Details for gene set WP_PROTEASOME_DEGRADATION[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_Cyp2c44KO.RPKM_matrix___PanKO_vs_Cyp2c44KO.cls #PanKO_versus_Cyp2c44KO
Phenotype	RPKM_matrix___PanKO_vs_Cyp2c44KO.cls#PanKO_versus_Cyp2c44KO
Upregulated in class	PanKO
GeneSet	WP_PROTEASOME_DEGRADATION
Enrichment Score (ES)	0.74688786
Normalized Enrichment Score (NES)	1.4025185
Nominal p-value	0.027888447
FDR q-value	0.14554031
FWER p-Value	0.414

Fig 1: Enrichment plot: WP_PROTEASOME_DEGRADATION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Psmd8	na	1372	0.895	0.0225	Yes
2	Rpn1	na	1427	0.883	0.0678	Yes
3	Ubb	na	1548	0.856	0.1105	Yes
4	H2ax	na	1651	0.832	0.1522	Yes
5	Psmd13	na	2078	0.760	0.1845	Yes
6	Rpn2	na	2853	0.650	0.2048	Yes
7	Psmb10	na	3277	0.601	0.2287	Yes
8	H2az1	na	3481	0.579	0.2555	Yes
9	Psme2	na	3824	0.548	0.2781	Yes
10	Psme1	na	4496	0.490	0.2918	Yes
11	Psmc5	na	4532	0.488	0.3167	Yes
12	Uchl1	na	4646	0.479	0.3398	Yes
13	Psme3	na	4660	0.478	0.3646	Yes
14	Psma2	na	4878	0.463	0.3850	Yes
15	Psmb2	na	4962	0.456	0.4074	Yes
16	Ube2d2a	na	5279	0.432	0.4244	Yes
17	Psma5	na	5425	0.421	0.4439	Yes
18	Psmd7	na	5522	0.414	0.4639	Yes
19	Uchl4	na	5560	0.413	0.4849	Yes
20	Psmc6	na	5703	0.403	0.5035	Yes
21	Psmb6	na	5917	0.391	0.5201	Yes
22	Psmd12	na	5931	0.390	0.5403	Yes
23	Psmc4	na	6040	0.385	0.5586	Yes
24	Psmd5	na	6405	0.362	0.5711	Yes
25	Psmc2	na	6576	0.352	0.5865	Yes
26	Psma4	na	6721	0.344	0.6019	Yes
27	Psma3	na	6785	0.341	0.6186	Yes
28	Psmd6	na	6865	0.336	0.6348	Yes
29	Psmc3	na	7192	0.318	0.6456	Yes
30	Psmd4	na	7309	0.312	0.6599	Yes
31	Ube2d3	na	7500	0.302	0.6724	Yes
32	Psmb5	na	7538	0.300	0.6874	Yes
33	Psmd2	na	7577	0.298	0.7023	Yes
34	Psmb4	na	7929	0.280	0.7108	Yes
35	Ube2d1	na	8284	0.264	0.7183	Yes
36	Nedd4	na	8328	0.262	0.7312	Yes
37	Psmd11	na	8421	0.257	0.7431	Yes
38	Psmb7	na	9216	0.222	0.7406	Yes
39	Psma7	na	9495	0.210	0.7466	Yes
40	Uba1	na	10034	0.187	0.7469	Yes
41	Psmb1	na	11645	0.115	0.7243	No
42	Psmc1	na	11833	0.107	0.7266	No
43	Psma6	na	12148	0.095	0.7261	No
44	Psmb9	na	13018	0.065	0.7141	No
45	H2ac22	na	13679	0.043	0.7046	No
46	Ube2b	na	46422	-0.055	0.1262	No
47	Psmd9	na	48398	-0.135	0.0982	No
48	Uba7	na	49253	-0.175	0.0922	No
49	Psmd3	na	49379	-0.182	0.0995	No
50	H2-Q10	na	50068	-0.217	0.0986	No
51	Ifng	na	50728	-0.255	0.1003	No

Fig 2: WP_PROTEASOME_DEGRADATION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_PROTEASOME_DEGRADATION: Random ES distribution   
Gene set null distribution of ES for WP_PROTEASOME_DEGRADATION