| Dataset | RPKM_matrix___PanKO_vs_ClusterKO.RPKM_matrix___PanKO_vs_ClusterKO.cls #PanKO_versus_ClusterKO |
| Phenotype | RPKM_matrix___PanKO_vs_ClusterKO.cls#PanKO_versus_ClusterKO |
| Upregulated in class | ClusterKO |
| GeneSet | WP_GPCRS_OTHER |
| Enrichment Score (ES) | -0.62890565 |
| Normalized Enrichment Score (NES) | -1.3464186 |
| Nominal p-value | 0.054766733 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.633 |

| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | Gpr39 | na | 571 | 0.544 | 0.0280 | No |
| 2 | Fzd9 | na | 634 | 0.532 | 0.0642 | No |
| 3 | Fzd2 | na | 2129 | 0.356 | 0.0626 | No |
| 4 | Oprk1 | na | 4636 | 0.217 | 0.0332 | No |
| 5 | Celsr3 | na | 4979 | 0.203 | 0.0414 | No |
| 6 | Gpr84 | na | 7204 | 0.122 | 0.0104 | No |
| 7 | S1pr2 | na | 7253 | 0.121 | 0.0180 | No |
| 8 | Gpr34 | na | 7268 | 0.120 | 0.0262 | No |
| 9 | Gpr37l1 | na | 8926 | 0.067 | 0.0014 | No |
| 10 | Adgrg1 | na | 9776 | 0.042 | -0.0107 | No |
| 11 | Prokr1 | na | 9793 | 0.042 | -0.0081 | No |
| 12 | Htr1d | na | 9899 | 0.039 | -0.0072 | No |
| 13 | Celsr2 | na | 10862 | 0.016 | -0.0232 | No |
| 14 | Gpr143 | na | 11221 | 0.010 | -0.0289 | No |
| 15 | Rrh | na | 11726 | 0.004 | -0.0376 | No |
| 16 | Sstr5 | na | 11771 | 0.004 | -0.0381 | No |
| 17 | Or13a18 | na | 11921 | 0.002 | -0.0406 | No |
| 18 | Grm1 | na | 11948 | 0.002 | -0.0410 | No |
| 19 | Or13p10 | na | 12100 | 0.000 | -0.0436 | No |
| 20 | Or3a1 | na | 12202 | 0.000 | -0.0454 | No |
| 21 | Vmn1r13 | na | 12343 | 0.000 | -0.0479 | No |
| 22 | Vmn1r11 | na | 13014 | 0.000 | -0.0599 | No |
| 23 | Vmn1r47 | na | 13318 | 0.000 | -0.0652 | No |
| 24 | Or2y1b | na | 13346 | 0.000 | -0.0657 | No |
| 25 | Vmn1r10 | na | 13397 | 0.000 | -0.0666 | No |
| 26 | Or3a1c | na | 13548 | 0.000 | -0.0693 | No |
| 27 | Mrgprh | na | 13736 | 0.000 | -0.0726 | No |
| 28 | Irx6 | na | 13786 | 0.000 | -0.0735 | No |
| 29 | Vmn1r42 | na | 13918 | 0.000 | -0.0758 | No |
| 30 | Vmn2r32 | na | 13999 | 0.000 | -0.0772 | No |
| 31 | Or8g20 | na | 14358 | 0.000 | -0.0836 | No |
| 32 | Mc4r | na | 14399 | 0.000 | -0.0843 | No |
| 33 | Vmn1r63 | na | 14770 | 0.000 | -0.0909 | No |
| 34 | Vmn1r14 | na | 14976 | 0.000 | -0.0945 | No |
| 35 | Vmn1r46 | na | 15547 | 0.000 | -0.1047 | No |
| 36 | Oprm1 | na | 16566 | 0.000 | -0.1228 | No |
| 37 | Or7e165 | na | 16652 | 0.000 | -0.1243 | No |
| 38 | Or1e16 | na | 16974 | 0.000 | -0.1300 | No |
| 39 | Htr1a | na | 16980 | 0.000 | -0.1301 | No |
| 40 | Vmn1r52 | na | 17343 | 0.000 | -0.1365 | No |
| 41 | Or8u8 | na | 17508 | 0.000 | -0.1394 | No |
| 42 | Or7a41 | na | 17897 | 0.000 | -0.1463 | No |
| 43 | Or5g26 | na | 17999 | 0.000 | -0.1481 | No |
| 44 | Mtnr1b | na | 18410 | 0.000 | -0.1554 | No |
| 45 | Or4b1d | na | 18513 | 0.000 | -0.1572 | No |
| 46 | Or1j21 | na | 19400 | 0.000 | -0.1730 | No |
