Details for gene set WP_INSULIN

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_WT.RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Phenotype	RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Upregulated in class	PanKO
GeneSet	WP_INSULIN_SIGNALING
Enrichment Score (ES)	0.73448557
Normalized Enrichment Score (NES)	1.3788503
Nominal p-value	0.010121457
FDR q-value	0.18691397
FWER p-Value	0.476

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Shc2	na	76	1.571	0.0186	Yes
2	Prkcd	na	198	1.410	0.0343	Yes
3	Arf6	na	294	1.338	0.0496	Yes
4	Map3k14	na	318	1.317	0.0659	Yes
5	Flot1	na	336	1.306	0.0822	Yes
6	Map3k1	na	499	1.220	0.0948	Yes
7	Ehd2	na	652	1.157	0.1067	Yes
8	Pik3cd	na	850	1.088	0.1170	Yes
9	Rac2	na	928	1.064	0.1292	Yes
10	Map4k4	na	934	1.061	0.1425	Yes
11	Rhoj	na	964	1.051	0.1554	Yes
12	Myo1c	na	965	1.051	0.1687	Yes
13	Fos	na	1014	1.036	0.1810	Yes
14	Grb10	na	1034	1.030	0.1937	Yes
15	Map3k6	na	1261	0.962	0.2019	Yes
16	Jun	na	1278	0.959	0.2138	Yes
17	Cbl	na	1334	0.947	0.2248	Yes
18	Stxbp3	na	1398	0.930	0.2355	Yes
19	Rps6ka3	na	1399	0.930	0.2473	Yes
20	Kif5b	na	1424	0.925	0.2586	Yes
21	Sh2b2	na	1447	0.921	0.2699	Yes
22	Rhoq	na	1604	0.888	0.2784	Yes
23	Mapk7	na	1615	0.887	0.2894	Yes
24	Elk1	na	1723	0.861	0.2985	Yes
25	Prkch	na	1884	0.831	0.3062	Yes
26	Map3k5	na	1892	0.829	0.3166	Yes
27	Kif3a	na	1924	0.824	0.3265	Yes
28	Mapk6	na	1988	0.814	0.3357	Yes
29	Stxbp1	na	2154	0.785	0.3427	Yes
30	Sos2	na	2210	0.775	0.3515	Yes
31	Pik3cg	na	2217	0.774	0.3613	Yes
32	Mapk3	na	2271	0.767	0.3700	Yes
33	Sgk1	na	2282	0.764	0.3796	Yes
34	Socs1	na	2328	0.758	0.3884	Yes
35	Akt1	na	2391	0.749	0.3968	Yes
36	Map4k3	na	2410	0.747	0.4059	Yes
37	Eif4ebp1	na	2481	0.740	0.4141	Yes
38	Eif4e	na	2524	0.735	0.4226	Yes
39	Map3k9	na	2555	0.731	0.4314	Yes
40	Map3k2	na	2597	0.725	0.4398	Yes
41	Rps6ka6	na	2616	0.723	0.4487	Yes
42	Egr1	na	2653	0.719	0.4572	Yes
43	Map4k5	na	2750	0.705	0.4644	Yes
44	Cap1	na	2765	0.704	0.4731	Yes
45	Mapk11	na	2792	0.701	0.4815	Yes
46	Map3k12	na	2874	0.690	0.4889	Yes
47	Prkaa1	na	2970	0.678	0.4958	Yes
48	Cyth3	na	3133	0.661	0.5013	Yes
49	Cblb	na	3153	0.658	0.5093	Yes
50	Rrad	na	3169	0.656	0.5173	Yes
51	Socs3	na	3198	0.653	0.5251	Yes
52	Ptpn1	na	3208	0.651	0.5332	Yes
53	Inppl1	na	3279	0.644	0.5402	Yes
54	Map3k13	na	3328	0.639	0.5474	Yes
55	Cblc	na	3469	0.624	0.5528	Yes
56	Pik3c2a	na	3504	0.620	0.5601	Yes
57	Snap23	na	3752	0.599	0.5633	Yes
58	Map4k1	na	3891	0.584	0.5682	Yes
59	Prkcb	na	3998	0.575	0.5737	Yes
60	Prkci	na	4121	0.563	0.5786	Yes
61	Srf	na	4149	0.561	0.5853	Yes
62	Map3k8	na	4174	0.560	0.5919	Yes
63	Ptpn11	na	4189	0.559	0.5988	Yes
64	Map2k3	na	4439	0.536	0.6011	Yes
65	Mapk8	na	4468	0.534	0.6074	Yes
66	Rps6ka4	na	4644	0.521	0.6109	Yes
67	Sgk3	na	4841	0.506	0.6139	Yes
68	Pik3cb	na	4875	0.503	0.6197	Yes
69	Ikbkb	na	4887	0.502	0.6258	Yes
70	Rac1	na	5031	0.492	0.6295	Yes
71	Map2k4	na	5148	0.484	0.6336	Yes
72	Map2k7	na	5215	0.479	0.6385	Yes
73	Grb2	na	5228	0.478	0.6443	Yes
74	Crk	na	5325	0.472	0.6486	Yes
