Details for gene set BIOCARTA_IL6_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_ClusterKO.RPKM_matrix___PanKO_vs_ClusterKO.cls #PanKO_versus_ClusterKO
Phenotype	RPKM_matrix___PanKO_vs_ClusterKO.cls#PanKO_versus_ClusterKO
Upregulated in class	PanKO
GeneSet	BIOCARTA_IL6_PATHWAY
Enrichment Score (ES)	0.4681975
Normalized Enrichment Score (NES)	0.9267555
Nominal p-value	0.5557692
FDR q-value	1.0
FWER p-Value	0.925

Fig 1: Enrichment plot: BIOCARTA_IL6_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Hras	na	295	0.620	0.1377	Yes
2	Stat3	na	1239	0.439	0.2220	Yes
3	Jun	na	1362	0.424	0.3176	Yes
4	Srf	na	1874	0.376	0.3953	Yes
5	Fos	na	2257	0.346	0.4682	Yes
6	Cebpb	na	6010	0.164	0.4395	No
7	Csnk2a2	na	8165	0.089	0.4217	No
8	Ptpn11	na	8897	0.068	0.4245	No
9	Mapk3	na	9547	0.049	0.4242	No
10	Elk1	na	9582	0.048	0.4347	No
11	Il6	na	39643	-0.005	-0.0976	No
12	Il6ra	na	42297	-0.038	-0.1360	No
13	Grb2	na	42417	-0.041	-0.1287	No
14	Jak3	na	42455	-0.042	-0.1197	No
15	Raf1	na	42592	-0.044	-0.1119	No
16	Shc1	na	43680	-0.071	-0.1148	No
17	Jak1	na	44019	-0.080	-0.1023	No
18	Il6st	na	45998	-0.140	-0.1051	No
19	Jak2	na	46694	-0.163	-0.0798	No
20	Map2k1	na	48705	-0.232	-0.0621	No
21	Csnk2a1	na	51724	-0.357	-0.0333	No
22	Sos1	na	54092	-0.503	0.0405	No

Fig 2: BIOCARTA_IL6_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_IL6_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_IL6_PATHWAY