Details for gene set BIOCARTA_P53_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_Cyp2c44KO.RPKM_matrix___PanKO_vs_Cyp2c44KO.cls #PanKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___PanKO_vs_Cyp2c44KO.cls#PanKO_versus_Cyp2c44KO
Upregulated in class	PanKO
GeneSet	BIOCARTA_P53_PATHWAY
Enrichment Score (ES)	0.8340565
Normalized Enrichment Score (NES)	1.3417464
Nominal p-value	0.021611001
FDR q-value	0.19539294
FWER p-Value	0.452

Fig 1: Enrichment plot: BIOCARTA_P53_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Ccne1	na	1508	0.865	0.0809	Yes
2	Bax	na	1615	0.841	0.1838	Yes
3	Cdk4	na	2085	0.759	0.2700	Yes
4	Apaf1	na	2236	0.739	0.3594	Yes
5	Trp53	na	2516	0.700	0.4415	Yes
6	Bcl2	na	2720	0.671	0.5214	Yes
7	Pcna	na	3544	0.573	0.5781	Yes
8	Gadd45a	na	3971	0.534	0.6371	Yes
9	Ccnd1	na	4196	0.513	0.6970	Yes
10	Timp3	na	4583	0.484	0.7504	Yes
11	Mdm2	na	5278	0.432	0.7919	Yes
12	E2f1	na	6145	0.379	0.8237	Yes
13	Cdk2	na	7628	0.295	0.8341	Yes
14	Cdkn1a	na	12260	0.093	0.7635	No
15	Rb1	na	48808	-0.154	0.1343	No

Fig 2: BIOCARTA_P53_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_P53_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_P53_PATHWAY