Details for gene set WP_TRYPTOPHAN_METABOLISM[GSEA]

Table: GSEA Results Summary

Dataset	RPKM_matrix___PanKO_vs_WT.RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Phenotype	RPKM_matrix___PanKO_vs_WT.cls#PanKO_versus_WT
Upregulated in class	WT
GeneSet	WP_TRYPTOPHAN_METABOLISM
Enrichment Score (ES)	-0.5939576
Normalized Enrichment Score (NES)	-1.2297497
Nominal p-value	0.18069816
FDR q-value	0.48477343
FWER p-Value	0.872

Fig 1: Enrichment plot: WP_TRYPTOPHAN_METABOLISM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Aldh1a2	na	595	1.180	0.0613	No
2	Prmt1	na	2108	0.792	0.0827	No
3	Cyp1b1	na	2319	0.759	0.1253	No
4	Mdm2	na	3696	0.603	0.1376	No
5	Rnf25	na	5110	0.487	0.1421	No
6	Acmsd	na	6827	0.377	0.1346	No
7	Ubr5	na	7795	0.323	0.1371	No
8	Ube3a	na	10425	0.198	0.1025	No
9	Asmt	na	13057	0.093	0.0615	No
10	Cyp2j6	na	13226	0.088	0.0638	No
11	Cyp2f2	na	13637	0.075	0.0611	No
12	Wars1	na	13899	0.067	0.0606	No
13	Aoc1	na	14477	0.052	0.0535	No
14	Ogdh	na	14966	0.041	0.0473	No
15	Cyp7b1	na	16298	0.019	0.0249	No
16	Cyp1a2	na	16838	0.012	0.0160	No
17	Tph1	na	21433	0.000	-0.0655	No
18	Cyp19a1	na	35417	0.000	-0.3137	No
19	Aanat	na	36869	0.000	-0.3395	No
20	Dhcr24	na	47133	-0.000	-0.5216	No
21	Kynu	na	48250	-0.026	-0.5399	No
22	Aox1	na	50110	-0.094	-0.5672	No
23	Aadat	na	50112	-0.094	-0.5614	No
24	Echs1	na	51837	-0.183	-0.5809	Yes
25	Maob	na	52445	-0.216	-0.5785	Yes
26	Tdo2	na	53316	-0.275	-0.5772	Yes
27	Aldh2	na	53418	-0.283	-0.5617	Yes
28	Cyp1a1	na	53590	-0.295	-0.5468	Yes
29	Ido1	na	53714	-0.304	-0.5305	Yes
30	Cyp4f14	na	54369	-0.362	-0.5201	Yes
31	Aldh1a1	na	54372	-0.362	-0.4980	Yes
32	Hadh	na	54754	-0.407	-0.4800	Yes
33	Ddc	na	54837	-0.417	-0.4560	Yes
34	Aldh3a2	na	55518	-0.539	-0.4353	Yes
35	Cat	na	55624	-0.567	-0.4026	Yes
36	Hsd17b10	na	55641	-0.571	-0.3681	Yes
37	Inmt	na	55653	-0.573	-0.3334	Yes
38	Aldh9a1	na	55808	-0.619	-0.2985	Yes
39	Gcdh	na	55914	-0.660	-0.2601	Yes
40	Acat1	na	55969	-0.682	-0.2196	Yes
41	Afmid	na	56056	-0.735	-0.1763	Yes
42	Haao	na	56089	-0.768	-0.1301	Yes
43	Cyp2e1	na	56174	-0.819	-0.0817	Yes
44	Cyp2c55	na	56362	-1.400	0.0003	Yes

Fig 2: WP_TRYPTOPHAN_METABOLISM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: WP_TRYPTOPHAN_METABOLISM: Random ES distribution   
Gene set null distribution of ES for WP_TRYPTOPHAN_METABOLISM