Details for gene set REACTOME_COLLAGEN_FORMATION[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_WT.RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Phenotype	RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Upregulated in class	PanKO
GeneSet	REACTOME_COLLAGEN_FORMATION
Enrichment Score (ES)	0.7767068
Normalized Enrichment Score (NES)	1.4800899
Nominal p-value	0.0019379845
FDR q-value	0.33260667
FWER p-Value	0.349

Fig 1: Enrichment plot: REACTOME_COLLAGEN_FORMATION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Loxl2	na	35	1.675	0.0314	Yes
2	Plod2	na	39	1.654	0.0629	Yes
3	Mmp13	na	82	1.559	0.0919	Yes
4	Adamts2	na	95	1.541	0.1211	Yes
5	Col6a3	na	130	1.489	0.1489	Yes
6	Serpinh1	na	145	1.468	0.1767	Yes
7	Ctss	na	163	1.451	0.2041	Yes
8	Col5a2	na	168	1.447	0.2317	Yes
9	Col4a1	na	190	1.423	0.2585	Yes
10	Loxl1	na	200	1.410	0.2853	Yes
11	Col12a1	na	209	1.406	0.3120	Yes
12	Col1a1	na	227	1.393	0.3383	Yes
13	P3h2	na	234	1.385	0.3646	Yes
14	Col1a2	na	383	1.281	0.3864	Yes
15	Lox	na	457	1.239	0.4088	Yes
16	Col5a1	na	463	1.234	0.4323	Yes
17	Col6a2	na	473	1.230	0.4556	Yes
18	Col3a1	na	509	1.216	0.4782	Yes
19	Col4a2	na	569	1.190	0.4999	Yes
20	Col28a1	na	599	1.179	0.5218	Yes
21	Crtap	na	636	1.165	0.5435	Yes
22	P3h3	na	673	1.146	0.5647	Yes
23	Col16a1	na	843	1.090	0.5825	Yes
24	Col8a1	na	945	1.058	0.6009	Yes
25	Col6a1	na	984	1.047	0.6202	Yes
26	Col4a6	na	1338	0.946	0.6320	Yes
27	Pcolce	na	1427	0.925	0.6481	Yes
28	Col14a1	na	1490	0.913	0.6645	Yes
29	Ctsl	na	2071	0.798	0.6694	Yes
30	Col4a5	na	2106	0.793	0.6839	Yes
31	Col6a6	na	2140	0.788	0.6984	Yes
32	Ctsb	na	2141	0.787	0.7134	Yes
33	Col6a5	na	2520	0.735	0.7207	Yes
34	Col15a1	na	2734	0.707	0.7305	Yes
35	Adamts14	na	2864	0.691	0.7414	Yes
36	Loxl4	na	3488	0.621	0.7422	Yes
37	Loxl3	na	3544	0.615	0.7529	Yes
38	P3h1	na	3889	0.584	0.7580	Yes
39	Colgalt1	na	4134	0.562	0.7644	Yes
40	Mmp9	na	4200	0.558	0.7739	Yes
41	Plod3	na	4605	0.524	0.7767	Yes
42	P4ha3	na	6787	0.379	0.7452	No
43	Pxdn	na	8584	0.282	0.7187	No
44	P4ha1	na	8773	0.273	0.7205	No
45	Pcolce2	na	11047	0.171	0.6834	No
46	Adamts3	na	11887	0.134	0.6711	No
47	Col4a4	na	12382	0.116	0.6645	No
48	Col23a1	na	12479	0.113	0.6650	No
49	Tll1	na	12906	0.098	0.6593	No
50	Ppib	na	13062	0.093	0.6583	No
51	P4hb	na	13812	0.070	0.6464	No
52	Col9a2	na	14293	0.056	0.6389	No
53	Col13a1	na	14627	0.049	0.6339	No
54	P4ha2	na	15220	0.036	0.6241	No
55	Col11a1	na	18423	0.001	0.5672	No
56	Mmp20	na	22788	0.000	0.4897	No
57	Col26a1	na	28251	0.000	0.3927	No
58	Col19a1	na	29315	0.000	0.3738	No
59	Col10a1	na	29498	0.000	0.3706	No
60	Col2a1	na	36527	0.000	0.2458	No
61	Col9a1	na	47356	-0.006	0.0536	No
62	Col5a3	na	47407	-0.007	0.0528	No
63	Col8a2	na	48612	-0.036	0.0321	No
64	Col17a1	na	48666	-0.037	0.0319	No
65	Col9a3	na	49707	-0.077	0.0149	No
66	Tll2	na	50217	-0.099	0.0077	No
67	Plod1	na	52210	-0.201	-0.0238	No
68	Col7a1	na	52339	-0.210	-0.0221	No
69	Col11a2	na	52637	-0.227	-0.0230	No
70	Col24a1	na	52901	-0.245	-0.0230	No
71	Col18a1	na	53006	-0.254	-0.0200	No
72	Col27a1	na	54059	-0.333	-0.0323	No
73	Col25a1	na	55463	-0.528	-0.0472	No
74	Bmp1	na	55629	-0.567	-0.0393	No
75	Col22a1	na	55648	-0.572	-0.0287	No
76	Col20a1	na	56054	-0.732	-0.0219	No
77	Colgalt2	na	56363	-1.446	0.0002	No

Fig 2: REACTOME_COLLAGEN_FORMATION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_COLLAGEN_FORMATION: Random ES distribution   
Gene set null distribution of ES for REACTOME_COLLAGEN_FORMATION