| 47 | Or1j1 | na | 19501 | 0.000 | -0.1748 | No |
| 48 | Or1p1 | na | 19601 | 0.000 | -0.1765 | No |
| 49 | Vmn1r49 | na | 20255 | 0.000 | -0.1882 | No |
| 50 | Vmn1r48 | na | 20263 | 0.000 | -0.1883 | No |
| 51 | Or1d2 | na | 20506 | 0.000 | -0.1926 | No |
| 52 | Drd5 | na | 20613 | 0.000 | -0.1945 | No |
| 53 | Trhr2 | na | 20912 | 0.000 | -0.1998 | No |
| 54 | Or8g19 | na | 21885 | 0.000 | -0.2171 | No |
| 55 | Or13a17 | na | 22005 | 0.000 | -0.2192 | No |
| 56 | Or51a5 | na | 22982 | 0.000 | -0.2365 | No |
| 57 | Or1e35 | na | 23357 | 0.000 | -0.2432 | No |
| 58 | Vmn1r148 | na | 23557 | 0.000 | -0.2467 | No |
| 59 | Or8d1 | na | 24036 | 0.000 | -0.2552 | No |
| 60 | Vmn1r65 | na | 24295 | 0.000 | -0.2598 | No |
| 61 | Or1e34 | na | 24718 | 0.000 | -0.2673 | No |
| 62 | Or4c58 | na | 24861 | 0.000 | -0.2698 | No |
| 63 | Or1f19 | na | 25240 | 0.000 | -0.2766 | No |
| 64 | Or2w1 | na | 25409 | 0.000 | -0.2796 | No |
| 65 | Vmn1r29 | na | 25526 | 0.000 | -0.2816 | No |
| 66 | Or1e1f | na | 25726 | 0.000 | -0.2852 | No |
| 67 | Or2b6 | na | 25790 | 0.000 | -0.2863 | No |
| 68 | Vmn1r15 | na | 26862 | 0.000 | -0.3053 | No |
| 69 | Vmn1r58 | na | 27016 | 0.000 | -0.3080 | No |
| 70 | Or1m1 | na | 27286 | 0.000 | -0.3128 | No |
| 71 | Or1a1 | na | 27301 | 0.000 | -0.3131 | No |
| 72 | Vmn1r41 | na | 27620 | 0.000 | -0.3187 | No |
| 73 | Vmn1r62 | na | 27663 | 0.000 | -0.3195 | No |
| 74 | Vmn1r40 | na | 27921 | 0.000 | -0.3241 | No |
| 75 | Vmn1r43 | na | 28515 | 0.000 | -0.3346 | No |
| 76 | Or1x2 | na | 28564 | 0.000 | -0.3355 | No |
| 77 | Vmn1r44 | na | 29429 | 0.000 | -0.3508 | No |
| 78 | Or7a42 | na | 29567 | 0.000 | -0.3533 | No |
| 79 | Or7a40 | na | 29697 | 0.000 | -0.3556 | No |
| 80 | Vmn1r54 | na | 31081 | 0.000 | -0.3801 | No |
| 81 | Or2n1e | na | 31296 | 0.000 | -0.3840 | No |
| 82 | Gpr165 | na | 31450 | 0.000 | -0.3867 | No |
| 83 | Or1e17 | na | 31737 | 0.000 | -0.3918 | No |
| 84 | Calcr | na | 31798 | 0.000 | -0.3928 | No |
| 85 | Or6z7 | na | 32320 | 0.000 | -0.4021 | No |
| 86 | Or1e23 | na | 32961 | 0.000 | -0.4135 | No |
| 87 | Or2a57 | na | 33033 | 0.000 | -0.4147 | No |
| 88 | Vmn1r56 | na | 33208 | 0.000 | -0.4178 | No |
| 89 | Or2t1 | na | 33224 | 0.000 | -0.4181 | No |
| 90 | Or51a10 | na | 33621 | 0.000 | -0.4251 | No |
| 91 | Vmn1r25 | na | 33708 | 0.000 | -0.4267 | No |
| 92 | Or9s13 | na | 33754 | 0.000 | -0.4275 | No |
| 93 | Or2z2 | na | 33942 | 0.000 | -0.4308 | No |
| 94 | Or2a7 | na | 34238 | 0.000 | -0.4360 | No |
| 95 | Vmn2r104 | na | 34782 | 0.000 | -0.4457 | No |
| 96 | Vmn1r172 | na | 34989 | 0.000 | -0.4494 | No |
| 97 | Vmn1r45 | na | 35107 | 0.000 | -0.4514 | No |
| 98 | Or1ad8 | na | 35429 | 0.000 | -0.4572 | No |
| 99 | Drd2 | na | 35712 | 0.000 | -0.4622 | No |
| 100 | Vmn2r107 | na | 35816 | 0.000 | -0.4640 | No |
