Details for gene set BIOCARTA_MAPK_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___Cyp2c44KO_vs_WT.RPKM_matrix___Cyp2c44KO_vs_WT.cls #Cyp2c44KO_versus_WT
Phenotype	RPKM_matrix___Cyp2c44KO_vs_WT.cls#Cyp2c44KO_versus_WT
Upregulated in class	Cyp2c44KO
GeneSet	BIOCARTA_MAPK_PATHWAY
Enrichment Score (ES)	0.6401837
Normalized Enrichment Score (NES)	1.2807772
Nominal p-value	0.070866145
FDR q-value	0.51590776
FWER p-Value	0.661

Fig 1: Enrichment plot: BIOCARTA_MAPK_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Jun	na	157	1.020	0.0450	Yes
2	Mapk11	na	627	0.772	0.0729	Yes
3	Map4k1	na	660	0.764	0.1081	Yes
4	Map3k6	na	808	0.721	0.1393	Yes
5	Map2k7	na	1210	0.647	0.1625	Yes
6	Map3k5	na	1264	0.636	0.1914	Yes
7	Map4k2	na	1495	0.604	0.2156	Yes
8	Map3k2	na	1794	0.570	0.2370	Yes
9	Nfkbia	na	2181	0.530	0.2550	Yes
10	Fos	na	2187	0.529	0.2797	Yes
11	Elk1	na	2333	0.517	0.3014	Yes
12	Mapk12	na	2353	0.516	0.3252	Yes
13	Map3k8	na	2594	0.494	0.3441	Yes
14	Map3k12	na	3178	0.449	0.3548	Yes
15	Map4k5	na	3306	0.442	0.3733	Yes
16	Mapkapk5	na	3372	0.435	0.3925	Yes
17	Mknk2	na	3376	0.435	0.4129	Yes
18	Map3k3	na	3481	0.428	0.4311	Yes
19	Mapk7	na	3808	0.408	0.4444	Yes
20	Mapkapk2	na	4765	0.353	0.4440	Yes
21	Tgfb1	na	4868	0.347	0.4584	Yes
22	Ikbkb	na	5353	0.323	0.4650	Yes
23	Creb1	na	5549	0.315	0.4763	Yes
24	Rps6ka3	na	5758	0.305	0.4869	Yes
25	Atf2	na	5899	0.299	0.4984	Yes
26	Rps6ka5	na	5925	0.298	0.5119	Yes
27	Daxx	na	6241	0.284	0.5197	Yes
28	Map4k4	na	6282	0.282	0.5322	Yes
29	Nfkb1	na	6802	0.262	0.5353	Yes
30	Sp1	na	6904	0.258	0.5456	Yes
31	Mapk8	na	6919	0.258	0.5574	Yes
32	Max	na	7319	0.243	0.5617	Yes
33	Rapgef2	na	7721	0.227	0.5652	Yes
34	Mknk1	na	8033	0.216	0.5698	Yes
35	Pak2	na	8306	0.207	0.5746	Yes
36	Rps6ka2	na	8911	0.185	0.5726	Yes
37	Chuk	na	8968	0.183	0.5802	Yes
38	Map3k7	na	9173	0.176	0.5848	Yes
39	Map2k1	na	9289	0.172	0.5908	Yes
40	Mapk1	na	9328	0.171	0.5982	Yes
41	Map4k3	na	9456	0.166	0.6037	Yes
42	Rps6kb1	na	9503	0.165	0.6106	Yes
43	Mapk3	na	9505	0.165	0.6183	Yes
44	Map2k4	na	9927	0.151	0.6179	Yes
45	Ripk1	na	10109	0.144	0.6215	Yes
46	Mapk9	na	10166	0.142	0.6271	Yes
47	Tgfbr1	na	10413	0.135	0.6291	Yes
48	Stat1	na	10488	0.133	0.6340	Yes
49	Rps6kb2	na	10491	0.133	0.6402	Yes
50	Mapk14	na	11085	0.115	0.6350	No
51	Tgfb3	na	11167	0.113	0.6389	No
52	Map2k5	na	11470	0.103	0.6384	No
53	Raf1	na	13568	0.049	0.6034	No
54	Rela	na	13587	0.049	0.6054	No
55	Map3k11	na	15770	0.016	0.5674	No
56	Map3k1	na	15852	0.016	0.5667	No
57	Map3k4	na	17286	0.006	0.5415	No
58	Map3k14	na	18717	0.000	0.5161	No
59	Map2k6	na	46783	-0.007	0.0180	No
60	Grb2	na	47778	-0.030	0.0018	No
61	Traf2	na	47959	-0.036	0.0002	No
62	Pak1	na	47966	-0.036	0.0018	No
63	Rps6ka4	na	47968	-0.036	0.0035	No
64	Shc1	na	48130	-0.041	0.0026	No
65	Mapk6	na	49186	-0.075	-0.0126	No
66	Rps6ka1	na	49586	-0.090	-0.0155	No
67	Cebpa	na	49762	-0.096	-0.0141	No
68	Map3k10	na	50178	-0.111	-0.0163	No
69	Tgfb2	na	51902	-0.181	-0.0384	No
70	Map2k3	na	52430	-0.205	-0.0381	No
71	Mapk10	na	53661	-0.267	-0.0475	No
72	Map2k2	na	54150	-0.297	-0.0422	No
73	Tradd	na	54336	-0.307	-0.0311	No
74	Mapk13	na	55406	-0.401	-0.0313	No
75	Myc	na	55814	-0.472	-0.0164	No
76	Hras	na	56113	-0.564	0.0047	No

Fig 2: BIOCARTA_MAPK_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_MAPK_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_MAPK_PATHWAY