Details for gene set BIOCARTA_MAPK_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_WT.RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Phenotype	RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Upregulated in class	PanKO
GeneSet	BIOCARTA_MAPK_PATHWAY
Enrichment Score (ES)	0.7786694
Normalized Enrichment Score (NES)	1.3525813
Nominal p-value	0.001934236
FDR q-value	0.091811955
FWER p-Value	0.367

Fig 1: Enrichment plot: BIOCARTA_MAPK_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Map3k14	na	318	1.317	0.0248	Yes
2	Tgfb1	na	464	1.234	0.0507	Yes
3	Map3k1	na	499	1.220	0.0782	Yes
4	Pak1	na	661	1.151	0.1020	Yes
5	Tgfb3	na	735	1.123	0.1266	Yes
6	Traf2	na	815	1.098	0.1505	Yes
7	Rela	na	840	1.090	0.1753	Yes
8	Tgfbr1	na	858	1.084	0.2000	Yes
9	Map4k4	na	934	1.061	0.2232	Yes
10	Tgfb2	na	976	1.049	0.2467	Yes
11	Fos	na	1014	1.036	0.2699	Yes
12	Nfkb1	na	1104	1.005	0.2916	Yes
13	Map3k6	na	1261	0.962	0.3110	Yes
14	Jun	na	1278	0.959	0.3329	Yes
15	Rps6ka3	na	1399	0.930	0.3522	Yes
16	Mapk7	na	1615	0.887	0.3689	Yes
17	Elk1	na	1723	0.861	0.3868	Yes
18	Map3k5	na	1892	0.829	0.4030	Yes
19	Rapgef2	na	1908	0.827	0.4218	Yes
20	Mapk6	na	1988	0.814	0.4392	Yes
21	Max	na	1989	0.814	0.4580	Yes
22	Pak2	na	2117	0.791	0.4740	Yes
23	Nfkbia	na	2180	0.779	0.4909	Yes
24	Mapkapk2	na	2219	0.774	0.5081	Yes
25	Mapk3	na	2271	0.767	0.5249	Yes
26	Map4k3	na	2410	0.747	0.5397	Yes
27	Map3k2	na	2597	0.725	0.5531	Yes
28	Map4k5	na	2750	0.705	0.5667	Yes
29	Mapk11	na	2792	0.701	0.5822	Yes
30	Map3k12	na	2874	0.690	0.5967	Yes
31	Daxx	na	3641	0.607	0.5971	Yes
32	Map4k1	na	3891	0.584	0.6062	Yes
33	Atf2	na	3980	0.577	0.6179	Yes
34	Ripk1	na	4046	0.570	0.6299	Yes
35	Map3k8	na	4174	0.560	0.6406	Yes
36	Map2k3	na	4439	0.536	0.6483	Yes
37	Mapk8	na	4468	0.534	0.6601	Yes
38	Rps6ka4	na	4644	0.521	0.6690	Yes
39	Ikbkb	na	4887	0.502	0.6763	Yes
40	Map2k4	na	5148	0.484	0.6829	Yes
41	Map2k7	na	5215	0.479	0.6928	Yes
42	Grb2	na	5228	0.478	0.7036	Yes
43	Mapk13	na	5415	0.466	0.7111	Yes
44	Rps6ka1	na	5418	0.466	0.7218	Yes
45	Rps6ka5	na	5565	0.456	0.7297	Yes
46	Creb1	na	6051	0.424	0.7309	Yes
47	Mknk2	na	6296	0.409	0.7360	Yes
48	Raf1	na	6384	0.403	0.7437	Yes
49	Hras	na	6526	0.393	0.7503	Yes
50	Mapkapk5	na	6587	0.390	0.7582	Yes
51	Map3k11	na	6933	0.370	0.7607	Yes
52	Map2k1	na	7361	0.346	0.7611	Yes
53	Rps6kb1	na	7411	0.344	0.7681	Yes
54	Map3k10	na	7569	0.335	0.7731	Yes
55	Sp1	na	8156	0.304	0.7697	Yes
56	Shc1	na	8578	0.282	0.7687	Yes
57	Map3k3	na	8721	0.275	0.7726	Yes
58	Myc	na	8734	0.274	0.7787	Yes
59	Mknk1	na	9131	0.256	0.7776	No
60	Mapk1	na	9447	0.241	0.7775	No
61	Stat1	na	9895	0.222	0.7747	No
62	Map3k7	na	12299	0.120	0.7348	No
63	Map3k4	na	13420	0.081	0.7168	No
64	Chuk	na	14191	0.059	0.7044	No
65	Tradd	na	14355	0.055	0.7028	No
66	Mapk10	na	47153	-0.001	0.1203	No
67	Mapk9	na	47691	-0.012	0.1111	No
68	Map2k2	na	48899	-0.045	0.0907	No
69	Mapk14	na	48942	-0.047	0.0910	No
70	Mapk12	na	49550	-0.071	0.0818	No
71	Map4k2	na	49703	-0.077	0.0809	No
72	Map2k5	na	52623	-0.226	0.0343	No
73	Rps6ka2	na	53412	-0.283	0.0268	No
74	Rps6kb2	na	53517	-0.289	0.0317	No
75	Map2k6	na	54238	-0.349	0.0269	No
76	Cebpa	na	55213	-0.478	0.0207	No

Fig 2: BIOCARTA_MAPK_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_MAPK_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_MAPK_PATHWAY