Details for gene set BIOCARTA_BAD_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_Cyp2c44KO.RPKM_matrix___PanKO_vs_Cyp2c44KO.cls #PanKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___PanKO_vs_Cyp2c44KO.cls#PanKO_versus_Cyp2c44KO
Upregulated in class	PanKO
GeneSet	BIOCARTA_BAD_PATHWAY
Enrichment Score (ES)	0.81970984
Normalized Enrichment Score (NES)	1.356752
Nominal p-value	0.008196721
FDR q-value	0.17656605
FWER p-Value	0.396

Fig 1: Enrichment plot: BIOCARTA_BAD_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Ywhah	na	281	1.346	0.1070	Yes
2	Prkar1b	na	601	1.153	0.1973	Yes
3	Akt1	na	1523	0.861	0.2527	Yes
4	Csf2rb	na	1545	0.857	0.3236	Yes
5	Bax	na	1615	0.841	0.3924	Yes
6	Prkar2b	na	2112	0.755	0.4464	Yes
7	Adcy1	na	2719	0.671	0.4915	Yes
8	Bcl2	na	2720	0.671	0.5473	Yes
9	Pik3cg	na	2908	0.644	0.5977	Yes
10	Kitl	na	2995	0.633	0.6488	Yes
11	Mapk3	na	3072	0.625	0.6995	Yes
12	Rps6ka1	na	3188	0.612	0.7484	Yes
13	Bad	na	3394	0.588	0.7937	Yes
14	Il3ra	na	5296	0.431	0.7958	Yes
15	Prkar1a	na	5813	0.397	0.8197	Yes
16	Pik3ca	na	11644	0.115	0.7259	No
17	Igf1r	na	11860	0.106	0.7309	No
18	Prkar2a	na	12264	0.093	0.7315	No
19	Mapk1	na	12870	0.070	0.7266	No
20	Il3	na	39567	0.000	0.2529	No
21	Prkacb	na	45858	-0.039	0.1445	No
22	Igf1	na	47677	-0.103	0.1209	No
23	Pik3r1	na	48173	-0.125	0.1226	No
24	Kit	na	51094	-0.277	0.0937	No

Fig 2: BIOCARTA_BAD_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_BAD_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_BAD_PATHWAY