Details for gene set REACTOME_PYRUVATE_METABOLISM[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_Cyp2c44KO.RPKM_matrix___PanKO_vs_Cyp2c44KO.cls #PanKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___PanKO_vs_Cyp2c44KO.cls#PanKO_versus_Cyp2c44KO
Upregulated in class	Cyp2c44KO
GeneSet	REACTOME_PYRUVATE_METABOLISM
Enrichment Score (ES)	-0.52643406
Normalized Enrichment Score (NES)	-1.1473564
Nominal p-value	0.25502008
FDR q-value	1.0
FWER p-Value	0.975

Fig 1: Enrichment plot: REACTOME_PYRUVATE_METABOLISM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Pdp1	na	496	1.202	0.1107	No
2	Ldha	na	1623	0.839	0.1741	No
3	Pdk3	na	2177	0.747	0.2385	No
4	Pdhx	na	7009	0.327	0.1853	No
5	Pdhb	na	9180	0.223	0.1690	No
6	Vdac1	na	11513	0.120	0.1396	No
7	Dld	na	11828	0.108	0.1447	No
8	Pdk4	na	13733	0.042	0.1150	No
9	Ldhc	na	18188	0.000	0.0360	No
10	Pdha2	na	28630	0.000	-0.1493	No
11	Ppard	na	44551	-0.014	-0.4304	No
12	Pdha1	na	44890	-0.018	-0.4346	No
13	Rxra	na	48758	-0.152	-0.4882	No
14	Ldhb	na	50916	-0.265	-0.5001	Yes
15	Me1	na	51195	-0.282	-0.4770	Yes
16	Dlat	na	51487	-0.300	-0.4523	Yes
17	Hagh	na	52101	-0.343	-0.4291	Yes
18	Glo1	na	53112	-0.424	-0.4048	Yes
19	Gstz1	na	54210	-0.543	-0.3703	Yes
20	Pdpr	na	54897	-0.655	-0.3173	Yes
21	Pdp2	na	55340	-0.764	-0.2492	Yes
22	Pdk1	na	55364	-0.772	-0.1729	Yes
23	Pdk2	na	55647	-0.865	-0.0918	Yes
24	Ldhal6b	na	55995	-1.054	0.0068	Yes

Fig 2: REACTOME_PYRUVATE_METABOLISM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_PYRUVATE_METABOLISM: Random ES distribution   
Gene set null distribution of ES for REACTOME_PYRUVATE_METABOLISM