Details for gene set BIOCARTA_EIF4_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	KO_vs_WTandHET.KO_vs_WTandHET.cls#WT_versus_KO
Phenotype	KO_vs_WTandHET.cls#WT_versus_KO
Upregulated in class	WT
GeneSet	BIOCARTA_EIF4_PATHWAY
Enrichment Score (ES)	0.4671245
Normalized Enrichment Score (NES)	1.4715501
Nominal p-value	0.11821705
FDR q-value	0.647898
FWER p-Value	0.729

Fig 1: Enrichment plot: BIOCARTA_EIF4_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Irs1	Irs1	1207	0.829	0.0847	Yes
2	Akt1	Akt1	1613	0.701	0.1824	Yes
3	Pik3r1	Pik3r1	1878	0.634	0.2752	Yes
4	Mapk14	Mapk14	3143	0.436	0.2932	Yes
5	Pdk2	Pdk2	4301	0.334	0.2989	Yes
6	Mtor	Mtor	4779	0.298	0.3275	Yes
7	Ghr	Ghr	4898	0.289	0.3698	Yes
8	Pik3ca	Pik3ca	5000	0.282	0.4117	Yes
9	Eif4a2	Eif4a2	5460	0.252	0.4335	Yes
10	Mapk3	Mapk3	5607	0.243	0.4671	Yes
11	Pdpk1	Pdpk1	6478	0.199	0.4629	No
12	Mknk1	Mknk1	7745	0.139	0.4321	No
13	Rps6kb1	Rps6kb1	7783	0.137	0.4530	No
14	Mapk1	Mapk1	8711	0.099	0.4300	No
15	Prkcb	Prkcb	8829	0.094	0.4406	No
16	Pten	Pten	12340	-0.032	0.2973	No
17	Eif4e	Eif4e	12391	-0.034	0.3007	No
18	Eif4ebp1	Eif4ebp1	13215	-0.064	0.2764	No
19	Prkca	Prkca	16483	-0.197	0.1704	No
20	Pabpc1	Pabpc1	18643	-0.301	0.1284	No
21	Eif4a1	Eif4a1	21133	-0.509	0.1065	No

Fig 2: BIOCARTA_EIF4_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: BIOCARTA_EIF4_PATHWAY: Random ES distribution   
Gene set null distribution of ES for BIOCARTA_EIF4_PATHWAY