Details for gene set REACTOME_COLLAGEN_DEGRADATION[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_WT.RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Phenotype	RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Upregulated in class	PanKO
GeneSet	REACTOME_COLLAGEN_DEGRADATION
Enrichment Score (ES)	0.8537698
Normalized Enrichment Score (NES)	1.4888995
Nominal p-value	0.0
FDR q-value	0.4582899
FWER p-Value	0.294

Fig 1: Enrichment plot: REACTOME_COLLAGEN_DEGRADATION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Mmp13	na	82	1.559	0.0472	Yes
2	Col6a3	na	130	1.489	0.0929	Yes
3	Col5a2	na	168	1.447	0.1374	Yes
4	Col4a1	na	190	1.423	0.1815	Yes
5	Col12a1	na	209	1.406	0.2250	Yes
6	Col1a1	na	227	1.393	0.2682	Yes
7	Mmp12	na	333	1.307	0.3072	Yes
8	Col1a2	na	383	1.281	0.3463	Yes
9	Mmp14	na	449	1.244	0.3840	Yes
10	Col5a1	na	463	1.234	0.4223	Yes
11	Col6a2	na	473	1.230	0.4605	Yes
12	Col3a1	na	509	1.216	0.4979	Yes
13	Ctsk	na	549	1.199	0.5346	Yes
14	Col4a2	na	569	1.190	0.5714	Yes
15	Col8a1	na	945	1.058	0.5978	Yes
16	Col6a1	na	984	1.047	0.6298	Yes
17	Mmp2	na	1184	0.983	0.6570	Yes
18	Col4a6	na	1338	0.946	0.6838	Yes
19	Mmp15	na	1625	0.884	0.7063	Yes
20	Ctsl	na	2071	0.798	0.7234	Yes
21	Col4a5	na	2106	0.793	0.7475	Yes
22	Col6a6	na	2140	0.788	0.7715	Yes
23	Ctsb	na	2141	0.787	0.7961	Yes
24	Col6a5	na	2520	0.735	0.8123	Yes
25	Col15a1	na	2734	0.707	0.8306	Yes
26	Mmp8	na	3698	0.603	0.8323	Yes
27	Mmp9	na	4200	0.558	0.8408	Yes
28	Ctsd	na	4419	0.538	0.8538	Yes
29	Mmp11	na	9616	0.234	0.7688	No
30	Col13a1	na	14627	0.049	0.6814	No
31	Mmp10	na	14658	0.048	0.6823	No
32	Col11a1	na	18423	0.001	0.6156	No
33	Try10	na	22682	0.000	0.5400	No
34	Mmp20	na	22788	0.000	0.5381	No
35	Prss1	na	23991	0.000	0.5167	No
36	Gm5771	na	26297	0.000	0.4758	No
37	Col26a1	na	28251	0.000	0.4411	No
38	Col19a1	na	29315	0.000	0.4223	No
39	Col10a1	na	29498	0.000	0.4190	No
40	Gm10334	na	31411	0.000	0.3851	No
41	Prss3	na	31872	0.000	0.3769	No
42	Try5	na	33639	0.000	0.3456	No
43	Try4	na	36002	0.000	0.3036	No
44	Col2a1	na	36527	0.000	0.2943	No
45	Mmp1a	na	44424	0.000	0.1541	No
46	Col5a3	na	47407	-0.007	0.1014	No
47	Col8a2	na	48612	-0.036	0.0811	No
48	Prss2	na	48814	-0.042	0.0789	No
49	Phykpl	na	50375	-0.106	0.0545	No
50	Furin	na	50981	-0.138	0.0481	No
51	Col7a1	na	52339	-0.210	0.0305	No
52	Col11a2	na	52637	-0.227	0.0323	No
53	Col18a1	na	53006	-0.254	0.0337	No
54	Tmprss6	na	53753	-0.308	0.0301	No
55	Col25a1	na	55463	-0.528	0.0162	No

Fig 2: REACTOME_COLLAGEN_DEGRADATION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_COLLAGEN_DEGRADATION: Random ES distribution   
Gene set null distribution of ES for REACTOME_COLLAGEN_DEGRADATION