Details for gene set BIOCARTA_CTLA4_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_ClusterKO.RPKM_matrix___PanKO_vs_ClusterKO.cls #PanKO_versus_ClusterKO
Phenotype	RPKM_matrix___PanKO_vs_ClusterKO.cls#PanKO_versus_ClusterKO
Upregulated in class	ClusterKO
GeneSet	BIOCARTA_CTLA4_PATHWAY
Enrichment Score (ES)	-0.72903776
Normalized Enrichment Score (NES)	-1.3029377
Nominal p-value	0.12350598
FDR q-value	1.0
FWER p-Value	0.604

Fig 1: Enrichment plot: BIOCARTA_CTLA4_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Ctla4	na	5521	0.183	-0.0613	No
2	Ptpn11	na	8897	0.068	-0.1076	No
3	Grb2	na	42417	-0.041	-0.6941	No
4	Pik3ca	na	44386	-0.092	-0.7107	Yes
5	Cd80	na	44669	-0.101	-0.6955	Yes
6	Cd3g	na	45374	-0.121	-0.6839	Yes
7	Il2	na	45987	-0.140	-0.6667	Yes
8	Cd86	na	46525	-0.158	-0.6447	Yes
9	Cd3e	na	49243	-0.253	-0.6424	Yes
10	Itk	na	52409	-0.393	-0.6199	Yes
11	Lck	na	53081	-0.434	-0.5451	Yes
12	Cd247	na	54418	-0.532	-0.4624	Yes
13	Cd3d	na	54545	-0.545	-0.3557	Yes
14	Icos	na	54574	-0.548	-0.2466	Yes
15	Pik3r1	na	54770	-0.569	-0.1363	Yes
16	Cd28	na	56079	-0.824	0.0053	Yes

Fig 2: BIOCARTA_CTLA4_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_CTLA4_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_CTLA4_PATHWAY