Details for gene set BIOCARTA_IL6_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___Cyp2c44KO_vs_WT.RPKM_matrix___Cyp2c44KO_vs_WT.cls #Cyp2c44KO_versus_WT
Phenotype	RPKM_matrix___Cyp2c44KO_vs_WT.cls#Cyp2c44KO_versus_WT
Upregulated in class	Cyp2c44KO
GeneSet	BIOCARTA_IL6_PATHWAY
Enrichment Score (ES)	0.6776669
Normalized Enrichment Score (NES)	1.3220761
Nominal p-value	0.067307696
FDR q-value	0.76340103
FWER p-Value	0.594

Fig 1: Enrichment plot: BIOCARTA_IL6_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Jun	na	157	1.020	0.1646	Yes
2	Il6	na	978	0.687	0.2627	Yes
3	Il6ra	na	1572	0.595	0.3498	Yes
4	Fos	na	2187	0.529	0.4258	Yes
5	Elk1	na	2333	0.517	0.5080	Yes
6	Cebpb	na	4110	0.388	0.5402	Yes
7	Csnk2a2	na	6335	0.280	0.5467	Yes
8	Sos1	na	7003	0.254	0.5765	Yes
9	Jak2	na	7421	0.238	0.6082	Yes
10	Map2k1	na	9289	0.172	0.6033	Yes
11	Csnk2a1	na	9481	0.166	0.6271	Yes
12	Mapk3	na	9505	0.165	0.6537	Yes
13	Jak3	na	10361	0.136	0.6609	Yes
14	Jak1	na	10922	0.120	0.6706	Yes
15	Il6st	na	11480	0.103	0.6777	Yes
16	Raf1	na	13568	0.049	0.6487	No
17	Srf	na	15004	0.025	0.6274	No
18	Stat3	na	16389	0.011	0.6047	No
19	Ptpn11	na	17701	0.004	0.5820	No
20	Grb2	na	47778	-0.030	0.0533	No
21	Shc1	na	48130	-0.041	0.0539	No
22	Hras	na	56113	-0.564	0.0047	No

Fig 2: BIOCARTA_IL6_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_IL6_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_IL6_PATHWAY