Details for gene set WP_TRYPTOPHAN_METABOLISM[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_ClusterKO.RPKM_matrix___PanKO_vs_ClusterKO.cls #PanKO_versus_ClusterKO
Phenotype	RPKM_matrix___PanKO_vs_ClusterKO.cls#PanKO_versus_ClusterKO
Upregulated in class	ClusterKO
GeneSet	WP_TRYPTOPHAN_METABOLISM
Enrichment Score (ES)	-0.5940987
Normalized Enrichment Score (NES)	-1.2860318
Nominal p-value	0.08350731
FDR q-value	0.82336193
FWER p-Value	0.752

Fig 1: Enrichment plot: WP_TRYPTOPHAN_METABOLISM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Rnf25	na	1606	0.400	0.0088	No
2	Mdm2	na	1925	0.372	0.0379	No
3	Asmt	na	2494	0.331	0.0587	No
4	Aldh1a2	na	4005	0.245	0.0547	No
5	Aox1	na	5992	0.165	0.0349	No
6	Prmt1	na	6702	0.139	0.0352	No
7	Cyp7b1	na	7188	0.123	0.0381	No
8	Dhcr24	na	7858	0.100	0.0356	No
9	Acat1	na	8839	0.070	0.0247	No
10	Wars1	na	9221	0.058	0.0233	No
11	Aadat	na	9572	0.048	0.0216	No
12	Cyp1b1	na	10760	0.017	0.0022	No
13	Ogdh	na	11374	0.008	-0.0080	No
14	Tph1	na	16550	0.000	-0.0998	No
15	Cyp19a1	na	31848	0.000	-0.3714	No
16	Aanat	na	39126	-0.002	-0.5004	No
17	Cyp1a1	na	40027	-0.007	-0.5157	No
18	Aoc1	na	43152	-0.057	-0.5658	No
19	Ubr5	na	44032	-0.081	-0.5738	No
20	Aldh2	na	44121	-0.084	-0.5676	No
21	Aldh3a2	na	44236	-0.087	-0.5615	No
22	Cyp2f2	na	44441	-0.093	-0.5564	No
23	Aldh1a1	na	45521	-0.125	-0.5639	No
24	Cyp1a2	na	46967	-0.172	-0.5735	No
25	Cyp2c55	na	48129	-0.212	-0.5744	Yes
26	Hadh	na	48145	-0.212	-0.5548	Yes
27	Acmsd	na	48242	-0.216	-0.5364	Yes
28	Maob	na	48926	-0.240	-0.5261	Yes
29	Aldh9a1	na	49456	-0.260	-0.5112	Yes
30	Cyp2j6	na	49530	-0.264	-0.4879	Yes
31	Haao	na	49575	-0.265	-0.4639	Yes
32	Hsd17b10	na	49720	-0.272	-0.4411	Yes
33	Ddc	na	51572	-0.351	-0.4413	Yes
34	Ido1	na	51845	-0.363	-0.4122	Yes
35	Gcdh	na	52238	-0.384	-0.3834	Yes
36	Inmt	na	52406	-0.393	-0.3497	Yes
37	Kynu	na	52547	-0.401	-0.3147	Yes
38	Echs1	na	53040	-0.431	-0.2832	Yes
39	Cyp4f14	na	53593	-0.467	-0.2495	Yes
40	Cat	na	54354	-0.527	-0.2138	Yes
41	Ube3a	na	55108	-0.610	-0.1703	Yes
42	Cyp2e1	na	55206	-0.623	-0.1139	Yes
43	Tdo2	na	55692	-0.705	-0.0567	Yes
44	Afmid	na	55808	-0.737	0.0101	Yes

Fig 2: WP_TRYPTOPHAN_METABOLISM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_TRYPTOPHAN_METABOLISM: Random ES distribution   
Gene set null distribution of ES for WP_TRYPTOPHAN_METABOLISM