75	Mapk13	na	5415	0.466	0.6530	Yes
76	Rps6ka1	na	5418	0.466	0.6588	Yes
77	Rps6ka5	na	5565	0.456	0.6620	Yes
78	Rheb	na	5642	0.451	0.6664	Yes
79	Slc2a1	na	5720	0.446	0.6707	Yes
80	Igf1r	na	5859	0.436	0.6737	Yes
81	Pdpk1	na	6006	0.428	0.6766	Yes
82	Gab1	na	6136	0.418	0.6796	Yes
83	Inpp4a	na	6217	0.413	0.6834	Yes
84	Arf1	na	6227	0.412	0.6885	Yes
85	Gyg	na	6319	0.406	0.6920	Yes
86	Raf1	na	6384	0.403	0.6960	Yes
87	Prkca	na	6428	0.400	0.7003	Yes
88	Hras	na	6526	0.393	0.7035	Yes
89	Map3k11	na	6933	0.370	0.7010	Yes
90	Pik3ca	na	6982	0.367	0.7048	Yes
91	Flot2	na	7167	0.356	0.7061	Yes
92	Map2k1	na	7361	0.346	0.7070	Yes
93	Rps6kb1	na	7411	0.344	0.7105	Yes
94	Vamp2	na	7421	0.343	0.7147	Yes
95	Grb14	na	7435	0.342	0.7188	Yes
96	Xbp1	na	7484	0.340	0.7223	Yes
97	Map3k10	na	7569	0.335	0.7250	Yes
98	Gsk3b	na	7589	0.334	0.7289	Yes
99	Pik3c3	na	7965	0.313	0.7262	Yes
100	Ehd1	na	8313	0.295	0.7238	Yes
101	Pik3r3	na	8461	0.287	0.7248	Yes
102	Irs1	na	8540	0.284	0.7270	Yes
103	Shc1	na	8578	0.282	0.7300	Yes
104	Pik3r2	na	8653	0.279	0.7322	Yes
105	Map3k3	na	8721	0.275	0.7345	Yes
106	Ptprf	na	9198	0.253	0.7292	No
107	Mapk1	na	9447	0.241	0.7279	No
108	Akt2	na	9459	0.241	0.7307	No
109	Mtor	na	9651	0.233	0.7303	No
110	Stxbp2	na	9738	0.228	0.7317	No
111	Pten	na	10384	0.200	0.7227	No
112	Trib3	na	10509	0.194	0.7230	No
113	Ppp1cc	na	11066	0.170	0.7153	No
114	Tbc1d4	na	11264	0.161	0.7138	No
115	Ppp1ccb	na	11684	0.143	0.7082	No
116	Map3k7	na	12299	0.120	0.6987	No
117	Pfkl	na	12456	0.114	0.6974	No
118	Irs3	na	12556	0.110	0.6971	No
119	Mink1	na	12803	0.101	0.6940	No
120	Map3k4	na	13420	0.081	0.6840	No
121	Tsc2	na	14224	0.058	0.6705	No
122	Arhgap33	na	14919	0.042	0.6587	No
123	Prkaa2	na	15232	0.036	0.6536	No
124	Tsc1	na	16525	0.016	0.6308	No
125	Shc3	na	18229	0.002	0.6005	No
126	Rapgef1	na	18279	0.002	0.5997	No
127	Snap25	na	20535	0.000	0.5596	No
128	Irs4	na	31394	0.000	0.3664	No
129	Mapk10	na	47153	-0.001	0.0862	No
130	Mapk9	na	47691	-0.012	0.0768	No
131	Stx4a	na	48263	-0.026	0.0669	No
132	Slc2a4	na	48569	-0.034	0.0619	No
133	Stxbp4	na	48684	-0.038	0.0604	No
134	Map2k2	na	48899	-0.045	0.0572	No
135	Mapk14	na	48942	-0.047	0.0570	No
136	Pik3c2g	na	49061	-0.051	0.0556	No
137	Foxo3	na	49150	-0.054	0.0547	No
138	Insr	na	49459	-0.067	0.0501	No
139	Mapk12	na	49550	-0.071	0.0493	No
140	Map4k2	na	49703	-0.077	0.0476	No
141	Rab4a	na	50016	-0.089	0.0432	No
142	Pfkm	na	50430	-0.110	0.0372	No
143	Enpp1	na	50554	-0.116	0.0365	No
144	Sorbs1	na	50751	-0.126	0.0346	No
145	Gys1	na	50840	-0.131	0.0347	No
146	Pik3r4	na	51341	-0.157	0.0278	No
147	Gys2	na	51435	-0.162	0.0282	No
148	Foxo1	na	51879	-0.185	0.0227	No
149	Sos1	na	52011	-0.192	0.0228	No
150	Map2k5	na	52623	-0.226	0.0148	No
151	Pik3r1	na	52729	-0.233	0.0159	No
152	Sgk2	na	53061	-0.257	0.0133	No
153	Prkcq	na	53164	-0.263	0.0148	No
154	Rps6ka2	na	53412	-0.283	0.0140	No
155	Rps6kb2	na	53517	-0.289	0.0158	No
156	Map2k6	na	54238	-0.349	0.0074	No
157	Mapk4	na	55958	-0.677	-0.0145	No
158	Prkcz	na	56150	-0.803	-0.0078	No
159	Lipe	na	56244	-0.928	0.0024	No