Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | RPKM_matrix___PanKO_vs_Cyp2c44KO.RPKM_matrix___PanKO_vs_Cyp2c44KO.cls #PanKO_versus_Cyp2c44KO |
| Phenotype | RPKM_matrix___PanKO_vs_Cyp2c44KO.cls#PanKO_versus_Cyp2c44KO |
| Upregulated in class | PanKO |
| GeneSet | REACTOME_DEFENSINS |
| Enrichment Score (ES) | 0.81110394 |
| Normalized Enrichment Score (NES) | 1.5141908 |
| Nominal p-value | 0.004310345 |
| FDR q-value | 0.66409826 |
| FWER p-Value | 0.206 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | Tlr2 | na | 191 | 1.424 | 0.3449 | Yes |
| 2 | Tlr1 | na | 246 | 1.379 | 0.6811 | Yes |
| 3 | Defb1 | na | 2533 | 0.698 | 0.8111 | Yes |
| 4 | Defa25 | na | 16748 | 0.000 | 0.5587 | No |
| 5 | Defa29 | na | 17092 | 0.000 | 0.5526 | No |
| 6 | Defa23 | na | 17560 | 0.000 | 0.5444 | No |
| 7 | Defa2 | na | 18053 | 0.000 | 0.5356 | No |
| 8 | Defa5 | na | 18146 | 0.000 | 0.5340 | No |
| 9 | Defa17 | na | 18876 | 0.000 | 0.5210 | No |
| 10 | Defb28 | na | 19083 | 0.000 | 0.5174 | No |
| 11 | Defa36 | na | 19205 | 0.000 | 0.5152 | No |
| 12 | Defb19 | na | 19907 | 0.000 | 0.5028 | No |
| 13 | Try10 | na | 20668 | 0.000 | 0.4893 | No |
| 14 | Defa24 | na | 21007 | 0.000 | 0.4833 | No |
| 15 | Defa31 | na | 21726 | 0.000 | 0.4706 | No |
| 16 | Try5 | na | 22057 | 0.000 | 0.4647 | No |
| 17 | Prss1 | na | 22705 | 0.000 | 0.4532 | No |
| 18 | Defa27 | na | 23161 | 0.000 | 0.4451 | No |
| 19 | Defa41 | na | 23597 | 0.000 | 0.4374 | No |
| 20 | Defb36 | na | 24968 | 0.000 | 0.4131 | No |
| 21 | Defa28 | na | 25104 | 0.000 | 0.4107 | No |
| 22 | Gm5771 | na | 25644 | 0.000 | 0.4011 | No |
| 23 | Defb18 | na | 26929 | 0.000 | 0.3783 | No |
| 24 | Defb43 | na | 29256 | 0.000 | 0.3370 | No |
| 25 | Defa35 | na | 29341 | 0.000 | 0.3355 | No |
| 26 | Defa39 | na | 29617 | 0.000 | 0.3306 | No |
| 27 | Gm10334 | na | 30417 | 0.000 | 0.3165 | No |
| 28 | Defa3 | na | 30580 | 0.000 | 0.3136 | No |
| 29 | Prss3 | na | 30853 | 0.000 | 0.3088 | No |
| 30 | Defb42 | na | 30939 | 0.000 | 0.3072 | No |
| 31 | Defb4 | na | 31409 | 0.000 | 0.2989 | No |
| 32 | Defa32 | na | 31673 | 0.000 | 0.2942 | No |
| 33 | Defa26 | na | 32153 | 0.000 | 0.2857 | No |
| 34 | Defb47 | na | 32629 | 0.000 | 0.2773 | No |
| 35 | Defb21 | na | 33182 | 0.000 | 0.2675 | No |
| 36 | Art1 | na | 33278 | 0.000 | 0.2658 | No |
| 37 | Defa37 | na | 33535 | 0.000 | 0.2613 | No |
| 38 | Defb48 | na | 34609 | 0.000 | 0.2422 | No |
| 39 | Defa38 | na | 35521 | 0.000 | 0.2260 | No |
| 40 | Defb14 | na | 35812 | 0.000 | 0.2209 | No |
| 41 | Defa20 | na | 35878 | 0.000 | 0.2197 | No |
| 42 | Defa22 | na | 35905 | 0.000 | 0.2193 | No |
| 43 | Defb30 | na | 36347 | 0.000 | 0.2115 | No |
| 44 | Defa42 | na | 37072 | 0.000 | 0.1986 | No |
| 45 | Defa40 | na | 37253 | 0.000 | 0.1954 | No |
| 46 | AY761185 | na | 37937 | 0.000 | 0.1833 | No |
| 47 | Defa43 | na | 38803 | 0.000 | 0.1679 | No |
| 48 | Defa21 | na | 42069 | 0.000 | 0.1100 | No |
| 49 | Try4 | na | 44027 | -0.008 | 0.0771 | No |
| 50 | Defa34 | na | 45470 | -0.029 | 0.0587 | No |
| 51 | Defa30 | na | 45492 | -0.030 | 0.0656 | No |
| 52 | Prss2 | na | 45809 | -0.037 | 0.0691 | No |
| 53 | Cd4 | na | 47878 | -0.113 | 0.0600 | No |
| 54 | Ccr6 | na | 49324 | -0.179 | 0.0780 | No |
| 55 | Defb25 | na | 49595 | -0.193 | 0.1204 | No |
