Details for gene set REACTOME_CHOLESTEROL_BIOSYNTHESIS[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_WT.RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Phenotype	RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Upregulated in class	WT
GeneSet	REACTOME_CHOLESTEROL_BIOSYNTHESIS
Enrichment Score (ES)	-0.83174753
Normalized Enrichment Score (NES)	-1.3091948
Nominal p-value	0.108208954
FDR q-value	0.5503765
FWER p-Value	0.895

Fig 1: Enrichment plot: REACTOME_CHOLESTEROL_BIOSYNTHESIS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Arv1	na	2364	0.753	0.0033	No
2	Ggps1	na	4085	0.567	0.0069	No
3	Lbr	na	4496	0.532	0.0316	No
4	Plpp6	na	12114	0.126	-0.0960	No
5	Idi2	na	22007	0.000	-0.2715	No
6	Idi2l	na	42016	0.000	-0.6266	No
7	Dhcr24	na	47133	-0.000	-0.7173	No
8	Srebf2	na	47496	-0.008	-0.7233	No
9	Hmgcr	na	50495	-0.112	-0.7697	No
10	Idi1	na	53991	-0.327	-0.8121	Yes
11	Cyp51	na	54295	-0.354	-0.7962	Yes
12	Sqle	na	55143	-0.467	-0.7831	Yes
13	Hmgcs1	na	55302	-0.493	-0.7563	Yes
14	Acat2	na	55487	-0.532	-0.7276	Yes
15	Ebp	na	55541	-0.545	-0.6957	Yes
16	Hsd17b7	na	55755	-0.599	-0.6635	Yes
17	Sc5d	na	55946	-0.672	-0.6265	Yes
18	Pmvk	na	56051	-0.730	-0.5845	Yes
19	Dhcr7	na	56217	-0.871	-0.5351	Yes
20	Tm7sf2	na	56226	-0.890	-0.4817	Yes
21	Msmo1	na	56227	-0.892	-0.4281	Yes
22	Mvk	na	56249	-0.934	-0.3723	Yes
23	Srebf1	na	56265	-0.961	-0.3147	Yes
24	Nsdhl	na	56288	-1.016	-0.2540	Yes
25	Fdft1	na	56289	-1.016	-0.1929	Yes
26	Mvd	na	56292	-1.024	-0.1314	Yes
27	Lss	na	56306	-1.055	-0.0682	Yes
28	Fdps	na	56334	-1.155	0.0008	Yes

Fig 2: REACTOME_CHOLESTEROL_BIOSYNTHESIS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_CHOLESTEROL_BIOSYNTHESIS: Random ES distribution   
Gene set null distribution of ES for REACTOME_CHOLESTEROL_BIOSYNTHESIS