Details for gene set BIOCARTA_IL6_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_WT.RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Phenotype	RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Upregulated in class	PanKO
GeneSet	BIOCARTA_IL6_PATHWAY
Enrichment Score (ES)	0.8205863
Normalized Enrichment Score (NES)	1.3671674
Nominal p-value	0.007751938
FDR q-value	0.087741725
FWER p-Value	0.331

Fig 1: Enrichment plot: BIOCARTA_IL6_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Fos	na	1014	1.036	0.0685	Yes
2	Stat3	na	1250	0.963	0.1448	Yes
3	Jun	na	1278	0.959	0.2244	Yes
4	Jak2	na	1348	0.944	0.3020	Yes
5	Elk1	na	1723	0.861	0.3673	Yes
6	Mapk3	na	2271	0.767	0.4217	Yes
7	Il6	na	2365	0.753	0.4829	Yes
8	Jak1	na	2997	0.675	0.5281	Yes
9	Csnk2a2	na	4006	0.574	0.5582	Yes
10	Srf	na	4149	0.561	0.6025	Yes
11	Ptpn11	na	4189	0.559	0.6485	Yes
12	Grb2	na	5228	0.478	0.6700	Yes
13	Il6st	na	6080	0.422	0.6901	Yes
14	Jak3	na	6215	0.413	0.7223	Yes
15	Raf1	na	6384	0.403	0.7529	Yes
16	Hras	na	6526	0.393	0.7832	Yes
17	Map2k1	na	7361	0.346	0.7973	Yes
18	Shc1	na	8578	0.282	0.7993	Yes
19	Cebpb	na	8687	0.277	0.8206	Yes
20	Csnk2a1	na	12759	0.103	0.7569	No
21	Il6ra	na	16955	0.011	0.6834	No
22	Sos1	na	52011	-0.192	0.0775	No

Fig 2: BIOCARTA_IL6_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_IL6_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_IL6_PATHWAY