES)	-0.3690845
Normalized Enrichment Score (NES)	-0.68497944
Nominal p-value	0.8962076
FDR q-value	0.8894651
FWER p-Value	0.996

Fig 1: Enrichment plot: BIOCARTA_IGF1R_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Igf1r	na	2850	0.473	0.0623	No
2	Sos1	na	7003	0.254	0.0491	No
3	Pik3ca	na	7048	0.252	0.1085	No
4	Prkar1a	na	7556	0.233	0.1550	No
5	Irs1	na	8758	0.191	0.1791	No
6	Map2k1	na	9289	0.172	0.2108	No
7	Mapk1	na	9328	0.171	0.2508	No
8	Mapk3	na	9505	0.165	0.2869	No
9	Prkacb	na	12310	0.080	0.2563	No
10	Raf1	na	13568	0.049	0.2457	No
11	Prkar1b	na	47620	-0.027	-0.3522	Yes
12	Grb2	na	47778	-0.030	-0.3477	Yes
13	Shc1	na	48130	-0.041	-0.3441	Yes
14	Pik3r1	na	49539	-0.088	-0.3481	Yes
15	Rps6ka1	na	49586	-0.090	-0.3274	Yes
16	Adcy1	na	49977	-0.104	-0.3096	Yes
17	Akt1	na	50442	-0.121	-0.2890	Yes
18	Prkar2b	na	50689	-0.131	-0.2622	Yes
19	Prkar2a	na	54189	-0.300	-0.2529	Yes
20	Bad	na	54437	-0.313	-0.1826	Yes
21	Ywhah	na	54894	-0.347	-0.1080	Yes
22	Hras	na	56113	-0.564	0.0047	Yes

Fig 2: BIOCARTA_IGF1R_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_IGF1R_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_IGF1R_PATHWAY