| 101 | Or1a1b | na | 35855 | 0.000 | -0.4647 | No |
| 102 | Or6b9 | na | 36151 | 0.000 | -0.4699 | No |
| 103 | Or51a39 | na | 36906 | 0.000 | -0.4833 | No |
| 104 | Or8c9 | na | 37207 | 0.000 | -0.4887 | No |
| 105 | Or7a37 | na | 37515 | 0.000 | -0.4941 | No |
| 106 | Or13a28 | na | 38087 | 0.000 | -0.5043 | No |
| 107 | V1ra8 | na | 38089 | 0.000 | -0.5043 | No |
| 108 | Vmn1r51 | na | 38224 | 0.000 | -0.5067 | No |
| 109 | Ghsr | na | 38414 | 0.000 | -0.5101 | No |
| 110 | Vmn1r50 | na | 38575 | 0.000 | -0.5129 | No |
| 111 | Vmn1r171 | na | 38642 | 0.000 | -0.5141 | No |
| 112 | Casr | na | 38742 | -0.000 | -0.5158 | No |
| 113 | Oprl1 | na | 38761 | -0.000 | -0.5161 | No |
| 114 | Or6a2 | na | 38847 | -0.001 | -0.5176 | No |
| 115 | Ccr10 | na | 39421 | -0.004 | -0.5275 | No |
| 116 | Or7e178 | na | 39601 | -0.004 | -0.5304 | No |
| 117 | Tacr3 | na | 39762 | -0.005 | -0.5328 | No |
| 118 | Drd1 | na | 39846 | -0.006 | -0.5339 | No |
| 119 | Tmigd3 | na | 40088 | -0.008 | -0.5376 | No |
| 120 | Pth2r | na | 41726 | -0.027 | -0.5648 | No |
| 121 | Cnr1 | na | 43199 | -0.058 | -0.5869 | No |
| 122 | Xcr1 | na | 44229 | -0.087 | -0.5991 | No |
| 123 | Fzd1 | na | 44357 | -0.091 | -0.5950 | No |
| 124 | Fzd7 | na | 45676 | -0.131 | -0.6093 | No |
| 125 | Vmn1r53 | na | 46780 | -0.166 | -0.6173 | Yes |
| 126 | Or10p22 | na | 47163 | -0.178 | -0.6116 | Yes |
| 127 | Or2ag2b | na | 47521 | -0.190 | -0.6046 | Yes |
| 128 | Adrb2 | na | 47547 | -0.191 | -0.5917 | Yes |
| 129 | Gabbr1 | na | 49213 | -0.251 | -0.6037 | Yes |
| 130 | Fzd5 | na | 49288 | -0.254 | -0.5872 | Yes |
| 131 | Cysltr1 | na | 49320 | -0.255 | -0.5699 | Yes |
| 132 | Ccr7 | na | 50402 | -0.300 | -0.5680 | Yes |
| 133 | Gpr88 | na | 50625 | -0.308 | -0.5504 | Yes |
| 134 | Ednra | na | 51119 | -0.331 | -0.5359 | Yes |
| 135 | Or13a27 | na | 51207 | -0.335 | -0.5140 | Yes |
| 136 | Celsr1 | na | 51477 | -0.346 | -0.4945 | Yes |
| 137 | Adora1 | na | 51579 | -0.351 | -0.4717 | Yes |
| 138 | Tas1r1 | na | 51689 | -0.356 | -0.4487 | Yes |
| 139 | Ltb4r2 | na | 52050 | -0.374 | -0.4288 | Yes |
| 140 | Smo | na | 52442 | -0.395 | -0.4081 | Yes |
| 141 | Gpr132 | na | 52744 | -0.413 | -0.3845 | Yes |
| 142 | Adgre5 | na | 53101 | -0.435 | -0.3603 | Yes |
| 143 | Gpr83 | na | 53162 | -0.439 | -0.3306 | Yes |
| 144 | Gpr162 | na | 53211 | -0.442 | -0.3004 | Yes |
| 145 | Adrb1 | na | 53706 | -0.474 | -0.2760 | Yes |
| 146 | Gpr146 | na | 53751 | -0.477 | -0.2433 | Yes |
| 147 | Adgrf4 | na | 53767 | -0.478 | -0.2100 | Yes |
| 148 | S1pr1 | na | 54151 | -0.508 | -0.1812 | Yes |
| 149 | Adora3 | na | 54821 | -0.574 | -0.1528 | Yes |
| 150 | Ackr1 | na | 55243 | -0.628 | -0.1163 | Yes |
| 151 | S1pr5 | na | 56164 | -0.870 | -0.0716 | Yes |
| 152 | Vipr1 | na | 56312 | -1.075 | 0.0012 | Yes |

